Characterization of the Tumor Microenvironment and Tumor–Stroma Interaction by Non-invasive Preclinical Imaging
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[1] Pilar López-Larrubia,et al. Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular pH in rat gliomas shows redistribution of protons away from sites of glycolysis. , 2007, Cancer research.
[2] K. Togashi,et al. Evaluation of Tumor-associated Stroma and Its Relationship with Tumor Hypoxia Using Dynamic Contrast-enhanced CT and (18)F Misonidazole PET in Murine Tumor Models. , 2016, Radiology.
[3] N. Ridgway. The role of phosphatidylcholine and choline metabolites to cell proliferation and survival , 2013, Critical reviews in biochemistry and molecular biology.
[4] Arturo Brunetti,et al. Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice , 2013, BMC Medical Imaging.
[5] W. Heindel,et al. Optical In Vivo Imaging of the Alarmin S100A9 in Tumor Lesions Allows for Estimation of the Individual Malignant Potential by Evaluation of Tumor–Host Cell Interaction , 2015, The Journal of Nuclear Medicine.
[6] C. Betsholtz,et al. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. , 2011, Developmental cell.
[7] R. Gillies,et al. 31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. , 1994, The American journal of physiology.
[8] E. Rofstad,et al. Detection of Different Hypoxic Cell Subpopulations in Human Melanoma Xenografts by Pimonidazole Immunohistochemistry , 2008, Radiation research.
[9] Tristan Barrett,et al. MRI of tumor angiogenesis , 2007, Journal of magnetic resonance imaging : JMRI.
[10] W. E. Farnsworth. Prostate Stroma: Physiology , 1999, The Prostate.
[11] J. Koutcher,et al. High-field small animal magnetic resonance oncology studies , 2014, Physics in medicine and biology.
[12] G. Parker,et al. Imaging Intratumor Heterogeneity: Role in Therapy Response, Resistance, and Clinical Outcome , 2014, Clinical Cancer Research.
[13] M. Papi,et al. Epithelial-Stromal Interactions in Human Breast Cancer: Effects on Adhesion, Plasma Membrane Fluidity and Migration Speed and Directness , 2012, PloS one.
[14] F. Dorkoosh,et al. Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation. , 2016, Journal of controlled release : official journal of the Controlled Release Society.
[15] S. Weinhouse. On respiratory impairment in cancer cells. , 1956, Science.
[16] T. Libermann,et al. A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions. , 2005, Cancer research.
[17] M. Schäfers,et al. Mechanistic interrogation of combination bevacizumab/dual PI3K/mTOR inhibitor response in glioblastoma implementing novel MR and PET imaging biomarkers , 2016, European Journal of Nuclear Medicine and Molecular Imaging.
[18] P. Friedl,et al. The biology of cell locomotion within three-dimensional extracellular matrix , 2000, Cellular and Molecular Life Sciences CMLS.
[19] Ralph Weissleder,et al. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy , 2009, Proceedings of the National Academy of Sciences.
[20] J. Pollard. Tumour-educated macrophages promote tumour progression and metastasis , 2004, Nature Reviews Cancer.
[21] J. Pollard,et al. A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors , 2004, Cancer Research.
[22] Agnes G Loeffler,et al. Periductal stromal collagen topology of pancreatic ductal adenocarcinoma differs from that of normal and chronic pancreatitis , 2015, Modern Pathology.
[23] D. Matei,et al. Tissue Transglutaminase Mediated Tumor–Stroma Interaction Promotes Pancreatic Cancer Progression , 2015, Clinical Cancer Research.
[24] A. Lucas,et al. Tumor Microenvironment Derived Exosomes Pleiotropically Modulate Cancer Cell 1 Metabolism 2 , 2016 .
[25] M. Andreeff,et al. Direct Evidence of Mesenchymal Stem Cell Tropism for Tumor and Wounding Microenvironments Using In Vivo Bioluminescent Imaging , 2009, Stem cells.
[26] R. Mecham. Overview of Extracellular Matrix , 2012, Current protocols in cell biology.
[27] Marina V Shirmanova,et al. Influence of mesenchymal stem cells on metastasis development in mice in vivo , 2015, Stem Cell Research & Therapy.
[28] M. Konopleva,et al. Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment. , 2010, Cytotherapy.
[29] A. Dietz,et al. Mesenchymal Stem Cell Carriers Protect Oncolytic Measles Viruses from Antibody Neutralization in an Orthotopic Ovarian Cancer Therapy Model , 2009, Clinical Cancer Research.
[30] James L Tatum,et al. Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy , 2006, International journal of radiation biology.
[31] M. Neeman,et al. Magnetic resonance imaging visualization of hyaluronidase in ovarian carcinoma. , 2005, Cancer research.
[32] Kwangmeyung Kim,et al. Hyaluronic acid derivative-coated nanohybrid liposomes for cancer imaging and drug delivery. , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[33] M. Mazzone,et al. Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment , 2014, Oncogene.
[34] Timothy Solberg,et al. Correlations of noninvasive BOLD and TOLD MRI with pO2 and relevance to tumor radiation response , 2014, Magnetic resonance in medicine.
[35] S. Arridge,et al. Quantitative spectroscopic photoacoustic imaging: a review. , 2012, Journal of biomedical optics.
[36] Z. Werb,et al. Extracellular matrix degradation and remodeling in development and disease. , 2011, Cold Spring Harbor perspectives in biology.
[37] J. Wrana,et al. Free somatostatin receptor fraction predicts the antiproliferative effect of octreotide in a neuroendocrine tumor model: implications for dose optimization. , 2013, Cancer research.
[38] R. Mason,et al. Developing oxygen-enhanced magnetic resonance imaging as a prognostic biomarker of radiation response. , 2016, Cancer letters.
[39] Barjor Gimi,et al. Molecular and functional imaging of cancer: advances in MRI and MRS. , 2004, Methods in enzymology.
[40] Chelsea S. Kidwell,et al. Imaging of the brain and cerebral vasculature in patients with suspected stroke: Advantages and disadvantages of CT and MRI , 2006, Current neurology and neuroscience reports.
[41] Edward E Graves,et al. Imaging radiation response in tumor and normal tissue. , 2015, American journal of nuclear medicine and molecular imaging.
[42] R. Deberardinis,et al. Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis , 2007, Proceedings of the National Academy of Sciences.
[43] Thomas E. Yankeelov,et al. Practical Dynamic Contrast Enhanced MRI in Small Animal Models of Cancer: Data Acquisition, Data Analysis, and Interpretation , 2012, Pharmaceutics.
[44] E. Lengyel,et al. MicroRNAs as mediators and communicators between cancer cells and the tumor microenvironment , 2015, Oncogene.
