Double trouble: Mediastinal lymph nodal tuberculosis complicated by amyloidosis and esophago-nodal fistula after endoscopic ultrasound fine-needle aspiration

possibility of amyloidosis in patients with tuberculosis.[3] The diagnosis of secondary amyloidosis portends a grave prognosis and treatment is usually supportive. The occurrence of secondary amyloidosis with concomitant mediastinal lymph nodal tuberculosis is uncommon. Further, the case highlights the possible complication of EUS‐guided tissue acquisition. EUS has emerged as an important tool for the evaluation of mediastinal lymph nodes and the diagnosis of esophageal tuberculosis where the subcarinal lymph node is most commonly involved. To the best of our knowledge, esophago‐nodal fistula has not previously described as a complication of EUS‐guided FNA of tubercular subcarinal lymph node although esophago‐nodal fistulization and mediastinitis have been reported after EUS‐FNA from malignant lymphadenopathy.[4,5]

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[2]  M. Boomsma,et al.  Esophageal fistula after EUS-FNA in a patient treated with bevacizumab for non-small-cell lung cancer. , 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[3]  L. Dave,et al.  Clinical profile of patients having pulmonary tuberculosis and renal amyloidosis , 2009, Lung India : official organ of Indian Chest Society.

[4]  J. Aerts,et al.  EUS-FNA of enlarged necrotic lymph nodes may cause infectious mediastinitis. , 2008, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[5]  P. Malhotra,et al.  How long does it take for tuberculosis to cause secondary amyloidosis? , 2005, European journal of internal medicine.