Biomimicry patterning with nanosphere suspensions

Experiments designed to mimic cell receptor structures on biomaterial surfaces showed that slow evaporation of water-based suspensions containing polystyrene nanospheres created translucent nanostructured films enclosed by highly regular ring shaped patterns. Our finding represents a novel method to functionalize biomaterial surfaces by structurizing both the micro- and nanoscale topography in one single process, answering practically the complete scale of biological demands required for a better integration of biomaterials into the targeted site of the body.