p53 and stem cells: new developments and new concerns.
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[1] Yang Xu,et al. Modeling disease in human ESCs using an efficient BAC-based homologous recombination system. , 2010, Cell stem cell.
[2] O. Gaidarenko,et al. Transcription activity is required for p53-dependent tumor suppression , 2009, Oncogene.
[3] Wenbo Zhou,et al. Adenoviral Gene Delivery Can Reprogram Human Fibroblasts to Induced Pluripotent Stem Cells , 2009, Stem cells.
[4] Justin C. Grindley,et al. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery , 2009, Nature Reviews Drug Discovery.
[5] R. Weinberg,et al. Cancer stem cells: mirage or reality? , 2009, Nature Medicine.
[6] Manuel Serrano,et al. A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity , 2009, Nature.
[7] M. Blasco,et al. The Ink4/Arf locus is a barrier for iPS cell reprogramming , 2009, Nature.
[8] J. Utikal,et al. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells , 2009, Nature.
[9] T. Ichisaka,et al. Suppression of induced pluripotent stem cell generation by the p53–p21 pathway , 2009, Nature.
[10] Ge Guo,et al. Nanog Is the Gateway to the Pluripotent Ground State , 2009, Cell.
[11] G. Wahl,et al. Linking the p53 tumor suppressor pathway to somatic cell reprogramming , 2009, Nature.
[12] G. Daley,et al. A role for Lin28 in primordial germ cell development and germ cell malignancy , 2009, Nature.
[13] Mike J. Mason,et al. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. , 2009, Cell stem cell.
[14] Robert Lanza,et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. , 2009, Cell stem cell.
[15] Wei Gu,et al. Modes of p53 Regulation , 2009, Cell.
[16] R. Stewart,et al. Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences , 2009, Science.
[17] Dong Wook Han,et al. Generation of induced pluripotent stem cells using recombinant proteins. , 2009, Cell stem cell.
[18] C. Prives,et al. Blinded by the Light: The Growing Complexity of p53 , 2009, Cell.
[19] A. Trounson. Rats, cats, and elephants, but still no unicorn: induced pluripotent stem cells from new species. , 2009, Cell stem cell.
[20] Xiaolei Yin,et al. Two supporting factors greatly improve the efficiency of human iPSC generation. , 2008, Cell stem cell.
[21] Yang Xu,et al. Induction of genetic instability by gain-of-function p53 cancer mutants , 2008, Oncogene.
[22] G. Daley,et al. Selective Blockade of MicroRNA Processing by Lin28 , 2008, Science.
[23] Shulan Tian,et al. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.
[24] A. Levine,et al. p53 regulates maternal reproduction through LIF , 2007, Nature.
[25] T. Ichisaka,et al. Generation of germline-competent induced pluripotent stem cells , 2007, Nature.
[26] T. Stiewe,et al. The p53 family in differentiation and tumorigenesis , 2007, Nature Reviews Cancer.
[27] E. Appella,et al. Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage , 2006, Molecular and Cellular Biology.
[28] S. Yamanaka,et al. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.
[29] D. Herr,et al. Ser18 and 23 phosphorylation is required for p53‐dependent apoptosis and tumor suppression , 2006, The EMBO journal.
[30] E. Perez,et al. New therapies in the treatment of breast cancer. , 2006, Seminars in oncology.
[31] Wei Gu,et al. p53 ubiquitination: Mdm2 and beyond. , 2006, Molecular cell.
[32] D. Peeper,et al. KLF4, p21 and context-dependent opposing forces in cancer , 2006, Nature Reviews Cancer.
[33] A. Hart,et al. The pluripotency homeobox gene NANOG is expressed in human germ cell tumors , 2005, Cancer.
[34] A. Clark,et al. Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma , 2005, Cancer.
[35] U. Moll,et al. Stress-induced p53 runs a transcription-independent death program. , 2005, Biochemical and biophysical research communications.
[36] A. Strasser,et al. Death squads enlisted by the tumour suppressor p53. , 2005, Biochemical and biophysical research communications.
[37] Rudolf Jaenisch,et al. Ectopic Expression of Oct-4 Blocks Progenitor-Cell Differentiation and Causes Dysplasia in Epithelial Tissues , 2005, Cell.
[38] Ettore Appella,et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression , 2005, Nature Cell Biology.
[39] A. Giaccia,et al. The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality , 2005, Nature Genetics.
[40] M. Oshimura,et al. Generation of Pluripotent Stem Cells from Neonatal Mouse Testis , 2004, Cell.
[41] Austin G Smith,et al. Self-renewal of teratocarcinoma and embryonic stem cells , 2004, Oncogene.
[42] Christian Schwager,et al. Embryonic Stem Cell-Like Features of Testicular Carcinoma in Situ Revealed by Genome-Wide Gene Expression Profiling , 2004, Cancer Research.
[43] S. Sell,et al. Stem cell origin of cancer and differentiation therapy. , 2004, Critical reviews in oncology/hematology.
[44] A. Sancar,et al. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. , 2004, Annual review of biochemistry.
[45] E. Appella,et al. Cell Type- and Promoter-specific Roles of Ser18 Phosphorylation in Regulating p53 Responses* , 2003, Journal of Biological Chemistry.
[46] Y. Sasai,et al. Pluripotency of reprogrammed somatic genomes in embryonic stem hybrid cells , 2003, Developmental dynamics : an official publication of the American Association of Anatomists.
[47] M. Murakami,et al. The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells , 2003, Cell.
[48] J. Nichols,et al. Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells , 2003, Cell.
[49] Yang Xu,et al. Regulation of p53 responses by post-translational modifications , 2003, Cell Death and Differentiation.
[50] Stella Pelengaris,et al. c-MYC: more than just a matter of life and death , 2002, Nature Reviews Cancer.
[51] J. Stringer,et al. Embryonic stem cells and somatic cells differ in mutation frequency and type , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[52] Norio Nakatsuji,et al. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells , 2001, Current Biology.
[53] E. Appella,et al. Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[54] E. Appella,et al. p53 transcriptional activity is essential for p53‐dependent apoptosis following DNA damage , 2000, The EMBO journal.
[55] G. Wahl,et al. A transactivation-deficient mouse model provides insights into Trp53 regulation and function , 2000, Nature Genetics.
[56] M. Roussel,et al. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. , 1999, Genes & development.
[57] G. Wahl,et al. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage , 1998, Current Biology.
[58] I. Wilmut,et al. "Viable Offspring Derived from Fetal and Adult Mammalian Cells" (1997), by Ian Wilmut et al. , 2014 .
[59] B. Vogelstein,et al. p53 mutations in human cancers. , 1991, Science.
[60] R. Briggs,et al. Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs' Eggs. , 1952, Proceedings of the National Academy of Sciences of the United States of America.