Fine polystyrene microplastics render immune responses more vulnerable to two veterinary antibiotics in a bivalve species.

[1]  Wei Shi,et al.  Modulatory function of calmodulin on phagocytosis and potential regulation mechanisms in the blood clam Tegillarca granosa. , 2020, Developmental and comparative immunology.

[2]  Wei Shi,et al.  Ocean acidification impedes gustation-mediated feeding behavior by disrupting gustatory signal transduction in the black sea bream, Acanthopagrus schlegelii. , 2020, Marine environmental research.

[3]  Wei Shi,et al.  Immunotoxicity and neurotoxicity of bisphenol A and microplastics alone or in combination to a bivalve species, Tegillarca granosa. , 2020, Environmental pollution.

[4]  Yu Tang,et al.  Microplastics aggravate the bioaccumulation of two waterborne veterinary antibiotics in an edible bivalve species: potential mechanisms and implications for human health. , 2020, Environmental science & technology.

[5]  Wei Shi,et al.  Nanoparticles decrease the byssal attachment strength of the thick shell mussel Mytilus coruscus. , 2020, Chemosphere.

[6]  Yu Tang,et al.  Immunotoxicity of petroleum hydrocarbons and microplastics alone or in combination to a bivalve species: Synergic impacts and potential toxication mechanisms. , 2020, The Science of the total environment.

[7]  Wei Shi,et al.  Acetylcholine suppresses phagocytosis via binding to muscarinic- and nicotinic-acetylcholine receptors and subsequently interfering Ca2+- and NFκB-signaling pathways in blood clam. , 2020, Fish & shellfish immunology.

[8]  Wei Shi,et al.  Immunotoxicities of microplastics and sertraline, alone and in combination, to a bivalve species: size-dependent interaction and potential toxication mechanism. , 2020, Journal of hazardous materials.

[9]  Jia Du,et al.  A review of microplastics in the aquatic environmental: distribution, transport, ecotoxicology, and toxicological mechanisms , 2020, Environmental Science and Pollution Research.

[10]  Wei Shi,et al.  Immunotoxicity of microplastics and two persistent organic pollutants alone or in combination to a bivalve species. , 2019, Environmental pollution.

[11]  M. Guida,et al.  Microplastic-induced damage in early embryonal development of sea urchin Sphaerechinus granularis. , 2019, Environmental research.

[12]  M. Hoogenboom,et al.  Impacts of microplastics on growth and health of hermatypic corals are species-specific. , 2019, Environmental pollution.

[13]  Cristiano Bertolucci,et al.  Microplastics induce transcriptional changes, immune response and behavioral alterations in adult zebrafish , 2019, Scientific Reports.

[14]  Wei Shi,et al.  Exposure to waterborne nTiO2 reduces fertilization success and increases polyspermy in a bivalve mollusc: A threat to population recruitment. , 2019, Environmental science & technology.

[15]  Wei Shi,et al.  Fluoxetine suppresses the immune responses of blood clams by reducing haemocyte viability, disturbing signal transduction and imposing physiological stress. , 2019, The Science of the total environment.

[16]  Yu Han,et al.  Immunotoxicity of four nanoparticles to a marine bivalve species, Tegillarca granosa. , 2019, Journal of hazardous materials.

[17]  M. Yan,et al.  Exogenous Ca2+ mitigates the toxic effects of TiO2 nanoparticles on phagocytosis, cell viability, and apoptosis in haemocytes of a marine bivalve mollusk, Tegillarca granosa. , 2019, Environmental pollution.

[18]  J. Prunier,et al.  Ecotoxicity of polyethylene nanoplastics from the North Atlantic oceanic gyre on freshwater and marine organisms (microalgae and filter-feeding bivalves) , 2019, Environmental Science and Pollution Research.

[19]  A. Alfaro,et al.  In vitro study of apoptosis in mussel (Perna canaliculus) haemocytes induced by lipopolysaccharide , 2019, Aquaculture.

[20]  Wei Shi,et al.  Exposure to 2,3,7,8‐tetrachlorodibenzo‐paradioxin (TCDD) hampers the host defense capability of a bivalve species, Tegillarca granosa , 2019, Fish & shellfish immunology.

[21]  M. Ibáñez,et al.  Occurrence of antibiotics and bacterial resistance in wastewater and sea water from the Antarctic. , 2019, Journal of hazardous materials.

[22]  J. Seo,et al.  Adverse effects of two pharmaceuticals acetaminophen and oxytetracycline on life cycle parameters, oxidative stress, and defensome system in the marine rotifer Brachionus rotundiformis. , 2018, Aquatic toxicology.

[23]  L. Guilhermino,et al.  Microplastics increase mercury bioconcentration in gills and bioaccumulation in the liver, and cause oxidative stress and damage in Dicentrarchus labrax juveniles , 2018, Scientific Reports.

[24]  K. Qu,et al.  Polystyrene microplastics alter the behavior, energy reserve and nutritional composition of marine jacopever (Sebastes schlegelii). , 2018, Journal of hazardous materials.

