Synergistic Control of Hand Muscles Through Common Neural Input

Skilled grasping and manipulation rely on spatial and temporal coordination of multiple hand muscles. This chapter describes the phenomenon of common neural input to hand muscles as one of the mechanisms through which the Central Nervous system might coordinate the neural activation of groups of hand muscles acting on a single or multiple digits. The heterogeneous distribution of common input to intrinsic and extrinsic hand muscles is discussed in relation to its functional role for the coordination of hand muscles.

[1]  David M. Halliday,et al.  Weak, Stochastic Temporal Correlation of Large-Scale Synaptic Input Is a Major Determinant of Neuronal Bandwidth , 2000, Neural Computation.

[2]  M. Santello,et al.  Force synergies for multifingered grasping: effect of predictability in object center of mass and handedness , 2002, Experimental Brain Research.

[3]  C. Marsden,et al.  Physiological and pathological tremors and rhythmic central motor control. , 2000, Brain : a journal of neurology.

[4]  Marco Santello,et al.  Role of across-muscle motor unit synchrony for the coordination of forces , 2004, Experimental Brain Research.

[5]  Madeleine M. Lowery,et al.  A Simulation Study to Examine the Effect of Common Motoneuron Inputs on Correlated Patterns of Motor Unit Discharge , 2005, Journal of Computational Neuroscience.

[6]  P H Ellaway,et al.  The source and distribution of short-term synchrony between gamma-motoneurones in the cat. , 1985, Quarterly journal of experimental physiology.

[7]  Zeynep Erim,et al.  Common drive of motor units in regulation of muscle force , 1994, Trends in Neurosciences.

[8]  A. Fuglevand,et al.  Common Input across Motor Nuclei Mediating Precision Grip in Humans , 2005, The Journal of Neuroscience.

[9]  Andrew J Fuglevand,et al.  Motor-unit synchrony within and across compartments of the human flexor digitorum superficialis. , 2007, Journal of neurophysiology.

[10]  R. N. Lemon,et al.  Digital nerve anaesthesia decreases EMG-EMG coherence in a human precision grip task , 2002, Experimental Brain Research.

[11]  F. Zajac,et al.  Large index-fingertip forces are produced by subject-independent patterns of muscle excitation. , 1998, Journal of biomechanics.

[12]  J. F. Soechting,et al.  Force synergies for multifingered grasping , 2000, Experimental Brain Research.

[13]  Michael A. Nordstrom,et al.  Relationship between motor unit short-term synchronization and common drive in human first dorsal interosseous muscle , 1997, Brain Research.

[14]  J. R. Rosenberg,et al.  The Fourier approach to the identification of functional coupling between neuronal spike trains. , 1989, Progress in biophysics and molecular biology.

[15]  M. Hepp-Reymond,et al.  EMG activation patterns during force production in precision grip , 2004, Experimental Brain Research.

[16]  P. Kirkwood On the use and interpretation of cross-correlation measurements in the mammalian central nervous system , 1979, Journal of Neuroscience Methods.

[17]  S C Gandevia,et al.  Selective recruitment of single motor units in human flexor digitorum superficialis muscle during flexion of individual fingers , 2005, The Journal of physiology.

[18]  D. Halliday,et al.  The frequency content of common synaptic inputs to motoneurones studied during voluntary isometric contraction in man. , 1993, The Journal of physiology.

[19]  Hiske van Duinen,et al.  Limited ability to extend the digits of the human hand independently with extensor digitorum , 2009, The Journal of physiology.

[20]  R N Lemon,et al.  Modulation of synchrony between single motor units during precision grip tasks in humans , 2002, The Journal of physiology.

[21]  J. Stephens,et al.  Effect of task on the degree of synchronization of intrinsic hand muscle motor units in man. , 1991, Journal of neurophysiology.

[22]  J. Stephens,et al.  Synchronization of motor unit activity during voluntary contraction in man. , 1990, The Journal of physiology.

[23]  D. Winter,et al.  Models of recruitment and rate coding organization in motor-unit pools. , 1993, Journal of neurophysiology.

[24]  T. M. Hamm,et al.  Influence of fatigue on hand muscle coordination and EMG-EMG coherence during three-digit grasping. , 2010, Journal of neurophysiology.

[25]  Marco Santello,et al.  Coordination and Control of Forces during Multifingered Grasping in Parkinson's Disease , 2002, Experimental Neurology.

[26]  Roger M. Enoka,et al.  Optimization of Input Patterns and Neuronal Properties to Evoke Motor Neuron Synchronization , 2004, Journal of Computational Neuroscience.

