Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene.

[1]  E. Fuchs,et al.  Targeted p120-Catenin Ablation Disrupts Dental Enamel Development , 2010, PloS one.

[2]  H. Moses,et al.  Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. , 2010, Cancer research.

[3]  S. Bicciato,et al.  Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. , 2010, Immunity.

[4]  M. Washington,et al.  p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. , 2010, The Journal of clinical investigation.

[5]  L. Coussens,et al.  Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity , 2010, Cancer and Metastasis Reviews.

[6]  M. Ikura,et al.  Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion , 2010, Cell.

[7]  N. Ferrara.  Role of myeloid cells in vascular endothelial growth factor-independent tumor angiogenesis , 2010, Current opinion in hematology.

[8]  Luigi Naldini,et al.  FcRgamma activation regulates inflammation-associated squamous carcinogenesis. , 2010, Cancer cell.

[9]  A. Regev,et al.  SOX2 Is an Amplified Lineage Survival Oncogene in Lung and Esophageal Squamous Cell Carcinomas , 2009, Nature Genetics.

[10]  L. Coussens,et al.  CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. , 2009, Cancer cell.

[11]  S. Mocellin,et al.  IL4Rα+ Myeloid-Derived Suppressor Cell Expansion in Cancer Patients1 , 2009, The Journal of Immunology.

[12]  S. Denmeade,et al.  Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin , 2009, Molecular Cancer Therapeutics.

[13]  Srinivas Nagaraj,et al.  Myeloid-derived suppressor cells as regulators of the immune system , 2009, Nature Reviews Immunology.

[14]  G. Bhagat,et al.  Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. , 2008, Cancer cell.

[15]  J. Tobias,et al.  Cdx1 and c-Myc Foster the Initiation of Transdifferentiation of the Normal Esophageal Squamous Epithelium toward Barrett's Esophagus , 2008, PloS one.

[16]  H. Pasolli,et al.  Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer , 2008, Proceedings of the National Academy of Sciences.

[17]  D. Carbone,et al.  Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. , 2008, Cancer cell.

[18]  D. Tuveson,et al.  Dynamics of the immune reaction to pancreatic cancer from inception to invasion. , 2007, Cancer research.

[19]  E. Sahai,et al.  p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism , 2007, Oncogene.

[20]  J. Settleman,et al.  p120-Catenin and p190RhoGAP Regulate Cell-Cell Adhesion by Coordinating Antagonism between Rac and Rho , 2006, Cell.

[21]  Paolo Serafini,et al.  Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. , 2006, The Journal of clinical investigation.

[22]  Raghu Kalluri,et al.  Fibroblasts in cancer , 2006, Nature Reviews Cancer.

[23]  H. Pasolli,et al.  p120-Catenin Mediates Inflammatory Responses in the Skin , 2006, Cell.

[24]  J. Pollard,et al.  Distinct role of macrophages in different tumor microenvironments. , 2006, Cancer research.

[25]  V. Bronte,et al.  Regulation of immune responses by L-arginine metabolism , 2005, Nature Reviews Immunology.

[26]  P. Sinha,et al.  Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease1 , 2005, The Journal of Immunology.

[27]  A. Reynolds,et al.  Emerging roles for p120-catenin in cell adhesion and cancer , 2004, Oncogene.

[28]  B. Fingleton,et al.  Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. , 2004, Cancer cell.

[29]  P. Vincent,et al.  Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells , 2003, The Journal of cell biology.

[30]  Albert B. Reynolds,et al.  A core function for p120-catenin in cadherin turnover , 2003, The Journal of cell biology.

[31]  Hiroshi Nakagawa,et al.  Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation. , 2003, Molecular cancer research : MCR.

[32]  V. Bronte,et al.  L-arginine metabolism in myeloid cells controls T-lymphocyte functions. , 2003, Trends in immunology.

[33]  M. Herlyn,et al.  Epidermal Growth Factor Receptor Mediates Increased Cell Proliferation, Migration, and Aggregation in Esophageal Keratinocytes in Vitro and in Vivo * , 2003, The Journal of Biological Chemistry.

[34]  A. Reynolds,et al.  Altered expression of the catenin p120 in human cancer: implications for tumor progression. , 2002, Differentiation; research in biological diversity.

[35]  F. van Roy,et al.  A novel role for p120 catenin in E-cadherin function , 2002, The Journal of cell biology.

[36]  N. Sharpless,et al.  A mouse model of human oral-esophageal cancer. , 2002, The Journal of clinical investigation.

[37]  D. Gabrilovich,et al.  Mechanism of Immune Dysfunction in Cancer Mediated by Immature Gr-1+ Myeloid Cells1 , 2001, The Journal of Immunology.

[38]  M. Birnbaum,et al.  Akt/Protein Kinase B Isoforms Are Differentially Regulated by Epidermal Growth Factor Stimulation* , 2000, The Journal of Biological Chemistry.

[39]  Yi Zheng,et al.  Inhibition of RhoA by p120 catenin , 2000, Nature Cell Biology.

[40]  F. Brembeck,et al.  The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice. , 2000, Gastroenterology.

[41]  D. Botstein,et al.  Cluster analysis and display of genome-wide expression patterns. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[42]  A. Rustgi,et al.  The targeting of the cyclin D1 oncogene by an Epstein-Barr virus promoter in transgenic mice causes dysplasia in the tongue, esophagus and forestomach , 1997, Oncogene.

[43]  W. Birchmeier,et al.  E-cadherin as a tumor (invasion) suppressor gene. , 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.

[44]  P. Baeuerle,et al.  NF-kappa B as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor gene , 1990, Molecular and cellular biology.

[45]  Y. Shintani,et al.  The regulatory or phosphorylation domain of p120 catenin controls E-cadherin dynamics at the plasma membrane. , 2008, Experimental cell research.

[46]  F. van Roy,et al.  Diverse functions of p120ctn in tumors. , 2007, Biochimica et biophysica acta.

[47]  F.R.A.C.S. F.A.C.S. John Wong Ph.D.,et al.  Altered E-Cadherin Expression and p120 Catenin Localization in Esophageal Squamous Cell Carcinoma , 2007, Annals of Surgical Oncology.

[48]  A. Reynolds,et al.  Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. , 2006, Developmental cell.