Fractional Anisotropic Diffusion for Noise Reduction in Magnetic Resonance Images

We extend the method of anisotropic diffusion for noise reduction in digital images to the case when the diffusion processes are non-Gaussian and Lévy distributed. This yields a fractional diffusion equation characterised by the Lévy index. A solution to this equation is considered and a numerical algorithm developed. The algorithm is then applied as a case study to the problem of reducing noise in magnetic resonance imaging. The focus of this study is on diffusion weighted images which have low signal-to-noise ratios.

[1]  N M Hylton,et al.  Signal to Noise in Derived NMR Images , 1984, Magnetic resonance in medicine.

[2]  J N Lee,et al.  Automated MR image synthesis: feasibility studies. , 1984, Radiology.

[3]  Denis Le Bihan,et al.  Imagerie de diffusion in-vivo par résonance magnétique nucléaire , 1985 .

[4]  D. Le Bihan,et al.  Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. , 1988, Radiology.

[5]  T F Nonnenmacher,et al.  Fractional integral and differential equations for a class of Levy-type probability densities , 1990 .

[6]  Mario Bertero,et al.  Introduction to Inverse Problems in Imaging , 1998 .

[7]  James S. Duncan,et al.  Medical Image Analysis , 1999, IEEE Pulse.

[8]  L. Schwartz,et al.  Bone marrow segmentation in leukemia using diffusion and T 2 weighted echo planar magnetic resonance imaging , 2000, NMR in biomedicine.

[9]  A. Padhani Dynamic contrast‐enhanced MRI in clinical oncology: Current status and future directions , 2002, Journal of magnetic resonance imaging : JMRI.

[10]  V. Wedeen,et al.  Reduction of eddy‐current‐induced distortion in diffusion MRI using a twice‐refocused spin echo , 2003, Magnetic resonance in medicine.

[11]  J. Hyde,et al.  Characterization of continuously distributed cortical water diffusion rates with a stretched‐exponential model , 2003, Magnetic resonance in medicine.

[12]  T. Takahara,et al.  Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display. , 2004, Radiation medicine.

[13]  Albert Einstein,et al.  On the Motion of Small Particles Suspended in Liquids at Rest Required by the Molecular-Kinetic Theory of Heat ∗ , 2004 .

[14]  Stefan Thurner,et al.  Anomalous diffusion in view of Einstein's 1905 theory of Brownian motion , 2005 .

[15]  P. Kingsley,et al.  Introduction to diffusion tensor imaging mathematics: Part III. Tensor calculation, noise, simulations, and optimization , 2006 .

[16]  Dow-Mu Koh,et al.  Practical aspects of assessing tumors using clinical diffusion-weighted imaging in the body. , 2007, Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine.

[17]  D. Collins,et al.  Diffusion-weighted MRI in the body: applications and challenges in oncology. , 2007, AJR. American journal of roentgenology.

[18]  J. Blackledge Application of the Fractional Diffusion Equation for Predicting Market Behaviour , 2010 .