[25]  Wei Shi,et al.  Waterborne Cd2+ weakens the immune responses of blood clam through impacting Ca2+ signaling and Ca2+ related apoptosis pathways , 2018, Fish & shellfish immunology.

[26]  M. Yan,et al.  Ocean Acidification Affects the Cytoskeleton, Lysozymes, and Nitric Oxide of Hemocytes: A Possible Explanation for the Hampered Phagocytosis in Blood Clams, Tegillarca granosa , 2018, Front. Physiol..

[27]  S. Limbu,et al.  Environmental concentrations of antibiotics impair zebrafish gut health. , 2018, Environmental pollution.

[28]  H. Goossens,et al.  Global increase and geographic convergence in antibiotic consumption between 2000 and 2015 , 2018, Proceedings of the National Academy of Sciences.

[29]  Jinrong Peng,et al.  p73 coordinates with Δ133p53 to promote DNA double-strand break repair , 2018, Cell Death & Differentiation.

[30]  T. Nakano,et al.  Effect of excessive doses of oxytetracycline on stress-related biomarker expression in coho salmon , 2018, Environmental Science and Pollution Research.

[31]  M. A. Pavanato,et al.  Protective effect of quercetin against oxidative stress induced by oxytetracycline in muscle of silver catfish , 2018 .

[32]  Juan Du,et al.  Antibiotics in the coastal water of the South Yellow Sea in China: Occurrence, distribution and ecological risks. , 2017, The Science of the total environment.

[33]  M. Gupta,et al.  Insight into cytotoxicity of Mg nanocomposites using MTT assay technique. , 2017, Materials science & engineering. C, Materials for biological applications.

[34]  M. Yan,et al.  Ca2+-channel and calmodulin play crucial roles in the fast electrical polyspermy blocking of Tegillarca granosa (Bivalvia: Arcidae) , 2017 .

[35]  Wei Shi,et al.  Immunotoxicity of nanoparticle nTiO2 to a commercial marine bivalve species, Tegillarca granosa , 2017, Fish & shellfish immunology.

[36]  R. Geyer,et al.  Production, use, and fate of all plastics ever made , 2017, Science Advances.

[37]  T. Fan,et al.  Molecular characteristics of hemoglobins in blood clam and their immune responses to bacterial infection. , 2017, International journal of biological macromolecules.

[38]  Wei Shi,et al.  Benzo[a]pyrene exposure under future ocean acidification scenarios weakens the immune responses of blood clam, Tegillarca granosa , 2017, Fish & shellfish immunology.

[39]  Jiong-ming Zhang,et al.  Population Genetic Structure of the Blood Clam, Tegillarca granosa, Along the Pacific Coast of Asia: Isolation by Distance in the Sea , 2016, Malacologia.

[40]  Wei Li,et al.  Identification of a regulation network in response to cadmium toxicity using blood clam Tegillarca granosa as model , 2016, Scientific Reports.

[41]  Patchari Yocawibun,et al.  The cellular death pattern of primary haemocytes isolated from the black tiger shrimp (Penaeus monodon). , 2016, Fish & shellfish immunology.

[42]  I. Caçador,et al.  Microplastics as vector for heavy metal contamination from the marine environment , 2016 .

[43]  Haibo Zhang,et al.  Levels, distributions and sources of veterinary antibiotics in the sediments of the Bohai Sea in China and surrounding estuaries. , 2016, Marine pollution bulletin.

[44]  Wei Shi,et al.  Ocean acidification weakens the immune response of blood clam through hampering the NF-kappa β and toll-like receptor pathways. , 2016, Fish & shellfish immunology.

[45]  R. Leinfelder,et al.  The geological cycle of plastics and their use as a stratigraphic indicator of the Anthropocene , 2016 .

[46]  M. Adhya,et al.  Gal/GalNAc specific multiple lectins in marine bivalve Anadara granosa. , 2016, Fish & shellfish immunology.

[47]  Johan Robbens,et al.  Oyster reproduction is affected by exposure to polystyrene microplastics , 2016, Proceedings of the National Academy of Sciences.

[48]  Nikolai Maximenko,et al.  A global inventory of small floating plastic debris , 2015 .

[49]  A. Marcomini,et al.  Titanium dioxide nanoparticles stimulate sea urchin immune cell phagocytic activity involving TLR/p38 MAPK-mediated signalling pathway , 2015, Scientific Reports.

[50]  V. L. Tornisielo,et al.  Genotoxic responses of juvenile tilapia (Oreochromis niloticus) exposed to florfenicol and oxytetracycline. , 2015, Chemosphere.

[51]  J. Balzarini,et al.  Exposure of Trypanosoma brucei to an N-acetylglucosamine-Binding Lectin Induces VSG Switching and Glycosylation Defects Resulting in Reduced Infectivity , 2015, PLoS neglected tropical diseases.

[52]  C. Wilcox,et al.  Plastic waste inputs from land into the ocean , 2015, Science.

[53]  L. Pan,et al.  Effect of florfenicol on selected parameters of immune and antioxidant systems, and damage indexes of juvenile Litopenaeus vannamei following oral administration , 2014 .

