Fourteen Newly Recognized Proteins at the Human Neuromuscular Junctions‐and Their Nonjunctional Accumulation in Inclusion‐Body Myositisa a

[1]  Neil R. Cashman,et al.  Cellular isoform of the scrapie agent protein participates in lymphocyte activation , 1990, Cell.

[2]  S. Prusiner,et al.  Molecular biology of prion diseases , 1991, Science.

[3]  K. Weisgraber Apolipoprotein E: structure-function relationships. , 1994, Advances in protein chemistry.

[4]  J. Fallon,et al.  Building synapses: agrin and dystroglycan stick together , 1994, Trends in Neurosciences.

[5]  I. Weissman,et al.  Cell surface molecule associated with lymphocyte homing is a ubiquitinated branched-chain glycoprotein. , 1986, Science.

[6]  P. S. St George-Hyslop,et al.  Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. , 1987, Science.

[7]  D. Selkoe,et al.  Normal and abnormal biology of the beta-amyloid precursor protein. , 1994, Annual review of neuroscience.

[8]  W. Engel,et al.  De novo neuromuscular junction formation on human muscle fibres cultured in monolayer and innervated by foetal rat spinal cord: Ultrastructural and ultrastructural-cytochemical studies , 1987, Journal of neurocytology.

[9]  M. Sporn,et al.  Transforming growth factor-beta: biological function and chemical structure. , 1986, Science.

[10]  L. Hansen,et al.  Criteria for Alzheimer's Disease and the Nosology of Dementia with Lewy Bodies , 1997, Neurology.

[11]  J. Massagué,et al.  Transforming growth factor beta induces myoblast differentiation in the presence of mitogens. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[12]  P. S. St George-Hyslop,et al.  SOD1 missense mutation in an Italian family with ALS , 1994, Neurology.

[13]  H. Potter,et al.  α 1-Antichymotrypsin is associated solely with amyloid deposits containing the β-protein. Amyloid and cell localization of α 1-antichymotrypsin , 1990, Neurobiology of Aging.

[14]  K. Aldape,et al.  Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy , 1995, Cell.

[15]  H. Wiśniewski,et al.  Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[16]  W. Engel,et al.  Abnormal accumulation of prion protein mRNA in muscle fibers of patients with sporadic inclusion-body myositis and hereditary inclusion-body myopathy. , 1994, The American journal of pathology.

[17]  W. Engel,et al.  β‐Amyloid precursor epitopes in muscle fibers of inclusion body myositis , 1993 .

[18]  V. Fried,et al.  Ubiquitin has intrinsic proteolytic activity: implications for cellular regulation. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[19]  W. Engel,et al.  Strong immunoreactivity of β-amyloid precursor protein, including the β-amyloid protein sequence, at human neuromuscular junctions , 1992, Neuroscience Letters.

[20]  K. H. Lee,et al.  Nitric oxide as a messenger molecule for myoblast fusion. , 1994, The Journal of biological chemistry.

[21]  M. Smith,et al.  Retrograde signaling in the formation and maintenance of the neuromuscular junction. , 1994, Journal of neurobiology.

[22]  M. Villanova,et al.  Apolipoprotein E expression at neuromuscular junctions in mouse, rat and human skeletal muscle , 1994, FEBS letters.

[23]  J. Stamler,et al.  Nitric oxide in skeletal muscle , 1994, Nature.

[24]  K. Grzeschik,et al.  The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor , 1987, Nature.

[25]  A. Varshavsky,et al.  The ubiquitin system: functions and mechanisms , 1985 .

[26]  Ruedi Aebersold,et al.  A cellular gene encodes scrapie PrP 27-30 protein , 1985, Cell.

[27]  J. Massagué,et al.  Type beta transforming growth factor is an inhibitor of myogenic differentiation. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[28]  W. Engel,et al.  Immunocytochemical localization of ubiquitin at human neuromuscular junctions , 1992, Neuropathology and applied neurobiology.

[29]  The regulation of amyloid β protein precursor secretion and its modulatory role in cell adhesion , 1989, Neuron.

[30]  C. Nathan,et al.  Regulation of biosynthesis of nitric oxide. , 1994, The Journal of biological chemistry.

[31]  S. Muller,et al.  Presence of antibodies to ubiquitin during the autoimmune response associated with systemic lupus erythematosus. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[32]  Y. Courtois,et al.  Accumulation of NO synthase (type‐I) at the neuromuscular junctions in adult mice , 1996, Neuroreport.

[33]  W. Engel,et al.  Light and electron microscopic localization of beta-amyloid protein in muscle biopsies of patients with inclusion-body myositis. , 1992, The American journal of pathology.

[34]  E. Otomo,et al.  Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease , 1991, Brain Research.

[35]  W. Engel,et al.  Prion protein is abnormally accumulated in inclusion‐body myositis , 1993, Neuroreport.

[36]  B. Greenberg,et al.  A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors , 1988, Nature.

[37]  W. Engel,et al.  Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[38]  G. Robertson,et al.  Local Transcriptional Control of Utrophin Expression at the Neuromuscular Synapse* , 1997, The Journal of Biological Chemistry.

[39]  W. Engel,et al.  beta-Amyloid precursor protein mRNA is increased in inclusion-body myositis muscle. , 1993, Neuroreport.

[40]  W. Engel,et al.  Nitric oxide-induced oxidative stress in autosomal recessive and dominant inclusion-body myopathies. , 1998, Brain : a journal of neurology.

[41]  E. Shooter,et al.  Expression of apolipoprotein E during nerve degeneration and regeneration. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[42]  G. Multhaup,et al.  Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact. , 1988, The EMBO journal.