[45] L. Blavier,et al. Modifying the soil to affect the seed: role of stromal-derived matrix metalloproteinases in cancer progression , 2006, Cancer and Metastasis Reviews.
[46] Maddy Parsons,et al. Advances in imaging cell–matrix adhesions , 2010, Journal of Cell Science.
[47] J. Galons,et al. Design and application of NMR‐compatible bioreactor circuits for extended perfusion of high‐density mammalian cell cultures , 1993, NMR in biomedicine.
[48] Jianfeng Zeng,et al. A Self‐Assembled Albumin‐Based Nanoprobe for In Vivo Ratiometric Photoacoustic pH Imaging , 2015, Advanced materials.
[49] Rohit Bhargava,et al. Integration of Molecular Profiling and Chemical Imaging to Elucidate Fibroblast-Microenvironment Impact on Cancer Cell Phenotype and Endocrine Resistance in Breast Cancer , 2014, PloS one.
[50] G. Pearson,et al. Breast cancer subtype-specific interactions with the microenvironment dictate mechanisms of invasion. , 2011, Cancer research.
[51] H. Mizukami,et al. Retroviral vector‐producing mesenchymal stem cells for targeted suicide cancer gene therapy , 2009, The journal of gene medicine.
[52] Hyunsuk Shim,et al. Magnetic Resonance Spectroscopic Imaging of Tumor Metabolic Markers for Cancer Diagnosis, Metabolic Phenotyping, and Characterization of Tumor Microenvironment , 2004, Disease markers.
[53] A. Padhani,et al. Therapy Monitoring with Functional and Molecular MR Imaging. , 2016, Magnetic resonance imaging clinics of North America.
[54] M. Kay,et al. Sarcoma Derived from Cultured Mesenchymal Stem Cells , 2007, Stem cells.
[55] P. Dubey. Reporter Gene Imaging of Immune Responses to Cancer: Progress and Challenges , 2012, Theranostics.
[56] R. Deberardinis,et al. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. , 2008, Cell metabolism.
[57] A. Nerlich,et al. Synthesis and degradation of basement membranes and extracellular matrix and their regulation by TGF-beta in invasive carcinomas (Review). , 2001, International journal of oncology.
[58] F. Podo. Tumour phospholipid metabolism , 1999, NMR in biomedicine.
[59] S. Lukyanov,et al. Intracellular pH imaging in cancer cells in vitro and tumors in vivo using the new genetically encoded sensor SypHer2. , 2015, Biochimica et biophysica acta.
[60] Fei Xing,et al. Cancer associated fibroblasts (CAFs) in tumor microenvironment. , 2010, Frontiers in bioscience.
[61] J. Pouysségur,et al. Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters , 2015, Journal of Molecular Medicine.
[62] Z. Werb,et al. Intravital imaging of stromal cell dynamics in tumors. , 2010, Current opinion in genetics & development.
[63] Kinam Park,et al. Hyaluronic acid-based nanocarriers for intracellular targeting: interfacial interactions with proteins in cancer. , 2012, Colloids and surfaces. B, Biointerfaces.
[64] K. Choi,et al. A facile, one-step nanocarbon functionalization for biomedical applications. , 2012, Nano letters.
[65] C. Thng,et al. Fundamentals of tracer kinetics for dynamic contrast‐enhanced MRI , 2011, Journal of magnetic resonance imaging : JMRI.
[66] J. Mi,et al. Metabolic reprogramming of the tumour microenvironment , 2015, The FEBS journal.
[67] K. Shah. Mesenchymal stem cells engineered for cancer therapy. , 2012, Advanced drug delivery reviews.
[68] R. Weissleder,et al. Imaging macrophages with nanoparticles. , 2014, Nature materials.
[69] C. Anderson,et al. Imaging the Tumor Microenvironment. , 2017, Advances in experimental medicine and biology.
[70] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[71] M J Bissell,et al. The influence of the microenvironment on the malignant phenotype. , 2000, Molecular medicine today.
[72] Kenneth A Krohn,et al. F-18 fluoromisonidazole for imaging tumor hypoxia: imaging the microenvironment for personalized cancer therapy. , 2015, Seminars in nuclear medicine.
[73] Xilin Sun,et al. Tumor Hypoxia Imaging , 2011, Molecular Imaging and Biology.
[74] P Peschke,et al. Multimodality imaging of hypoxia in preclinical settings. , 2010, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....
[75] Dan Wu,et al. Contrast Agents for Photoacoustic and Thermoacoustic Imaging: A Review , 2014, International journal of molecular sciences.
[76] K. Anderson,et al. Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anti-cancer drug activity , 2010, Nature Medicine.
[77] P. Chiarugi,et al. Metabolic implication of tumor:stroma crosstalk in breast cancer , 2014, Journal of Molecular Medicine.
[78] J. Condeelis,et al. Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro , 2013, Journal of microscopy.
[79] D. Pang,et al. Quantum dots-based in situ molecular imaging of dynamic changes of collagen IV during cancer invasion. , 2013, Biomaterials.
[80] D. Pang,et al. Coevolution of the tumor microenvironment revealed by quantum dot-based multiplexed imaging of hepatocellular carcinoma. , 2013, Future oncology.
[81] A. Hamilton,et al. Tracking and evaluation of dendritic cell migration by cellular magnetic resonance imaging. , 2013, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.
[82] Valerie A Longo,et al. PET Imaging of Extracellular pH in Tumors with 64Cu- and 18F-Labeled pHLIP Peptides: A Structure–Activity Optimization Study , 2016, Bioconjugate chemistry.
[83] Monitoring of natural killer cell immunotherapy using noninvasive imaging modalities. , 2010, Cancer research.
[84] Kevin W. Eliceiri,et al. Multiphoton microscopy and fluorescence lifetime imaging microscopy (FLIM) to monitor metastasis and the tumor microenvironment , 2008, Clinical & Experimental Metastasis.
[85] L. Matrisian,et al. Imaging matrix metalloproteinases in cancer , 2008, Cancer and Metastasis Reviews.
[86] Sergey Petryakov,et al. In vivo proton-electron double-resonance imaging of extracellular tumor pH using an advanced nitroxide probe. , 2014, Analytical chemistry.
[87] Natarajan Raghunand,et al. In vivo imaging of extracellular pH using 1H MRSI , 1999, Magnetic resonance in medicine.
[88] S. Cerdán,et al. Chemistry of paramagnetic and diamagnetic contrast agents for Magnetic Resonance Imaging and Spectroscopy pH responsive contrast agents. , 2008, European journal of radiology.
[89] M. Pisanu,et al. MR evaluation of response to targeted treatment in cancer cells , 2011, NMR in biomedicine.