[54]  K. L. Law,et al.  Microplastics in the seas , 2014, Science.

[55]  Wen Wang,et al.  Function of two novel single-CRD containing C-type lectins in innate immunity from Eriocheir sinensis. , 2014, Fish & shellfish immunology.

[56]  S. Teh,et al.  Long-Term Sorption of Metals Is Similar among Plastic Types: Implications for Plastic Debris in Aquatic Environments , 2014, PloS one.

[57]  Xiao-Fan Zhao,et al.  C-type Lectin Binds to β-Integrin to Promote Hemocytic Phagocytosis in an Invertebrate* , 2013, The Journal of Biological Chemistry.

[58]  C. Miranda,et al.  Effect of florfenicol and oxytetracycline treatments on the intensive larval culture of the Chilean scallop Argopecten purpuratus (Lamarck, 1819) , 2013 .

[59]  R. Sharafati-chaleshtori,et al.  Residues of oxytetracycline in cultured rainbow trout. , 2013, Pakistan journal of biological sciences : PJBS.

[60]  Richard C. Thompson,et al.  The physical impacts of microplastics on marine organisms: a review. , 2013, Environmental pollution.

[61]  Thomas Backhaus,et al.  Human Health Risk Assessment (HHRA) for Environmental Development and Transfer of Antibiotic Resistance , 2013, Environmental health perspectives.

[62]  Y. Bao,et al.  Hemoglobin and its derived peptides from blood clam (Tegillarca granosa) exhibiting an antimicrobial activity , 2013 .

[63]  H. Olff,et al.  Cross-habitat interactions among bivalve species control community structure on intertidal flats. , 2013, Ecology.

[64]  G. Pojana,et al.  Immunomodulation by Different Types of N-Oxides in the Hemocytes of the Marine Bivalve Mytilus galloprovincialis , 2012, PloS one.

[65]  F. Guardiola,et al.  Modulation of the immune parameters and expression of genes of gilthead seabream (Sparus aurata L.) by dietary administration of oxytetracycline , 2012 .

[66]  Yaqi Cai,et al.  Investigation of antibiotics in mollusks from coastal waters in the Bohai Sea of China. , 2012, Environmental pollution.

[67]  Gan Zhang,et al.  Occurrence and distribution of antibiotics in coastal water of the Bohai Bay, China: impacts of river discharge and aquaculture activities. , 2011, Environmental pollution.

[68]  K. Jeyasubramanian,et al.  Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation. , 2011, Nanomedicine : nanotechnology, biology, and medicine.

[69]  Huan Zhang,et al.  C-Type Lectin in Chlamys farreri (CfLec-1) Mediating Immune Recognition and Opsonization , 2011, PloS one.

[70]  Klaus Kümmerer,et al.  The presence of pharmaceuticals in the environment due to human use--present knowledge and future challenges. , 2009, Journal of environmental management.

[71]  Richard C. Thompson,et al.  Ingested microscopic plastic translocates to the circulatory system of the mussel, Mytilus edulis (L). , 2008, Environmental science & technology.

[72]  G. Vasta,et al.  A Galectin of Unique Domain Organization from Hemocytes of the Eastern Oyster (Crassostrea virginica) Is a Receptor for the Protistan Parasite Perkinsus marinus12 , 2007, The Journal of Immunology.

[73]  J. L. Ding,et al.  Diversity in lectins enables immune recognition and differentiation of wide spectrum of pathogens. , 2006, International immunology.

[74]  A. Sureda,et al.  Relation between oxidative stress markers and antioxidant endogenous defences during exhaustive exercise , 2005, Free radical research.

[75]  T. Kepler,et al.  Invertebrate immune systems – not homogeneous, not simple, not well understood , 2004, Immunological reviews.

[76]  E. Lilius,et al.  Respiratory burst activity of rainbow trout (Oncorhynchus mykiss) phagocytes is modulated by antimicrobial drugs , 2002 .

[77]  E. Lilius,et al.  Effect of florfenicol on the immune response of rainbow trout (Oncorhynchus mykiss). , 1999, Veterinary immunology and immunopathology.

[78]  S. Rodrigues,et al.  Rainbow trout (Oncorhynchus mykiss) pro-oxidant and genotoxic responses following acute and chronic exposure to the antibiotic oxytetracycline , 2016, Ecotoxicology.

[79]  X. Chai,et al.  Effect of Chronic Sublethal Exposure of Major Heavy Metals on Filtration Rate, Sex Ratio, and Gonad Development of a Bivalve Species , 2013, Bulletin of Environmental Contamination and Toxicology.

[80]  Zhang Zhenguo,et al.  Morphological,structural characteristics and phagocytic and enzymatic activities of haemocytes in blood clam Tegillarca granosa , 2011 .

[81]  Kwang-Sik Choi,et al.  Analysis of EST and lectin expressions in hemocytes of Manila clams (Ruditapes philippinarum) (Bivalvia: Mollusca) infected with Perkinsus olseni. , 2006, Developmental and comparative immunology.