Biosynthetic flexibility of Pseudomonas aeruginosa leads to hydroxylated 2-alkylquinolones with proinflammatory host response

[1]  T. Böttcher,et al.  Synthesis of Bacterial 2-Alkyl-4(1H)-quinolone Derivatives , 2021 .

[2]  S. Molin,et al.  Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis , 2020, Nature Reviews Microbiology.

[3]  F. Huang,et al.  Beneficial effect of probiotics on Pseudomonas aeruginosa–infected intestinal epithelial cells through inflammatory IL-8 and antimicrobial peptide human beta-defensin-2 modulation , 2020, Innate immunity.

[4]  Diana A. Zaleta-Pinet,et al.  Isolation of 2-Alkyl-4-quinolones with Unusual Side Chains from a Chinese Pseudomonas aeruginosa Isolate. , 2020, Journal of natural products.

[5]  E. Greenberg,et al.  Evolution of the Pseudomonas aeruginosa quorum-sensing hierarchy , 2019, Proceedings of the National Academy of Sciences.

[6]  Juanli Cheng,et al.  The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore , 2018, Front. Cell. Infect. Microbiol..

[7]  W. Blankenfeldt,et al.  The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH‐like 2‐Heptyl‐3‐hydroxy‐4(1H)‐quinolone (PQS) Biosynthesis Enzyme PqsBC , 2018, Chembiochem : a European journal of chemical biology.

[8]  T. Böttcher,et al.  An Unsaturated Quinolone N-Oxide of Pseudomonas aeruginosa Modulates Growth and Virulence of Staphylococcus aureus. , 2017, Angewandte Chemie.

[9]  F. Lépine,et al.  HHQ and PQS, two Pseudomonas aeruginosa quorum‐sensing molecules, down‐regulate the innate immune responses through the nuclear factor‐κB pathway , 2010, Immunology.

[10]  P. Zeitlin,et al.  Down-regulation of IL-8 expression in human airway epithelial cells through helper-dependent adenoviral-mediated RNA interference , 2005, Cell Research.

[11]  L. Rahme,et al.  Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa , 2004, Journal of the American Society for Mass Spectrometry.

[12]  T. A. Springer,et al.  IL-8 Production in Human Lung Fibroblasts and Epithelial Cells Activated by the Pseudomonas Autoinducer N-3-Oxododecanoyl Homoserine Lactone Is Transcriptionally Regulated by NF-κB and Activator Protein-21 , 2001, The Journal of Immunology.

[13]  M. Pirrung,et al.  Pentadienylnitrobenzyl and Pentadienylnitropiperonyl Photochemically Removable Protecting Groups. , 1999, The Journal of organic chemistry.

[14]  J. Golden,et al.  Pseudomonas stimulates interleukin-8 mRNA expression selectively in airway epithelium, in gland ducts, and in recruited neutrophils. , 1994, American journal of respiratory cell and molecular biology.

[15]  Miguel Cámara,et al.  The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment. , 2007, Chemistry & biology.

[16]  O. Park,et al.  Synthesis of 4‐hydroxyquinolin‐2(1H)‐one analogues and 2‐substituted quinolone derivatives , 2001 .

[17]  G. Mann,et al.  Synthese substituierter N‐Hydroxylactame, Lactame, Chinolin‐N‐oxide und Chinoline durch katalysierte Reduktive Cyclisierung von 2‐Nitrocinnamoyl‐Verbindungen mit Wasserstoff/Platinschwarz , 1987 .