[90] Xiaoming Yang,et al. A novel redox-sensitive system based on single-walled carbon nanotubes for chemo-photothermal therapy and magnetic resonance imaging , 2016, International journal of nanomedicine.
[91] M. Kanellaki,et al. Lung carcinoma imaging using a synthetic laminin derivative radioiodinated peptide YIGSR. , 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[92] Jeffrey Wyckoff,et al. Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy , 2005, BMC biotechnology.
[93] Lehui Lu,et al. Multifunctional envelope-type mesoporous silica nanoparticles for pH-responsive drug delivery and magnetic resonance imaging. , 2015, Biomaterials.
[94] Guido Böning,et al. Image-guided, tumor stroma-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated NIS gene delivery. , 2011, Molecular therapy : the journal of the American Society of Gene Therapy.
[95] A. Huang,et al. Utilization of Multiphoton Imaging For Real-Time Fate Determination of Mesenchymal Stem Cells in an Immunocompetent Mouse Model. , 2014, Journal of stem cell research & therapy.
[96] A. Reynolds,et al. Targeting collagen for diagnostic imaging and therapeutic delivery. , 2016, Journal of controlled release : official journal of the Controlled Release Society.
[97] P. Low,et al. Evaluation of Nonpeptidic Ligand Conjugates for SPECT Imaging of Hypoxic and Carbonic Anhydrase IX-Expressing Cancers. , 2016, Bioconjugate chemistry.
[98] Pei-Chun Wu,et al. In vivo Quantification of the Structural Changes of Collagens in a Melanoma Microenvironment with Second and Third Harmonic Generation Microscopy , 2015, Scientific Reports.
[99] F. Sanchez-Garcia,et al. Lactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic Relevance , 2016, Front. Immunol..
[100] Joseph M. Negri,et al. The role of tumour–stromal interactions in modifying drug response: challenges and opportunities , 2013, Nature Reviews Drug Discovery.
[101] I. Hilger,et al. In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes. , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[102] E. Lengyel,et al. Molecular Pathways: Trafficking of Metabolic Resources in the Tumor Microenvironment , 2015, Clinical Cancer Research.
[103] W. Webb,et al. Multiphoton microscopy in biological research. , 2001, Current opinion in chemical biology.
[104] Z. Bhujwalla,et al. Metabolic tumor imaging using magnetic resonance spectroscopy. , 2011, Seminars in oncology.
[105] Jie Tian,et al. Hyaluronic Acid Modified Tantalum Oxide Nanoparticles Conjugating Doxorubicin for Targeted Cancer Theranostics. , 2015, Bioconjugate chemistry.
[106] O. Lee,et al. In Vivo Fluorescence Imaging Reveals the Promotion of Mammary Tumorigenesis by Mesenchymal Stromal Cells , 2013, PloS one.
[107] O Feron,et al. Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force , 2013, Journal of internal medicine.
[108] Hyo-Eon Jin,et al. Collagen mimetic peptide engineered M13 bacteriophage for collagen targeting and imaging in cancer. , 2014, Biomaterials.
[109] Xunbin Wei,et al. Evaluating tumor metastatic potential by imaging intratumoral acidosis via pH‐activatable near‐infrared fluorescent probe , 2015, International journal of cancer.
[110] F. Azuaje,et al. Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma , 2016, Oncotarget.
[111] R. Weinberg,et al. Heterogeneity of stromal fibroblasts in tumors. , 2007, Cancer biology & therapy.
[112] C. Franz,et al. Imaging collagen type I fibrillogenesis with high spatiotemporal resolution. , 2015, Ultramicroscopy.
[113] Sanjiv Sam Gambhir,et al. Molecular Photoacoustic Imaging of Follicular Thyroid Carcinoma , 2013, Clinical Cancer Research.
[114] Z. Werb,et al. Matrix Metalloproteinases: Regulators of the Tumor Microenvironment , 2010, Cell.
[115] E. Turley,et al. Hyaluronan metabolism in remodeling extracellular matrix: probes for imaging and therapy of breast cancer. , 2011, Integrative biology : quantitative biosciences from nano to macro.
[116] Yin Zhang,et al. Molecular Imaging of Proteases in Cancer. , 2009, Cancer growth and metastasis.
[117] Mingwu Shen,et al. Hyaluronic acid-modified hydrothermally synthesized iron oxide nanoparticles for targeted tumor MR imaging. , 2014, Biomaterials.
[118] M. Aumailley,et al. The laminin family , 2013, Cell adhesion & migration.
[119] B. Davidson,et al. Laminin-induced signaling in tumor cells. , 2005, Cancer letters.
[120] M. Pomper,et al. Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides , 2014, Journal of Visualized Experiments.
[121] M. Q. Huang,et al. In vivo MRS markers of response to CHOP chemotherapy in the WSU‐DLCL2 human diffuse large B‐cell lymphoma xenograft , 2008, NMR in biomedicine.
[122] G. J. Yoshida. Metabolic reprogramming: the emerging concept and associated therapeutic strategies , 2015, Journal of Experimental & Clinical Cancer Research.
[123] A. Signore,et al. Imaging T-lymphocytes in inflammatory diseases: a nuclear medicine approach. , 2014, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....
[124] Jun Lin,et al. An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release. , 2015, Biomaterials.
[125] Yong Hu,et al. Hyaluronic acid-modified Fe3O4@Au core/shell nanostars for multimodal imaging and photothermal therapy of tumors. , 2015, Biomaterials.
[126] Shalom Madar,et al. 'Cancer associated fibroblasts'--more than meets the eye. , 2013, Trends in molecular medicine.
[127] E. Aboagye,et al. Positron Emission Tomography Imaging of Tumor Cell Metabolism and Application to Therapy Response Monitoring , 2016, Front. Oncol..
[128] Yana K Reshetnyak,et al. A novel technology for the imaging of acidic prostate tumors by positron emission tomography. , 2009, Cancer research.
[129] E. D. de Vries,et al. CXCR4 inhibition with AMD3100 sensitizes prostate cancer to docetaxel chemotherapy. , 2012, Neoplasia.
[130] P. Lasch,et al. Spatial resolution in infrared microspectroscopic imaging of tissues. , 2006, Biochimica et biophysica acta.
[131] Ick Chan Kwon,et al. pH-controlled gas-generating mineralized nanoparticles: a theranostic agent for ultrasound imaging and therapy of cancers. , 2015, ACS nano.
[132] Kyle M. Jones,et al. Evaluations of Tumor Acidosis Within In Vivo Tumor Models Using Parametric Maps Generated with AcidoCEST MRI , 2015, Molecular Imaging and Biology.
[133] Ian H. Guldner,et al. A journey to uncharted territory: new technical frontiers in studying tumor-stromal cell interactions. , 2015, Integrative biology : quantitative biosciences from nano to macro.
