Identification of an Antifungal Substance Derived from the Oil-Based Extract of Licorice

Since the oil-based extract of licorice (Glycyrrhiza glabra L.) (OEL) has been found to have high fungicidal effect against Arthrinium sacchari M001 and Chaetomium funicola M002, we studied the structure of an antifungal substance derived from OEL which showed effectiveness against the above two filamentous fungi. Consequently, glabridin (glabridin, 3-(2', 4'-dihydroxyphenyl)-8-dimethylpyrano [8, 7-e] chroman) was found to be an antifungal component in the OEL and its fungicidal effect was confirmed. In order to prevent fungicaused spoilage, the possibility of adding glabridin or a licorice preparation made from OEL to tea beverages was suggested.

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