Direct Composition Analysis of a Dynamic Library of Imines in an Aqueous Medium

Dynamic Combinatorial Chemistry: Direct detection of imines in water and their adaptive re-equilibration in the presence of a target are possible by simple HPLC analysis. The equilibrating mixture is fixed by a fast drop in the pH during the analytical step. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)

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