[134] Eun-Kyung Lim,et al. Hyaluronan-modified magnetic nanoclusters for detection of CD44-overexpressing breast cancer by MR imaging. , 2011, Biomaterials.
[135] J. Valette,et al. Experimental strategies for in vivo13C NMR spectroscopy. , 2017, Analytical biochemistry.
[136] D. Ding,et al. Zoledronic acid prevents the tumor-promoting effects of mesenchymal stem cells via MCP-1 dependent recruitment of macrophages , 2015, Oncotarget.
[137] Rakesh K Jain,et al. In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts , 2009, Nature Methods.
[138] Z. Werb,et al. The extracellular matrix: A dynamic niche in cancer progression , 2012, The Journal of cell biology.
[139] N. M. Khazenzon,et al. Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly(beta-L-malic acid). , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[140] M. Troester,et al. Gene Expression Analysis of In Vitro Cocultures to Study Interactions between Breast Epithelium and Stroma , 2011, Journal of biomedicine & biotechnology.
[141] Donald S. Williams,et al. Tissue specific perfusion imaging using arterial spin labeling , 1994, NMR in biomedicine.
[142] Jesús Pacheco-Torres,et al. Dynamic oxygen challenge evaluated by NMR T1 and T2* – insights into tumor oxygenation , 2015, NMR in biomedicine.
[143] S. Mendrinos,et al. The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer , 2012, Cancer biology & therapy.
[144] Xinqing Jiang,et al. Glycosaminoglycan-targeted iron oxide nanoparticles for magnetic resonance imaging of liver carcinoma. , 2014, Materials science & engineering. C, Materials for biological applications.
[145] Weijun Peng,et al. Composition-property relationships in multifunctional hollow mesoporous carbon nanosystems for PH-responsive magnetic resonance imaging and on-demand drug release. , 2015, Nanoscale.
[146] M. Hou,et al. In Vivo Positron Emission Tomography Imaging of Protease Activity by Generation of a Hydrophobic Product from a Noninhibitory Protease Substrate , 2011, Clinical Cancer Research.
[147] Wei Zhang,et al. Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-a glioma model. , 2011, Neoplasia.
[148] S. Cherry,et al. Simultaneous acquisition of multislice PET and MR images: initial results with a MR-compatible PET scanner. , 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[149] Konstantin Nikolaou,et al. Visualization, imaging and new preclinical diagnostics in radiation oncology , 2014, Radiation oncology.
[150] F. Kiessling,et al. Optical tomography of MMP activity allows a sensitive noninvasive characterization of the invasiveness and angiogenesis of SCC xenografts. , 2014, Neoplasia.
[151] A. Brunetti,et al. Molecular imaging of tumor microenvironment: challenges and perspectives. , 2010, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....
[152] Megan C. Garland,et al. A Bright Future for Precision Medicine: Advances in Fluorescent Chemical Probe Design and Their Clinical Application. , 2016, Cell chemical biology.
[153] M. Egeblad,et al. Live Imaging of Drug Responses in the Tumor Microenvironment in Mouse Models of Breast Cancer , 2013, Journal of visualized experiments : JoVE.
[154] L. Soslowsky,et al. Analysis of collagen organization in mouse achilles tendon using high-frequency ultrasound imaging. , 2014, Journal of biomechanical engineering.
[155] James F. Leary,et al. Tumor-targeting hyaluronic acid nanoparticles for photodynamic imaging and therapy. , 2012, Biomaterials.
[156] Atam P Dhawan,et al. Optical Imaging Modalities for Biomedical Applications , 2010, IEEE Reviews in Biomedical Engineering.
[157] B. Fingleton,et al. Moving targets: Emerging roles for MMPs in cancer progression and metastasis. , 2015, Matrix biology : journal of the International Society for Matrix Biology.
[158] Fei Li,et al. Hyaluronan-Based Nanocarriers with CD44-Overexpressed Cancer Cell Targeting , 2014, Pharmaceutical Research.
[159] Cheol-Sang Kim,et al. Hyaluronic acid conjugated superparamagnetic iron oxide nanoparticle for cancer diagnosis and hyperthermia therapy. , 2015, Carbohydrate polymers.
[160] J. Koutcher,et al. Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment. , 2012, Experimental cell research.
[161] Mark Lubberink,et al. Use of H2(15)O-PET and DCE-MRI to measure tumor blood flow. , 2008, The oncologist.
[162] M. Foster,et al. Biological applications of spin pH probes. , 2000, Cellular and molecular biology.
[163] F. Sotgia,et al. Oncogenes induce the cancer-associated fibroblast phenotype: Metabolic symbiosis and “fibroblast addiction” are new therapeutic targets for drug discovery , 2013, Cell cycle.
[164] Pernille R. Jensen,et al. Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate , 2008, Nature.
[165] Yan Li,et al. Cancer-associated fibroblasts provide a suitable microenvironment for tumor development and progression in oral tongue squamous cancer , 2015, Journal of Translational Medicine.
[166] Ming-Wei Wang,et al. Quantum dot-based in situ simultaneous molecular imaging and quantitative analysis of EGFR and collagen IV and identification of their prognostic value in triple-negative breast cancer , 2016, Tumor Biology.
[167] P. Vaupel,et al. Hypoxia in cancer: significance and impact on clinical outcome , 2007, Cancer and Metastasis Reviews.
[168] M. Stevenson,et al. Anemia, tumor hypoxemia, and the cancer patient. , 2005, International journal of radiation oncology, biology, physics.
[169] D. Pang,et al. Patterns of cancer invasion revealed by QDs-based quantitative multiplexed imaging of tumor microenvironment. , 2011, Biomaterials.
[170] Douglas Hanahan,et al. Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment Prospects and Obstacles for Therapeutic Targeting of Function-enabling Stromal Cell Types , 2022 .
[171] D. Engelman,et al. In Vivo pH Imaging with 99mTc-pHLIP , 2012, Molecular Imaging and Biology.
[172] ROHIT BHARGAVA,et al. Infrared Spectroscopic Imaging: The Next Generation , 2012, Applied spectroscopy.
[173] J. H. Park,et al. Polysaccharide-based nanoparticles for theranostic nanomedicine. , 2016, Advanced drug delivery reviews.
[174] J. Segall,et al. Tumor-stroma: In vivo assays and intravital imaging to study cell migration and metastasis. , 2011, Drug discovery today. Disease models.
[175] M. Neeman,et al. Labeling fibroblasts with biotin‐BSA‐GdDTPA‐FAM for tracking of tumor‐associated stroma by fluorescence and MR imaging , 2005, Magnetic resonance in medicine.
