Cost‐effectiveness of measles outbreak intervention strategies

Abstract: In this study, we compared the likely cost‐effectiveness of alternative strategies for controlling a school‐based measles outbreak. The analysis involved assessing the expected costs and number of cases in a school‐based outbreak of measles, with no intervention and with each of six control strategies. The marginal cost per case prevented ranged from $32.90 when only previously unvaccinated school children were offered vaccination to $6795 when vaccination was extended to the siblings of school children aged 6 to 12 months. This study provided further evidence of the cost‐effectiveness of vaccination in outbreak control, and yielded useful information to inform control strategies in the event of a school‐based outbreak. Decisions about which groups of children to aim at and whether to conduct school‐based clinics will be influenced by local circumstances, particularly the baseline measles vaccination rate and the measles attack rate among infants. (Aust N Z J Public Health 1998; 22:126‐32)

[1]  A. Herceg,et al.  An outbreak of measles in a highly immunised population: immunisation status and vaccine efficacy. , 2010, Australian journal of public health.

[2]  P. Hawe.  Measles control: a best-practice challenge in public health. , 2010, Australian journal of public health.

[3]  T. Miles,et al.  An outbreak of measles in the Hunter area of New South Wales. , 2010, Australian journal of public health.

[4]  D. Christie,et al.  Measles immunisation compliance: poor impact of bicentennial measles control campaigns on children under five. , 2010, Australian journal of public health.

[5]  P. Bazeley.  Public and private immunisation services: a comparison of costs. , 2010, Community health studies.

[6]  D. Fleming,et al.  An evaluation of measles revaccination among school-entry-aged children. , 1996, Pediatrics.

[7]  A. Corriveau,et al.  Effectiveness of vaccination at 6 to 11 months of age during an outbreak of measles. , 1996, Pediatrics.

[8]  E. Mendelson,et al.  Decay of maternally derived measles antibody in a highly vaccinated population in southern Israel , 1995, The Pediatric infectious disease journal.

[9]  Louisa R Jorm,et al.  Measles outbreak in western Sydney: Vaccine failure or failure to vaccinate? , 1995, The Medical journal of Australia.

[10]  G. Kearns,et al.  Measles: an historical geography of a major human viral disease from global expansion to local retreat, 1840–1990 , 1995, Medical History.

[11]  De Silva Lm,et al.  Measles susceptibility under one year of age and vaccination strategy. , 1994 .

[12]  L. De Silva,et al.  Measles susceptibility under one year of age and vaccination strategy , 1994, The Medical journal of Australia.

[13]  A Briggs,et al.  Uncertainty in the economic evaluation of health care technologies: the role of sensitivity analysis. , 1994, Health economics.

[14]  A. Scott,et al.  The value of early discharge: dispelling some myths. , 1993, Health policy.

[15]  T. Chey,et al.  The epidemiology of incomplete childhood immunization: An analysis of reported immunization status in outer western Sydney , 1993, Journal of paediatrics and child health.

[16]  N. Pollock,et al.  Propofol is a ‘Safe’ Anaesthetic Agent in Malignant Hyperthermia Susceptible Patients , 1992 .

[17]  T. Tulchinsky,et al.  Costs and benefits of a second measles inoculation of children in Israel, the West Bank, and Gaza. , 1990, Journal of epidemiology and community health.

[18]  E. Mast,et al.  Risk factors for measles in a previously vaccinated population and cost-effectiveness of revaccination strategies. , 1990, JAMA.

[19]  P. Mead,et al.  A school-based measles outbreak: the effect of a selective revaccination policy and risk factors for vaccine failure. , 1990, American journal of epidemiology.

[20]  M. Burgess,et al.  Optimal age for measles and mumps vaccination in Australia , 1990, The Medical journal of Australia.

[21]  S. Wilson.  Methods for the economic evaluation of health care programmes , 1987 .

[22]  A. Hinman,et al.  A cost-effectiveness analysis of measles outbreak control strategies. , 1987, American journal of epidemiology.

[23]  L. Sehulster,et al.  Measles outbreak in a fully immunized secondary-school population. , 1987, The New England journal of medicine.

[24]  S. Leeder,et al.  Costs, Severity of Illness and Outcome in Intensive Care , 1986, Anaesthesia and intensive care.

[25]  F. Black,et al.  Maternally derived measles immunity in era of vaccine-protected mothers. , 1986, The Journal of pediatrics.

[26]  P. Mitchell,et al.  The development of performance and cost indicators for preschool immunisation. , 1986, Archives of disease in childhood.

[27]  J. Koplan,et al.  Benefits, risks and costs of immunization for measles, mumps and rubella. , 1985, American journal of public health.

[28]  E. Zell,et al.  Outbreaks in highly vaccinated populations: implications for studies of vaccine performance. , 1994, American journal of epidemiology.

[29]  Louisa Jorm,et al.  Measles epidemic in Western Sydney , 1994 .

[30]  T. Tulchinsky,et al.  Measles control in developing and developed countries: the case for a two-dose policy. , 1993, Bulletin of the World Health Organization.

[31]  Expanded programme on immunization. An estimate of measles vaccine efficacy in a Canberra primary school. , 1993, Releve epidemiologique hebdomadaire.

[32]  F. Cutts,et al.  The epidemiology of measles. , 1992, World health statistics quarterly. Rapport trimestriel de statistiques sanitaires mondiales.

[33]  S. Robertson,et al.  A million dollar measles outbreak: epidemiology, risk factors, and a selective revaccination strategy. , 1992, Public health reports.

[34]  B. McNeil,et al.  Decision analysis for public health: principles and illustrations. , 1984, Annual review of public health.

[35]  R. Albritton,et al.  Cost-benefits of measles eradication: effects of a federal intervention. , 1978, Policy analysis.

[36]  J. McCormick,et al.  Measles vaccine efficacy determined from secondary attack rates during a severe epidemic. , 1977, The Journal of pediatrics.