Implantable cardioverter defibrillator shocks are prospective predictors of anxiety.

OBJECTIVES To examine the temporal contingency of anxiety and implantable cardioverter defibrillator (ICD) therapy (anti-tachycardia-pacing and shocks to prevent ventricular tachycardia and/or fibrillation). BACKGROUND It is under debate whether anxiety is a precursor and/or consequence of ICD-therapy. METHODS In a prospective longitudinal study, fifty-four patients undergoing first-time ICD-implantation were assessed for anxiety, frequency of ICD-shocks and anti-tachycardia-pacing up to two days before ICD-implantation (T0) and twelve months later (T1). RESULTS Anxiety at T0 did not predict frequency of ICD-shocks at T1, but ICD-shocks significantly predicted increased anxiety at T1. In contrast, anxiety at T0 and T1 was unrelated to frequency of anti-tachycardia-pacing. Effects remained stable when we controlled for potentially confounding variables (e.g. age, sex, cardiac health and depression at T0). CONCLUSION Our findings indicate that repeated ICD-shocks are a cause of anxiety in ICD-patients rather than a consequence, thus shock frequency should be minimized.

[1]  J Michael Bostwick,et al.  An updated review of implantable cardioverter/defibrillators, induced anxiety, and quality of life. , 2007, The Psychiatric clinics of North America.

[2]  W. Arrindell Phobic dimensions: IV. The structure of animal fears. , 2000, Behaviour research and therapy.

[3]  P. Pauli,et al.  Anxiety in patients with an automatic implantable cardioverter defibrillator: what differentiates them from panic patients? , 1999, Psychosomatic medicine.

[4]  John J. B. Allen,et al.  Cardiac Vagal Tone, defensiveness, and motivational style , 2005, Biological Psychology.

[5]  S. Crow,et al.  Psychopathology following cardioverter defibrillator implantation. , 1998, Psychosomatics.

[6]  C. Murdock,et al.  The Impact of the Implantable Cardioverter Defibrillator on Quality‐of‐Life , 1995, Pacing and clinical electrophysiology : PACE.

[7]  S. Sears,et al.  Measuring Patient Acceptance of Implantable Cardiac Device Therapy: , 2005, Journal of cardiovascular electrophysiology.

[8]  B. Bandelow,et al.  Assessing the efficacy of treatments for panic disorder and agoraphobia. II. The Panic and Agoraphobia Scale , 1995, International clinical psychopharmacology.

[9]  C. Spielberger State‐Trait Anxiety Inventory , 2010 .

[10]  C. Dougherty The natural history of recovery following sudden cardiac arrest and internal cardioverter-defibrillator implantation. , 2001, Progress in cardiovascular nursing.

[11]  Tsuyoshi Suzuki,et al.  Prevalence and Persistence of Depression in Patients with Implantable Cardioverter Defibrillator: A 2‐year Longitudinal Study , 2010, Pacing and clinical electrophysiology : PACE.

[12]  W. Low,et al.  Reliability and validity of the Spielberger State-Trait Anxiety Inventory (STAI) among urological patients: a Malaysian study. , 2004, The Medical journal of Malaysia.

[13]  A. Camm,et al.  Examining the psychosocial impact of implantable cardioverter defibrillators: A literature review , 1999, Clinical cardiology.

[14]  J. Denollet,et al.  Shocks, Personality, and Anxiety in Patients with an Implantable Defibrillator , 2008, Pacing and clinical electrophysiology : PACE.

[15]  A. Moss,et al.  Physical functioning and mental well-being in association with health outcome in patients enrolled in the Multicenter Automatic Defibrillator Implantation Trial II. , 2006, European heart journal.

[16]  H. Wittchen,et al.  SKID. Strukturiertes Klinisches Interview für DSM-IV. Achse I und II. Handanweisung , 1997 .

[17]  A. Mathews,et al.  Brief standard self-rating for phobic patients. , 1979, Behaviour research and therapy.

[18]  J. Bostwick,et al.  Implantable cardioverter-defibrillators, induced anxiety, and quality of life. , 2005, Mayo Clinic proceedings.

[19]  M. Burg,et al.  Psychological Traits and Emotion-Triggering of ICD Shock-Terminated Arrhythmias , 2004, Psychosomatic medicine.

[20]  C. Herrmann-Lingen,et al.  [Cardiological and psychosocial status of patients with malignant ventricular arrhythmias before implantation of a cardioverter defibrillator. First results from the German Austrian ICD Multicenter Study (GAIMS)]. , 2004, Psychotherapie, Psychosomatik, medizinische Psychologie.

[21]  S. Behrens,et al.  Classic Conditioning and Dysfunctional Cognitions in Patients With Panic Disorder and Agoraphobia Treated With an Implantable Cardioverter/Defibrillator , 2001, Psychosomatic medicine.

[22]  Martin Hautzinger,et al.  Beck Depressions-Inventar , 2006 .

[23]  W. Arrindell,et al.  Phobic dimensions: I. Reliability and generalizability across samples, gender and nations , 1984 .

[24]  R. Keren,et al.  Anxiety and Depression in Patients with Life‐Threatening Ventricular Arrhythmias: Impact of the Implantable Cardioverter‐Defibrillator , 1991, Pacing and clinical electrophysiology : PACE.