[176] J. Cheong,et al. CD44-specific supramolecular hydrogels for fluorescence molecular imaging of stem-like gastric cancer cells. , 2013, Integrative biology : quantitative biosciences from nano to macro.
[177] D. Flieder,et al. MMP-13 In-Vivo Molecular Imaging Reveals Early Expression in Lung Adenocarcinoma , 2015, PloS one.
[178] Jason A Koutcher,et al. Mapping Tumor Hypoxia In Vivo Using Pattern Recognition of Dynamic Contrast-enhanced MRI Data. , 2012, Translational oncology.
[179] R. Nicholson,et al. Pro-metastatic tumor-stroma interactions in breast cancer. , 2012, Future oncology.
[180] Michal Neeman,et al. Imaging aspects of the tumor stroma with therapeutic implications. , 2014, Pharmacology & therapeutics.
[181] I. Kovalszky,et al. Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression , 2015, BMC Cancer.
[182] Hisataka Kobayashi,et al. Rational chemical design of the next generation of molecular imaging probes based on physics and biology: mixing modalities, colors and signals. , 2011, Chemical Society reviews.
[183] F. Sotgia,et al. Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment. , 2011, The international journal of biochemistry & cell biology.
[184] Jorge Ripoll,et al. Fluorescence Molecular Tomography: Principles and Potential for Pharmaceutical Research , 2011, Pharmaceutics.
[185] H. Yercan,et al. Quantification of Total Collagen in Rabbit Tendon by the Sirius Red Method , 1999 .
[186] L. Trümper,et al. Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases. , 2004, Carcinogenesis.
[187] C. Simón,et al. Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivo effects on migration capacity and tumor growth , 2013, BMC Medicine.
[188] Ashutosh Kumar Singh,et al. PET imaging of the immune system: immune monitoring at the whole body level. , 2010, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....
[189] Harrison H Barrett,et al. Mesenchymal Stem Cell‐Mediated Delivery of the Sodium Iodide Symporter Supports Radionuclide Imaging and Treatment of Breast Cancer , 2011, Stem cells.
[190] Claudio Sorio,et al. Infrared spectroscopy and microscopy in cancer research and diagnosis. , 2012, American journal of cancer research.
[191] J. Griffiths,et al. Current issues in the utility of 19F nuclear magnetic resonance methodologies for the assessment of tumour hypoxia. , 2004, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[192] Michael Ingrisch,et al. Tracer-kinetic modeling of dynamic contrast-enhanced MRI and CT: a primer , 2013, Journal of Pharmacokinetics and Pharmacodynamics.
[193] B. K. Swann,et al. PET/MR images acquired with a compact MR-compatible PET detector in a 7-T magnet. , 2007, Radiology.
[194] J. Valliant,et al. Imaging Biomarkers in Immunotherapy , 2016, Biomarkers in cancer.
[195] A Heerschap,et al. Imaging of cellular therapies. , 2010, Advanced drug delivery reviews.
[196] Kazuya Sato,et al. Cell and gene therapy using mesenchymal stem cells (MSCs). , 2008, Journal of autoimmunity.
[197] J. Steyaert,et al. The metabolic cooperation between cells in solid cancer tumors. , 2014, Biochimica et biophysica acta.
[198] R K Jain,et al. Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy. , 1994, Cancer research.
[199] Yanan Liu,et al. The use of pH-sensitive functional selenium nanoparticles shows enhanced in vivo VEGF-siRNA silencing and fluorescence imaging. , 2014, Nanoscale.
[200] G. Murray,et al. Current mechanistic insights into the roles of matrix metalloproteinases in tumour invasion and metastasis , 2015, The Journal of pathology.
[201] Johnson V. John,et al. Tumor homing indocyanine green encapsulated micelles for near infrared and photoacoustic imaging of tumors. , 2016, Journal of biomedical materials research. Part B, Applied biomaterials.
[202] I. Witz. Tumor-microenvironment interactions: dangerous liaisons. , 2008, Advances in cancer research.
[203] B. Tromberg,et al. Imaging cells and extracellular matrix in vivo by using second-harmonic generation and two-photon excited fluorescence , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[204] J R Griffiths,et al. Clinical studies. , 2005, Advances in pharmacology.
[205] J. Gore,et al. A quantitative comparison of the influence of individual versus population‐derived vascular input functions on dynamic contrast enhanced‐MRI in small animals , 2012, Magnetic resonance in medicine.
[206] S. Sebens,et al. The tumor stroma as mediator of drug resistance--a potential target to improve cancer therapy? , 2012, Current pharmaceutical biotechnology.
[207] Sunkuk Kwon,et al. Emerging lymphatic imaging technologies for mouse and man. , 2014, The Journal of clinical investigation.
[208] Zaver M Bhujwalla,et al. Molecular imaging of the tumor microenvironment for precision medicine and theranostics. , 2014, Advances in cancer research.
[209] Takaya Nagasaki,et al. Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth , 2015, Cancers.
[210] Y. Mao,et al. In vivo tracking of superparamagnetic iron oxide nanoparticle-labeled mesenchymal stem cell tropism to malignant gliomas using magnetic resonance imaging. Laboratory investigation. , 2008, Journal of neurosurgery.
[211] K. Tasanen,et al. Collagen XVII expression correlates with the invasion and metastasis of colorectal cancer. , 2015, Human pathology.
[212] Mina J Bissell,et al. The tumor microenvironment is a dominant force in multidrug resistance. , 2012, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[213] Richard D. Vaughan-Jones,et al. Regulation of tumor pH and the role of carbonic anhydrase 9 , 2007, Cancer and Metastasis Reviews.
[214] W. Woodward,et al. Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment. , 2007, Cancer research.
[215] N. Raghunand. Tissue pH measurement by magnetic resonance spectroscopy and imaging. , 2006, Methods in molecular medicine.
[216] R. Gillies,et al. Hypoxia and the presence of human vascular endothelial cells affect prostate cancer cell invasion and metabolism. , 2007, Neoplasia.
[217] Meng Yang,et al. Whole-body subcellular multicolor imaging of tumor-host interaction and drug response in real time. , 2007, Cancer research.
[218] Benjamin J Vakoc,et al. Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging , 2009, Nature Medicine.
[219] Kwangmeyung Kim,et al. Hyaluronic acid-ceramide-based optical/MR dual imaging nanoprobe for cancer diagnosis. , 2012, Journal of controlled release : official journal of the Controlled Release Society.
[220] I. Fidler,et al. The seed and soil hypothesis revisited—The role of tumor‐stroma interactions in metastasis to different organs , 2011, International journal of cancer.
[221] Q. Pankhurst,et al. Magnetic resonance imaging of mesenchymal stem cells homing to pulmonary metastases using biocompatible magnetic nanoparticles. , 2009, Cancer research.