[27]  R K Powers,et al.  Relationship between simulated common synaptic input and discharge synchrony in cat spinal motoneurons. , 2001, Journal of neurophysiology.

[28]  T. M. Hamm,et al.  Assessment of across-muscle coherence using multi-unit vs. single-unit recordings , 2010, Experimental Brain Research.

[29]  M. Sale,et al.  Motor unit synchronization measured by cross-correlation is not influenced by short-term strength training of a hand muscle , 2006, Experimental Brain Research.

[30]  L M Harrison,et al.  Organization of inputs to motoneurone pools in man. , 1995, The Journal of physiology.

[31]  A J Fuglevand,et al.  Estimating the strength of common input to human motoneurons from the cross‐correlogram. , 1992, The Journal of physiology.

[32]  M. Santello,et al.  Coordination of intrinsic and extrinsic hand muscle activity as a function of wrist joint angle during two-digit grasping , 2010, Neuroscience Letters.

[33]  Marco Santello,et al.  Task-dependent modulation of multi-digit force coordination patterns. , 2003, Journal of neurophysiology.

[34]  K. Reilly,et al.  Incomplete functional subdivision of the human multitendoned finger muscle flexor digitorum profundus: an electromyographic study. , 2003, Journal of neurophysiology.

[35]  C J De Luca,et al.  Synchronization of motor-unit firings in several human muscles. , 1993, Journal of neurophysiology.

[36]  J A Stephens,et al.  Correlation between the discharges of motor units recorded from the same and from different finger muscles in man. , 1991, The Journal of physiology.

[37]  G. P. Moore,et al.  Neuronal spike trains and stochastic point processes. II. Simultaneous spike trains. , 1967, Biophysical journal.

[38]  Erhard J. Huesler,et al.  EMG activation patterns during force production in precision grip. III. Synchronisation of single motor units , 2000, Experimental Brain Research.

[39]  P. Ellaway,et al.  THE SOURCE AND DISTRIBUTION OF SHORT-TERM SYNCHRONY BETWEEN γ-MOTONEURONES IN THE CAT , 1985 .

[40]  Simon A. Overduin,et al.  Modulation of Muscle Synergy Recruitment in Primate Grasping , 2008, The Journal of Neuroscience.

[41]  Daniel W. Stashuk,et al.  Detection of motor unit action potentials with surface electrodes: influence of electrode size and spacing , 1992, Biological Cybernetics.

[42]  Tara L. McIsaac,et al.  Common synaptic input across motor nuclei supplying intrinsic muscles involved in the precision grip , 2008, Experimental Brain Research.

[43]  S. Gandevia,et al.  A comparison of central aspects of fatigue in submaximal and maximal voluntary contractions. , 2008, Journal of applied physiology.

[44]  R. Enoka,et al.  Quantification of the factors that influence discharge correlation in model motor neurons. , 2004, Journal of neurophysiology.

[45]  J. Stephens,et al.  The reflex responses of single motor units in human first dorsal interosseous muscle following cutaneous afferent stimulation. , 1980, The Journal of physiology.

[46]  T. Sears,et al.  The synaptic connexions to intercostal motoneurones as revealed by the average common excitation potential. , 1978, The Journal of physiology.

[47]  S C Gandevia,et al.  Limits to the control of the human thumb and fingers in flexion and extension. , 2010, Journal of neurophysiology.

[48]  Carlo J De Luca,et al.  Common drive in motor units of a synergistic muscle pair. , 2002, Journal of neurophysiology.

[49]  David Burke,et al.  The Circuitry of the Human Spinal Cord: Its Role in Motor Control and Movement Disorders , 2005 .

[50]  Marc H Schieber,et al.  Short-term synchronization between motor units in different functional subdivisions of the human flexor digitorum profundus muscle. , 2004, Journal of neurophysiology.

[51]  A. McComas,et al.  Cutaneous reflexes in small muscles of the hand , 1973, Journal of neurology, neurosurgery, and psychiatry.

[52]  M. Latash,et al.  Enslaving effects in multi-finger force production , 2000, Experimental Brain Research.

[53]  T. Sears,et al.  Short‐term synchronization of intercostal motoneurone activity. , 1976, The Journal of physiology.

[54]  F. Valero-Cuevas Predictive modulation of muscle coordination pattern magnitude scales fingertip force magnitude over the voluntary range. , 2000, Journal of neurophysiology.

[55]  Marco Santello,et al.  Force-independent distribution of correlated neural inputs to hand muscles during three-digit grasping. , 2010, Journal of neurophysiology.

[56]  François G. Meyer,et al.  Coherence at 16-32 Hz can be caused by short-term synchrony of motor units. , 2005, Journal of neurophysiology.

