Markedly unbiased codon usage in Bacillus subtilis.

Codon usage for 21 Bacillus subtilis chromosomal genes was analyzed and found to be unusual compared with that of Escherichia coli or Saccharomyces cerevisiae. All codons are used more or less equally. The unusual codon usage in B. subtilis may be related to the unique organization of its tRNA genes.

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