[222] Tristan Barrett,et al. Macromolecular MRI contrast agents for imaging tumor angiogenesis. , 2006, European journal of radiology.
[223] Giuseppe Trapani,et al. Hyaluronic acid and its derivatives in drug delivery and imaging: Recent advances and challenges. , 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[224] Daniela Thorwarth,et al. A kinetic model for dynamic [18F]-Fmiso PET data to analyse tumour hypoxia , 2005, Physics in medicine and biology.
[225] Chulhong Kim,et al. "Smart" gold nanoparticles for photoacoustic imaging: an imaging contrast agent responsive to the cancer microenvironment and signal amplification via pH-induced aggregation. , 2016, Chemical communications.
[226] F. Bénard,et al. PET Imaging of Carbonic Anhydrase IX Expression of HT-29 Tumor Xenograft Mice with (68)Ga-Labeled Benzenesulfonamides. , 2016, Molecular pharmaceutics.
[227] I. S. Omar,et al. Cancer-associated fibroblasts promote endometrial cancer growth via activation of interleukin-6/STAT-3/c-Myc pathway. , 2016, American journal of cancer research.
[228] R G Shulman,et al. 1H homonuclear editing of rat brain using semiselective pulses. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[229] F. Gallagher,et al. Imaging pH with hyperpolarized 13C , 2011, NMR in biomedicine.
[230] T. Zal,et al. Intravital imaging of anti-tumor immune response and the tumor microenvironment , 2010, Seminars in Immunopathology.
[231] Amy L. Oldenburg,et al. Longitudinal Study of Mammary Epithelial and Fibroblast Co-Cultures Using Optical Coherence Tomography Reveals Morphological Hallmarks of Pre-Malignancy , 2012, PloS one.
[232] S. Cherry. The 2006 Henry N. Wagner Lecture: Of mice and men (and positrons)--advances in PET imaging technology. , 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[233] Robert A. Weinberg,et al. Heterogeneity of stromal fibroblasts in tumor , 2007 .
[234] Meng Yang,et al. Activatable near-infrared fluorescent probe for in vivo imaging of fibroblast activation protein-alpha. , 2012, Bioconjugate chemistry.
[235] Lihong V. Wang,et al. Photoacoustic imaging in biomedicine , 2006 .
[236] K. Daoudi,et al. Review of photoacoustic flow imaging: its current state and its promises , 2015, Photoacoustics.
[237] Valerie A Longo,et al. Tumor-Specific Targeting With Modified Sindbis Viral Vectors: Evaluation with Optical Imaging and Positron Emission Tomography In Vivo , 2013, Molecular Imaging and Biology.
[238] Fernando Calamante,et al. The 39 steps: evading error and deciphering the secrets for accurate dynamic susceptibility contrast MRI , 2013, NMR in biomedicine.
[239] D. Le Bihan,et al. Artifacts and pitfalls in diffusion MRI , 2006, Journal of magnetic resonance imaging : JMRI.
[240] Philip S Low,et al. Evaluation of a Carbonic Anhydrase IX-Targeted Near-Infrared Dye for Fluorescence-Guided Surgery of Hypoxic Tumors. , 2016, Molecular pharmaceutics.
[241] B. Toole. Hyaluronan promotes the malignant phenotype. , 2002, Glycobiology.
[242] F. Calamante. Perfusion MRI Using Dynamic-Susceptibility Contrast MRI: Quantification Issues in Patient Studies , 2010, Topics in magnetic resonance imaging : TMRI.
[243] D. V. Von Hoff,et al. Tumor-stroma interactions in pancreatic ductal adenocarcinoma , 2007, Molecular Cancer Therapeutics.
[244] K. Tryggvason,et al. Laminin isoforms in tumor invasion, angiogenesis and metastasis. , 2002, Seminars in cancer biology.
[245] Urs Utzinger,et al. Live imaging of collagen remodeling during angiogenesis. , 2007, American journal of physiology. Heart and circulatory physiology.
[246] C. Thompson,et al. Glutamine addiction: a new therapeutic target in cancer. , 2010, Trends in biochemical sciences.
[247] Z. Bhujwalla,et al. Choline metabolism in malignant transformation , 2011, Nature Reviews Cancer.
[248] L. Themstrup,et al. Imaging of collagen deposition disorders using optical coherence tomography , 2015, Journal of the European Academy of Dermatology and Venereology : JEADV.
[249] John Humm,et al. Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning , 2003, European Journal of Nuclear Medicine and Molecular Imaging.
[250] S. Emelianov,et al. Photoacoustic imaging in cancer detection, diagnosis, and treatment guidance. , 2011, Trends in biotechnology.
[251] C. Radu,et al. In vivo imaging of therapy-induced anti-cancer immune responses in humans , 2012, Cellular and Molecular Life Sciences.
[252] Lin Hou,et al. Tumor-targeted and multi-stimuli responsive drug delivery system for near-infrared light induced chemo-phototherapy and photoacoustic tomography. , 2016, Acta biomaterialia.
[253] P. Opolon,et al. Antitumoral Activity and Osteogenic Potential of Mesenchymal Stem Cells Expressing the Urokinase‐Type Plasminogen Antagonist Amino‐Terminal Fragment in a Murine Model of Osteolytic Tumor , 2008, Stem cells.
[254] Z. Bhujwalla,et al. Choline phospholipid metabolism: A target in cancer cells? , 2003, Journal of cellular biochemistry.
[255] R. Blasberg,et al. Metabolic Plasticity of Metastatic Breast Cancer Cells: Adaptation to Changes in the Microenvironment1 , 2015, Neoplasia.
[256] F. Ganikhanov,et al. Multimodal nonlinear optical imaging of collagen arrays. , 2008, Journal of structural biology.
[257] R. Obeid,et al. The role of choline in prostate cancer. , 2012, Clinical biochemistry.
[258] G. Camussi,et al. Effects of Mesenchymal Stromal Cell-Derived Extracellular Vesicles on Tumor Growth , 2014, Front. Immunol..
[259] Johan Bussink,et al. Dynamics of Tumor Hypoxia Measured with Bioreductive Hypoxic Cell Markers , 2007, Radiation research.
[260] Weian Zhao,et al. To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells , 2013, Oncotarget.
[261] J. Waterton,et al. Correlation of MRI biomarkers with tumor necrosis in Hras5 tumor xenograft in athymic rats. , 2007, Neoplasia.
[262] M. Lepage,et al. A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging. , 2014, Contrast media & molecular imaging.
[263] Hilla Peretz,et al. Ju n 20 03 Schrödinger ’ s Cat : The rules of engagement , 2003 .
