Case–Control Study, Nested †

Nested case–control studies refer to a class of cohort sampling designs used in epidemiologic research. This article describes the general principles, analysis methods, statistical properties, and relationship to other approaches. Methods are illustrated by studies from the epidemiological literature. Keywords: case–control studies; cohort studies; failure time data; epidemiology; martingales; matching; partial likelihood; proportional hazards model; sampling; stochastic processes

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