Evidenzbasierte Empfehlungen zur Primärbehandlung von Mammakarzinomen

Die Organkommission 1Mammaa der Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) hat sich die Erarbeitung von Empfehlungen zur Therapie von Mammakarzinomen zur Aufgabe gemacht. Zielsetzung war die Definition des aktuellen evidenzbasierten Wissensstandes zur Primärtherapie dieser Erkrankung. Zu aktuellen Aspekten wurden Kernaussagen formuliert und nach zweierlei Gesichtspunkten bewertet: ± Festlegung des Evidenzniveaus (Level of Evidence, LOE) nach Sichtung der aktuellen Literatur und Bewertung der verfügbaren Datenqualität. ± Festlegung des Empfehlungsgrades entsprechend der Konsistenz der Ergebnisse verschiedener Untersuchungen und des klinischen Stellenwertes.

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