[57]  Roger N. Lemon THE CIRCUITRY OF THE HUMAN SPINAL CORD: ITS ROLE IN MOTOR CONTROL AND MOVEMENT DISORDERS By Emmanuel Pierrot-Deseilligny and David Burke 2005 Cambridge: Cambridge University Press Price: £110.00 ISBN: 978-0-521-82581-8 , 2006 .

[58]  Shi Zhou,et al.  Motor unit synchronisation is enhanced during slow lengthening contractions of a hand muscle , 2002, The Journal of physiology.

[59]  J. Valls-Solé The circuitry of the human spinal cord: Its role in motor control and movement disorders Pierrot-Deseilligny E, Burke D, editors. Hardback. Cambridge University Press; 2005. 642 p. [ISBN: 13978052182581]. , 2008, Clinical Neurophysiology.

[60]  M. Santello,et al.  Muscle-pair specific distribution and grip-type modulation of neural common input to extrinsic digit flexors. , 2006, Journal of neurophysiology.

[61]  François G. Meyer,et al.  Motor-unit coherence and its relation with synchrony are influenced by training. , 2004, Journal of neurophysiology.

[62]  G. P. Moore,et al.  Statistical analysis and functional interpretation of neuronal spike data. , 1966, Annual review of physiology.

[63]  John G Semmler,et al.  Motor Unit Synchronization and Neuromuscular Performance , 2002, Exercise and sport sciences reviews.

[64]  P Ashby,et al.  Reflex responses in upper limb muscles to cutaneous stimuli. , 1993, The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques.

[65]  Charles M. Gray,et al.  Synchronous oscillations in neuronal systems: Mechanisms and functions , 1994, Journal of Computational Neuroscience.

[66]  A. Fuglevand,et al.  Common input to motor neurons innervating the same and different compartments of the human extensor digitorum muscle. , 2004, Journal of neurophysiology.

[67]  J. R. Rosenberg,et al.  Identification of patterns of neuronal connectivity—partial spectra, partial coherence, and neuronal interactions , 1998, Journal of Neuroscience Methods.

[68]  S. Farmer,et al.  Rhythmicity, synchronization and binding in human and primate motor systems , 1998, The Journal of physiology.

[69]  Tara L. McIsaac,et al.  Influence of tactile afferents on the coordination of muscles during a simulated precision grip , 2006, Experimental Brain Research.

[70]  S C Gandevia,et al.  Thumb and finger forces produced by motor units in the long flexor of the human thumb , 2007, The Journal of physiology.

[71]  N Kakuda,et al.  Common modulation of motor unit pairs during slow wrist movement in man , 1999, The Journal of physiology.

[72]  J A Stephens,et al.  Variation in the degree of synchronization exhibited by motor units lying in different finger muscles in man. , 1991, The Journal of physiology.

[73]  R. Enoka,et al.  Motor-unit coherence during isometric contractions is greater in a hand muscle of older adults. , 2003, Journal of neurophysiology.

[74]  M. Tresch,et al.  The case for and against muscle synergies , 2022 .

[75]  S. Gandevia,et al.  Limited independent flexion of the thumb and fingers in human subjects. , 1994, The Journal of physiology.

[76]  G. P. Moore,et al.  Neuronal spike trains and stochastic point processes. I. The single spike train. , 1967, Biophysical journal.

[77]  Erhard J. Huesler,et al.  Task dependence of muscle synchronization in human hand muscles , 1998, Neuroreport.

[78]  C J De Luca,et al.  Hand dominance and motor unit firing behavior. , 1998, Journal of neurophysiology.

[79]  Madeleine M. Lowery,et al.  Coherence between motor unit discharges in response to shared neural inputs , 2007, Journal of Neuroscience Methods.

[80]  M. Santello,et al.  Periodic modulation of motor-unit activity in extrinsic hand muscles during multidigit grasping. , 2005, Journal of neurophysiology.

[81]  Marco Santello,et al.  Common input to motor units of digit flexors during multi-digit grasping. , 2004, Journal of neurophysiology.

[82]  C. D. De Luca,et al.  Voluntary control of motor units in human antagonist muscles: coactivation and reciprocal activation. , 1987, Journal of neurophysiology.

[83]  Riitta Hari,et al.  Task-Dependent Modulations of Cortical Oscillatory Activity in Human Subjects during a Bimanual Precision Grip Task , 2003, NeuroImage.

[84]  M. Santello,et al.  Common input to motor units of intrinsic and extrinsic hand muscles during two-digit object hold. , 2008, Journal of neurophysiology.