Pancreatic enzymes for exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery

The aim of the present study was to evaluate the efficacy and safety of pancreatic enzymes on patients with chronic pancreatitis or pancreatic surgery.

[1]  N. Reddy,et al.  Randomised clinical trial: the efficacy and safety of pancreatin enteric-coated minimicrospheres (Creon 40000 MMS) in patients with pancreatic exocrine insufficiency due to chronic pancreatitis - a double-blind, placebo-controlled study , 2012, Alimentary pharmacology & therapeutics.

[2]  S. Caras,et al.  A 6‐month, open‐label clinical trial of pancrelipase delayed‐release capsules (Creon) in patients with exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery , 2011, Alimentary pharmacology & therapeutics.

[3]  R. Thieroff-Ekerdt,et al.  Efficacy of a Novel Pancreatic Enzyme Product, EUR-1008 (Zenpep), in Patients With Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis , 2011, Pancreas.

[4]  S. Caras,et al.  Pancrelipase Delayed-Release Capsules (CREON) for Exocrine Pancreatic Insufficiency due to Chronic Pancreatitis or Pancreatic Surgery: A Double-Blind Randomized Trial , 2010, The American Journal of Gastroenterology.

[5]  N. Shafiq,et al.  Pancreatic enzymes for chronic pancreatitis. , 2009, The Cochrane database of systematic reviews.

[6]  J. Dominguez-Munoz,et al.  Pancreatic enzyme therapy for pancreatic exocrine insufficiency , 2007, Current gastroenterology reports.

[7]  M. Safdi,et al.  The Effects of Oral Pancreatic Enzymes (Creon 10 Capsule) on Steatorrhea: A Multicenter, Placebo-controlled, Parallel Group Trial in Subjects With Chronic Pancreatitis , 2006, Pancreas.

[8]  A. Figueiras,et al.  Effect of the administration schedule on the therapeutic efficacy of oral pancreatic enzyme supplements in patients with exocrine pancreatic insufficiency: a randomized, three‐way crossover study , 2005, Alimentary pharmacology & therapeutics.

[9]  I. Ihse,et al.  Pain reduction by an oral pancreatic enzyme preparation in chronic pancreatitis , 1983, Digestive Diseases and Sciences.

[10]  P. Malfertheiner,et al.  Exocrine and endocrine pancreatic insufficiency after pancreatic surgery. , 2004, Best practice & research. Clinical gastroenterology.

[11]  P. Lankisch,et al.  Pancreatic enzyme replacement therapy , 2017 .

[12]  S. O'keefe,et al.  The Exacerbation of Pancreatic Endocrine Dysfunction by Potent Pancreatic Exocrine Supplements in Patients with Chronic Pancreatitis , 2001, Journal of clinical gastroenterology.

[13]  J. Neoptolemos,et al.  Exocrine Pancreatic Function following Pancreatectomy , 1999, Annals of the New York Academy of Sciences.

[14]  J. Neoptolemos,et al.  Outcome of surgery for chronic pancreatitis , 1997, The British journal of surgery.

[15]  M. Taubeneck,et al.  Efficacy of Enzyme Supplementation After Surgery for Chronic Pancreatitis , 1997, Pancreas.

[16]  M. Delhaye,et al.  Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis. , 1996, European journal of gastroenterology & hepatology.

[17]  P. Malfertheiner,et al.  Maldigestion after total gastrectomy is associated with pancreatic insufficiency. , 1996, The American journal of gastroenterology.

[18]  G. Tytgat,et al.  Maldigestion associated with exocrine pancreatic insufficiency: implications of gastrointestinal physiology and properties of enzyme preparations for a cause-related and patient-tailored treatment. , 1995, The American journal of gastroenterology.

[19]  A. Malesci,et al.  No effect of long-term treatment with pancreatic extract on recurrent abdominal pain in patients with chronic pancreatitis. , 1995, Scandinavian journal of gastroenterology.

[20]  J. Meyer,et al.  Treatment of pain with pancreatic extracts in chronic pancreatitis: results of a prospective placebo-controlled multicenter trial. , 1992, Digestion.

[21]  P. Lankisch.  [Chronic pancreatitis]. , 1991, Der Internist.

[22]  A. Andrén-sandberg.  Theory and practice in the individualization of oral pancreatic enzyme administration for chronic pancreatitis. , 1989, International journal of pancreatology : official journal of the International Association of Pancreatology.

[23]  B. Lembcke,et al.  Therapy of pancreatogenic steatorrhoea: does acid protection of pancreatic enzymes offer any advantage? , 1986, Zeitschrift fur Gastroenterologie.

[24]  N. T. Pedersen,et al.  Symptomatic effect of pancreatic enzyme therapy in patients with chronic pancreatitis. , 1986, Scandinavian journal of gastroenterology.