Unique Properties of Cardiac Action Potentials Recorded with Voltage‐Sensitive Dyes

Unique Properties of Optical Action Potentials. Introduction: Optical mapping with voltage‐sensitive dyes has made it possible to record cardiac action potentials with high spatial resolution that is unattainable by conventional techniques. Optically recorded signals possess distinct properties that differ importantly from electrograms recorded with extracellular electrodes or action potentials recorded with microelectrode techniques. Despite the growing application of optical mapping to cardiac electrophysiology, relatively little quantitative information is available regarding the characteristics of optical action potentials recorded from cardiac tissue.

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