A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1
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M. Tabaton | M. Guglielmotto | P. Gamba | G. Testa | S. Gargiulo | G. Leonarduzzi | S. Giannelli | E. Tamagno | Erica Staurenghi | Michela Guglielmotto
[1] Yuan Zhang,et al. The role of ubiquitin proteasomal system and autophagy-lysosome pathway in Alzheimer’s disease , 2017, Reviews in the neurosciences.
[2] Timothy A. Miller,et al. Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy , 2017, Science Translational Medicine.
[3] L. Iuliano,et al. Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation , 2016, Redox biology.
[4] M. Tabaton,et al. Beta‐amyloid 1‐42 monomers, but not oligomers, produce PHF‐like conformation of Tau protein , 2016, Aging cell.
[5] G. Poli,et al. Oxysterols and mechanisms of survival signaling. , 2016, Molecular aspects of medicine.
[6] G. Poli,et al. Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells. , 2016, Free radical biology & medicine.
[7] A. Romano,et al. The Role of Brain Cholesterol and its Oxidized Products in Alzheimer's Disease. , 2016, Current Alzheimer research.
[8] P. Dutar,et al. Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology. , 2015, Human molecular genetics.
[9] H. Braak,et al. The preclinical phase of the pathological process underlying sporadic Alzheimer's disease. , 2015, Brain : a journal of neurology.
[10] G. Poli,et al. Oxidized cholesterol as the driving force behind the development of Alzheimer’s disease , 2015, Front. Aging Neurosci..
[11] L. Iuliano,et al. Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation. , 2014, Free radical biology & medicine.
[12] T. Hankemeier,et al. Analysis of oxysterols and vitamin D metabolites in mouse brain and cell line samples by ultra-high-performance liquid chromatography-atmospheric pressure photoionization-mass spectrometry. , 2014, Journal of chromatography. A.
[13] A. Mauro,et al. Up-regulation of β-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine , 2014, Aging cell.
[14] Yoshiro Saito,et al. Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death☆ , 2013, Redox biology.
[15] Gabriel M. Belfort,et al. The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-d-Aspartate Receptors , 2013, The Journal of Neuroscience.
[16] Y. Urano,et al. Suppression of amyloid‐β production by 24S‐hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[17] O. Ghribi,et al. Gadd153 and NF-κB Crosstalk Regulates 27-Hydroxycholesterol-Induced Increase in BACE1 and β-Amyloid Production in Human Neuroblastoma SH-SY5Y Cells , 2013, PloS one.
[18] L. Guarente,et al. Sirtuin deacetylases in neurodegenerative diseases of aging , 2013, Cell Research.
[19] G. Poli,et al. Potentiation of amyloid-β peptide neurotoxicity in human dental-pulp neuron-like cells by the membrane lipid peroxidation product 4-hydroxynonenal. , 2012, Free radical biology & medicine.
[20] G. Donmez. The neurobiology of sirtuins and their role in neurodegeneration. , 2012, Trends in pharmacological sciences.
[21] O. Ghribi,et al. Silencing GADD153/CHOP Gene Expression Protects against Alzheimer's Disease-Like Pathology Induced by 27-Hydroxycholesterol in Rabbit Hippocampus , 2011, PloS one.
[22] T. Cotter,et al. Hydrogen peroxide: a Jekyll and Hyde signalling molecule , 2011, Cell Death and Disease.
[23] G. Poli,et al. Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions. , 2011, Free radical biology & medicine.
[24] J. Viña,et al. Interaction between 24‐hydroxycholesterol, oxidative stress, and amyloid‐β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime , 2011, Aging cell.
[25] T. Yamamori,et al. 24(S)-Hydroxycholesterol Induces Neuronal Cell Death through Necroptosis, a Form of Programmed Necrosis* , 2011, The Journal of Biological Chemistry.
[26] Hyoung-Gon Lee,et al. The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations , 2011, The Lancet Neurology.
[27] Chung-Soo Lee,et al. 7-Ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-κB and Akt pathways , 2011, Neurochemistry International.
[28] M. Mattson. Acetylation Unleashes Protein Demons of Dementia , 2010, Neuron.
[29] V. Haroutunian,et al. Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy , 2010, Neuron.
[30] E. Mandelkow,et al. Proteolytic processing of tau. , 2010, Biochemical Society transactions.
[31] G. Poli,et al. Pro-oxidant and proapoptotic effects of cholesterol oxidation products on human colonic epithelial cells: a potential mechanism of inflammatory bowel disease progression. , 2009, Free radical biology & medicine.
[32] Z. Arvanitakis,et al. Brain sterol dysregulation in sporadic AD and MCI: relationship to heme oxygenase‐1 , 2009, Journal of neurochemistry.
[33] Steve Meaney,et al. Oxysterols and neurodegenerative diseases. , 2009, Molecular aspects of medicine.
[34] C. Garenc,et al. Effect of 27-hydroxycholesterol on survival and death of human macrophages and vascular smooth muscle cells , 2009, Free radical research.
[35] D. Bennett,et al. Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease , 2009, Journal of neuropathology and experimental neurology.
[36] J. Frangos,et al. Effects of amyloid beta-peptides on the lysis tension of lipid bilayer vesicles containing oxysterols. , 2008, Biophysical journal.
[37] A. Nordberg,et al. Regulation of α- and β-secretase activity by oxysterols: Cerebrosterol stimulates processing of APP via the α-secretase pathway , 2007 .
[38] A. Berthier,et al. 7‐Ketocholesterol‐induced apoptosis , 2005, The FEBS journal.
[39] I. Grundke‐Iqbal,et al. Tau pathology in Alzheimer disease and other tauopathies. , 2005, Biochimica et biophysica acta.
[40] G. Johnson,et al. Tau phosphorylation in neuronal cell function and dysfunction , 2004, Journal of Cell Science.
[41] P. Davies,et al. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms , 2003, Journal of neurochemistry.
[42] I. Grundke‐Iqbal,et al. Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease , 2002, FEBS letters.
[43] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[44] Richard Hollister,et al. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease , 1997, Annals of neurology.
[45] O. Ghribi,et al. Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices. , 2010, Journal of Alzheimer's disease : JAD.
[46] F. LaFerla,et al. Alzheimer's disease. , 2010, The New England journal of medicine.
[47] A. Berthier,et al. Involvement of several pro-apoptotic but also anti-apoptotic calcium-dependent transduction pathways , 2005 .
[48] H. Braak,et al. Neuropathological stageing of Alzheimer-related changes , 2004, Acta Neuropathologica.
[49] Prasanthi,et al. Molecular Neurodegeneration Differential Effects of 24-hydroxycholesterol and 27-hydroxycholesterol on Β-amyloid Precursor Protein Levels and Processing in Human Neuroblastoma Sh-sy5y Cells , 2022 .