[264] Robert Lucht,et al. Tracer kinetic analysis of signal time series from dynamic contrast-enhanced MR imaging , 2006, Biomedizinische Technik. Biomedical engineering.
[265] O. Warburg,et al. THE METABOLISM OF TUMORS IN THE BODY , 1927, The Journal of general physiology.
[266] S. Hung,et al. Mesenchymal Stem Cell Targeting of Microscopic Tumors and Tumor Stroma Development Monitored by Noninvasive In vivo Positron Emission Tomography Imaging , 2005, Clinical Cancer Research.
[267] Byung-Soo Kim,et al. Hyaluronic acid-quantum dot conjugates for in vivo lymphatic vessel imaging. , 2009, ACS nano.
[268] Elise C. Kohn,et al. The microenvironment of the tumour–host interface , 2001, Nature.
[269] Simon R. Cherry,et al. Quantitative, Simultaneous PET/MRI for Intratumoral Imaging with an MRI-Compatible PET Scanner , 2012, The Journal of Nuclear Medicine.
[270] John Kurhanewicz,et al. In vivo hyperpolarized 13C MR spectroscopic imaging with 1H decoupling. , 2009, Journal of magnetic resonance.
[271] C. Hansch,et al. Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. , 2007, Bioorganic & medicinal chemistry.
[272] Sadie M. Johnson,et al. Ultrasound Molecular Imaging of the Breast Cancer Neovasculature using Engineered Fibronectin Scaffold Ligands: A Novel Class of Targeted Contrast Ultrasound Agent , 2016, Theranostics.
[273] R. Xiang,et al. Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model , 2009, PloS one.
[274] Yu-Han H. Hsu,et al. GPU-accelerated nonparametric kinetic analysis of DCE-MRI data from glioblastoma patients treated with bevacizumab. , 2013, Magnetic resonance imaging.
[275] J. Koutcher,et al. In vivo tumor lactate relaxation measurements by selective multiple‐quantum‐coherence (Sel‐MQC) transfer , 2004, Magnetic resonance in medicine.
[276] Barbara Sennino,et al. Labeling Human Mesenchymal Stem Cells with Fluorescent Contrast Agents: the Biological Impact , 2010, Molecular Imaging and Biology.
[277] J. Radosevich,et al. Glutamine at focus: versatile roles in cancer , 2016, Tumor Biology.
[278] P. Friedl,et al. Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response. , 2013, Current opinion in cell biology.
[279] Metabolic interaction between cancer cells and stromal cells according to breast cancer molecular subtype , 2013, Breast Cancer Research.
[280] Sophie Laurent,et al. Classification and basic properties of contrast agents for magnetic resonance imaging. , 2009, Contrast media & molecular imaging.
[281] Amanda C. Freise,et al. In vivo imaging with antibodies and engineered fragments. , 2015, Molecular immunology.
[282] P. Okunieff,et al. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. , 1989, Cancer research.
[283] A. Harris,et al. Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors. , 2015, Cancer Research.
[284] Meng Yang,et al. Dual-color fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[285] Robert M Hoffman,et al. Imaging tumor angiogenesis with fluorescent proteins. , 2004, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[286] Michal Neeman,et al. In vivo imaging of the systemic recruitment of fibroblasts to the angiogenic rim of ovarian carcinoma tumors. , 2007, Cancer research.
[287] W van Elmpt,et al. Characterization of tumor heterogeneity using dynamic contrast enhanced CT and FDG-PET in non-small cell lung cancer. , 2013, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
[288] Dennis C. Sgroi,et al. Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion , 2005, Cell.
[289] Z. Lee,et al. Emerging therapeutic approaches for multipotent mesenchymal stromal cells , 2010, Current opinion in hematology.
[290] S. Turley,et al. Immunological hallmarks of stromal cells in the tumour microenvironment , 2015, Nature Reviews Immunology.
[291] Andrew J. Ewald,et al. Matrix metalloproteinases and the regulation of tissue remodelling , 2007, Nature Reviews Molecular Cell Biology.
[292] J. Pouysségur,et al. Hypoxia signalling in cancer and approaches to enforce tumour regression , 2006, Nature.
[293] C. Koch,et al. Early detection of radiation therapy response in non‐Hodgkin's lymphoma xenografts by in vivo 1H magnetic resonance spectroscopy and imaging , 2010, NMR in biomedicine.
[294] Kirk C Hansen,et al. Collagen architecture in pregnancy-induced protection from breast cancer , 2013, Journal of Cell Science.
[295] Dania Daye,et al. Metabolic reprogramming in cancer: unraveling the role of glutamine in tumorigenesis. , 2012, Seminars in cell & developmental biology.
[296] V. Cuccurullo,et al. Biochemical and Pathophysiological Premises to Positron Emission Tomography With Choline Radiotracers , 2017, Journal of cellular physiology.
[297] A. Palucka,et al. Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet? , 2013, Science.
[298] Kevin W Eliceiri,et al. A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers , 2015, Oncotarget.
[299] Abdul Kader Sagar,et al. Second-harmonic generation imaging of cancer. , 2014, Methods in cell biology.
[300] J. Isaacs,et al. Rationale Behind Targeting Fibroblast Activation Protein–Expressing Carcinoma-Associated Fibroblasts as a Novel Chemotherapeutic Strategy , 2012, Molecular Cancer Therapeutics.
[301] Ruikang K. Wang,et al. Label-Free Optical Imaging of Lymphatic Vessels Within Tissue Beds IN VIVO , 2014, IEEE Journal of Selected Topics in Quantum Electronics.
[302] H. Moses,et al. Tumor-stroma interactions. , 2005, Current opinion in genetics & development.
[303] Michael Landthaler,et al. 2D luminescence imaging of pH in vivo , 2011, Proceedings of the National Academy of Sciences.
[304] Dehong Hu,et al. Smart hyaluronidase-actived theranostic micelles for dual-modal imaging guided photodynamic therapy. , 2016, Biomaterials.
[305] W. Marasco,et al. Safety and complications reporting on the re-implantation of culture-expanded mesenchymal stem cells using autologous platelet lysate technique. , 2010, Current stem cell research & therapy.
[306] Michael Lustig,et al. 3D compressed sensing for highly accelerated hyperpolarized 13C MRSI with in vivo applications to transgenic mouse models of cancer , 2010, Magnetic resonance in medicine.
[307] Fabian Kiessling,et al. Non-invasive imaging for studying anti-angiogenic therapy effects , 2013, Thrombosis and Haemostasis.
[308] D. Le Bihan,et al. Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. , 1988, Radiology.
[309] O. De Wever,et al. Fibroblast activation protein‐α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations , 2016, Molecular oncology.
[310] A. Gaumann,et al. Intravital microscopy of tumor angiogenesis and regression in the dorsal skin fold chamber: mechanistic insights and preclinical testing of therapeutic strategies , 2009, Clinical & Experimental Metastasis.