[25]  P. Pauli,et al.  Stability and cause of anxiety in patients with an implantable cardioverter-defibrillator: a longitudinal two-year follow-up. , 2007, Heart & lung : the journal of critical care.

[26]  B. Riegel,et al.  Persistent comorbid symptoms of depression and anxiety predict mortality in heart disease. , 2010, International Journal of Cardiology.

[27]  C. Rinaldi,et al.  Device therapy for the management of cardiac tachyarrhythmias , 2010, Expert review of cardiovascular therapy.

[28]  E. Sigurdsson,et al.  Health-related quality of life of patients with implantable cardioverter defibrillators compared with that of pacemaker recipients. , 2006, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[29]  A. Beck,et al.  Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients. , 1996, Journal of personality assessment.

[30]  R. Sciacca,et al.  Psychosocial Outcome after ICD Implantation: A Current Perspective , 1998, Pacing and clinical electrophysiology : PACE.

[31]  J. Beck,et al.  Assessing older adults with generalized anxiety: a replication and extension. , 2001, Behaviour research and therapy.

[32]  S. Pedersen,et al.  Shock as a Determinant of Poor Patient‐Centered Outcomes in Implantable Cardioverter Defibrillator Patients: Is There More to It Than Meets the Eye? , 2010, Pacing and clinical electrophysiology : PACE.

[33]  C. Herrmann,et al.  Standardized Assessment of Psychological Well‐Being and Quality‐of‐Life in Patients with Implanted Defibrillators , 1997, Pacing and clinical electrophysiology : PACE.

[34]  C. Dougherty,et al.  Predictors of Implantable Cardioverter Defibrillator Shocks During the First Year , 2009, The Journal of cardiovascular nursing.

[35]  A. Beck,et al.  An inventory for measuring clinical anxiety: psychometric properties. , 1988, Journal of consulting and clinical psychology.

[36]  B. Lüderitz,et al.  Patient acceptance of implantable cardioverter defibrillator devices: changing attitudes. , 1994, American heart journal.

[37]  K. Adalet,et al.  Depression and Anxiety Status of Patients with Implantable Cardioverter Defibrillator and Precipitating Factors , 2006, Pacing and clinical electrophysiology : PACE.

[38]  Brian Baker,et al.  Quality of life in the Canadian Implantable Defibrillator Study (CIDS). , 2002, American heart journal.

[39]  T. Sensky,et al.  How different from pacemaker patients are recipients of implantable cardioverter-defibrillators with respect to psychosocial adaptation, affective disorders, and quality of life? , 2001, Heart.

[40]  A. Kirkness,et al.  Avoidance behaviors in patients with implantable cardioverter defibrillators. , 2004, Heart & lung : the journal of critical care.

[41]  U. Feske,et al.  Convergent and divergent validity of the Beck Anxiety Inventory for patients with panic disorder and agoraphobia , 1997, Depression and anxiety.

[42]  R. Passman,et al.  Implantable cardioverter defibrillators and quality of life: results from the defibrillators in nonischemic cardiomyopathy treatment evaluation study. , 2007, Archives of Internal Medicine.

[43]  J. Langberg,et al.  Association of mood disturbance and arrhythmia events in patients after cardioverter defibrillator implantation , 1999, Depression and anxiety.

[44]  R. Hauer,et al.  Implantable cardioverter defibrillator recipients: quality of life in recipients with and without ICD shock delivery: a prospective study. , 2003, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[45]  K. Fritzsche,et al.  Kardiologische und psychosoziale Befunde bei Patienten mit malignen ventrikulären Herzrhythmusstörungen vor Implantation eines internen Defibrillators : erste Ergebnisse aus der deutsch-österreichischen Multizenterstudie zu Krankheitserleben und -verlauf bei Patienten mit implantiertem Defibrillator , 2004 .

[46]  Edgar Erdfelder,et al.  Zur Bedeutung und Kontrolle des ß-Fehlers bei der inferenzstatistischen Prüfung log-linearer Modelle1 , 1984, 1984.

[47]  Wan Ariffin Bin Abdullah,et al.  Med J Malaysia , 2001 .

[48]  M. Hegel,et al.  Anxiety and Depression in Patients Receiving Implanted Cardioverter-Defibrillators: A Longitudinal Investigation , 1997, International journal of psychiatry in medicine.

[49]  D. Carroll,et al.  Quality of life in implanted cardioverter defibrillator recipients: the impact of a device shock. , 2005, Heart & lung : the journal of critical care.

[50]  H. Swartz,et al.  Diagnosis of nonpsychotic patients in community clinics. , 2000, The American journal of psychiatry.

[51]  A. Beck,et al.  Beck Depression Inventory–II , 2011 .

[52]  W. Jung,et al.  Lebensqualität nach Implantation eines Kardioverters/Defibrillators bei malignen Herzrhythmusstörungen , 2008 .

[53]  D. Clark-Carter,et al.  The psychosocial impact of the implantable cardioverter defibrillator: a meta-analytic review. , 2003, British journal of health psychology.

[54]  S. Pedersen,et al.  Psychological Intervention Following Implantation of an Implantable Defibrillator: A Review and Future Recommendations , 2007, Pacing and clinical electrophysiology : PACE.

[55]  B. Hess,et al.  Could implantable cardioverter defibrillators provide a human model supporting the learned helplessness theory of depression? , 1999, General hospital psychiatry.