[311] M. Helguera,et al. Noninvasive Quantitative Imaging of Collagen Microstructure in Three-Dimensional Hydrogels Using High-Frequency Ultrasound. , 2015, Tissue engineering. Part C, Methods.
[312] Kyle M. Jones,et al. A comparison of iopromide and iopamidol, two acidoCEST MRI contrast media that measure tumor extracellular pH. , 2015, Contrast media & molecular imaging.
[313] Cristina Martelli,et al. In vivo imaging of immune cell trafficking in cancer , 2011, European Journal of Nuclear Medicine and Molecular Imaging.
[314] A. Pena,et al. Second harmonic imaging and scoring of collagen in fibrotic tissues. , 2007, Optics express.
[315] Hendrik Lehnert,et al. Interaction of tumor cells with the microenvironment , 2011, Cell Communication and Signaling.
[316] S. Javerzat,et al. FTIR spectro-imaging of collagen scaffold formation during glioma tumor development , 2013, Analytical and Bioanalytical Chemistry.
[317] Kristian Pietras,et al. Hallmarks of cancer: interactions with the tumor stroma. , 2010, Experimental cell research.
[318] Deepti S Vikram,et al. Methods for noninvasive imaging of tissue hypoxia. , 2007, Antioxidants & redox signaling.
[319] Man Chen,et al. Three‐Dimensional Contrast‐Enhanced Sonography in the Assessment of Breast Tumor Angiogenesis , 2014, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.
[320] Michal Neeman,et al. Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by magnetic resonance imaging. , 2005, Cancer research.
[321] H. Youn,et al. In Vivo Non Invasive Molecular Imaging for Immune Cell Tracking in Small Animals , 2012, Immune network.
[322] M. Simpson,et al. Emerging roles for hyaluronidase in cancer metastasis and therapy. , 2014, Advances in cancer research.
[323] Ellen Ackerstaff,et al. Choline phospholipid metabolism in cancer: consequences for molecular pharmaceutical interventions. , 2006, Molecular pharmaceutics.
[324] L. Álvarez-Vallina,et al. Tumor Immunotherapy Using Gene-Modified Human Mesenchymal Stem Cells Loaded into Synthetic Extracellular Matrix Scaffolds , 2009, Stem cells.
[325] M. Karin,et al. Immunity, Inflammation, and Cancer , 2010, Cell.
[326] B. Oliva,et al. In Vivo Tumor Targeting and Imaging with Engineered Trivalent Antibody Fragments Containing Collagen-Derived Sequences , 2009, PloS one.
[327] Hanry Yu,et al. Pulse-modulated second harmonic imaging microscope quantitatively demonstrates marked increase of collagen in tumor after chemotherapy. , 2010, Journal of biomedical optics.
[328] D L Buckley,et al. Tracer kinetic modelling in MRI: estimating perfusion and capillary permeability , 2012, Physics in medicine and biology.
[329] Michael Detmar,et al. In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography. , 2010, Cancer research.
[330] M. Neeman,et al. Molecular imaging of angiogenesis , 2007, Journal of magnetic resonance imaging : JMRI.
[331] Z. Werb,et al. Dynamic, long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy. , 2011, Cold Spring Harbor protocols.
[332] David M. Wilson,et al. The Potential of Metabolic Imaging. , 2016, Seminars in nuclear medicine.
[333] Gert-Jan Bakker,et al. Third harmonic generation microscopy of cells and tissue organization , 2016, Journal of Cell Science.
[334] Edward A. Randtke,et al. Multislice CEST MRI improves the spatial assessment of tumor pH , 2017, Magnetic resonance in medicine.
[335] Steven P Sourbron,et al. Classic models for dynamic contrast‐enhanced MRI , 2013, NMR in biomedicine.
[336] H. Choi,et al. Mesenchymal stem cell-based cell engineering with multifunctional mesoporous silica nanoparticles for tumor delivery. , 2013, Biomaterials.
[337] Kevin W. Eliceiri,et al. Automated quantification of aligned collagen for human breast carcinoma prognosis , 2014, Journal of pathology informatics.
[338] E. Puré,et al. Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells. , 2015, Cancer research.
[339] Pu Wang,et al. Mapping lipid and collagen by multispectral photoacoustic imaging of chemical bond vibration , 2012, Journal of biomedical optics.
[340] D. Kass,et al. In vitro system to study realistic pulsatile flow and stretch signaling in cultured vascular cells. , 2000, American journal of physiology. Cell physiology.
[341] C. Betsholtz,et al. Endothelial/Pericyte Interactions , 2005, Circulation research.
[342] V. Weaver,et al. The extracellular matrix modulates the hallmarks of cancer , 2014, EMBO reports.
[343] U. Haberkorn,et al. Molecular imaging of tumor metabolism and apoptosis. , 2007, Ernst Schering Foundation symposium proceedings.
[344] D. Engelman,et al. Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer , 2014, Proceedings of the National Academy of Sciences.
[345] Jae-Hyun Park,et al. Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. , 2012, Cancer cell.
[346] Stephanie Alexander,et al. Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model , 2008, Histochemistry and Cell Biology.
[347] F. Sotgia,et al. Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis. , 2012, Antioxidants & redox signaling.
[348] Kuiwon Choi,et al. Photo-crosslinked hyaluronic acid nanoparticles with improved stability for in vivo tumor-targeted drug delivery. , 2013, Biomaterials.
[349] T. Bugge,et al. Imaging collagen degradation in vivo highlights a key role for M2-polarized macrophages in extracellular matrix degradation , 2013, Oncoimmunology.
[350] D. Hirst,et al. Mesenchymal stem cells as a gene therapy carrier for treatment of fibrosarcoma. , 2009, Cytotherapy.
[351] Jeffrey W. Smith,et al. Right on TARGET: glutamine metabolism in cancer , 2015, Oncoscience.
[352] C. Müller-Tidow,et al. Multipotent mesenchymal stromal cells promote tumor growth in distinct colorectal cancer cells by a β1‐integrin‐dependent mechanism , 2016, International journal of cancer.
[353] Y. Woo,et al. Cancer-Associated Fibroblasts Promote Proliferation of Endometrial Cancer Cells , 2013, PloS one.
[354] Sarah J L Payne,et al. Influence of the tumor microenvironment on angiogenesis. , 2011, Future oncology.
[355] H. Shu,et al. Application of Metabolic PET Imaging in Radiation Oncology , 2012, Radiation research.
[356] J. Camps,et al. Quantitative measurement of fibrosis in pancreatic tissue. Evaluation of a colorimetric method. , 1991, International journal of pancreatology : official journal of the International Association of Pancreatology.