[43]  W. Engel,et al.  Alpha 1‐antichymotrypsin is strongly immunolocalized at normal human and rat neuromuscular junctions , 1994, Synapse.

[44]  B. Galer,et al.  Development and preliminary validation of a pain measure specific to neuropathic pain , 1997, Neurology.

[45]  S. Prusiner,et al.  The Neurochemistry of Prion Diseases , 1993, Journal of neurochemistry.

[46]  A. Ullrich,et al.  Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors , 1986, Nature.

[47]  W. Engel,et al.  New advances in the understanding of sporadic inclusion‐body myositis and hereditary inclusion‐body myopathies , 1995, Current opinion in rheumatology.

[48]  W. Engel,et al.  Immunolocalization of Nitric Oxide Synthases at the Postsynaptic Domain of Human and Rat Neuromuscular Junctions—Light and Electron Microscopic Studies , 1997, Experimental Neurology.

[49]  R. Mahley,et al.  Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. , 1988, Science.

[50]  D. Bolton,et al.  Purification and partial characterization of the normal cellular homologue of the scrapie agent protein. , 1988, The Journal of infectious diseases.

[51]  B. Festoff,et al.  Plasminogen activators and inhibitors: roles in muscle and neuromuscular regeneration. , 1987, Progress in brain research.

[52]  G. Cole,et al.  Amyloid β-protein precursor is associated with extracellular matrix , 1990, Brain Research.

[53]  B. Lu,et al.  Nitric oxide mediates activity-dependent synaptic suppression at developing neuromuscular synapses , 1995, Nature.

[54]  L. Villa-komaroff,et al.  Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease , 1988, Nature.

[55]  B. Anderton,et al.  Beta amyloid precursor protein mediates neuronal cell‐cell and cell‐surface adhesion , 1991, Journal of neuroscience research.

[56]  W. Engel,et al.  Prion protein is strongly immunolocalized at the postsynaptic domain of human normal neuromuscular junctions , 1993, Neuroscience Letters.

[57]  J. Fallon,et al.  The role of agrin in synapse formation. , 1995, Annual review of neuroscience.

[58]  A. Roses,et al.  Apolipoprotein E Is Localized to the Cytoplasm of Human Cortical Neurons: A Light and Electron Microscopic Study , 1994, Journal of neuropathology and experimental neurology.

[59]  D. Selkoe,et al.  Immunochemical identification of the serine protease inhibitor α 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease , 1988, Cell.

[60]  S. Prusiner,et al.  Antibodies to a scrapie prion protein , 1984, Nature.

[61]  R. Mayer,et al.  Ubiquitin, cell stress and diseases of the nervous system , 1990, Neuropathology and applied neurobiology.

[62]  M. Sporn,et al.  Transforming growth factor-beta: recent progress and new challenges , 1992, The Journal of cell biology.

[63]  W. Engel,et al.  βAPP gene transfer into cultured human muscle induces inclusion‐body myositis aspects , 1997 .

[64]  W. Engel,et al.  Apolipoprotein E immunoreactive deposits in inclusion-body muscle diseases , 1994, The Lancet.

[65]  T. Dawson,et al.  Gases as biological messengers: nitric oxide and carbon monoxide in the brain , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[66]  W. Engel,et al.  Immunocytochemical localization of desmin at human neuromuscular junctions , 1990, Neurology.

[67]  W. Engel,et al.  Human muscle cultured in monolayer and cocultured with fetal rat spinal cord: importance of dorsal root ganglia for achieving successful functional innervation , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[68]  C. S. Park,et al.  Constitutive expression and structural diversity of inducible isoform of nitric oxide synthase in human tissues. , 1996, Life sciences.

[69]  W. Engel,et al.  Immunolocalization of ubiquitin in muscle biopsies of patients with inclusion body myositis and oculopharyngeal muscular dystrophy , 1991, Neuroscience Letters.

[70]  J. Gallo,et al.  Ubiquitous variations in nerves , 1989, Nature.

[71]  Andreas Weidemann,et al.  Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein , 1989, Cell.

[72]  D. Selkoe,et al.  Twisted tubulofilaments of inclusion body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau. , 1994, The American journal of pathology.

[73]  W. Engel,et al.  Difference in Expression of Phosphorylated Tau Epitopes between Sporadic Inclusion‐body Myositis and Hereditary Inclusion‐body Myopathies , 1996, Journal of neuropathology and experimental neurology.

[74]  S. Zacks,et al.  THE FINE STRUCTURE OF THE MYASTHENIC NEUROMUSCULAR JUNCTION , 1962, Journal of Neuropathology and Experimental Neurology.

[75]  A. Goldberg,et al.  Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway. , 1996, The New England journal of medicine.

[76]  A. Ciechanover,et al.  The ubiquitin pathway for the degradation of intracellular proteins. , 1986, Progress in nucleic acid research and molecular biology.

[77]  K. Weisgraber,et al.  Apolipoprotein E and apolipoprotein E messenger RNA in muscle of inclusion body myositis and myopathies , 1996, Annals of neurology.

[78]  Y. Huang,et al.  Nitric oxide increases calcium/calmodulin-dependent phosphorylation of proteins in the postsynaptic density of adult rat cerebral cortex. , 1996, Brain research. Molecular brain research.

[79]  G. Hall,et al.  Axotomy-induced neurofilament phosphorylation is inhibited in situ by micromjection of PKA and PKC inhibitors into identified lamprey neurons , 1993, Neuron.

[80]  M. Nakane,et al.  Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. , 1994, Hypertension.

[81]  W. Engel,et al.  Increase of nitric oxide synthases and nitrotyrosine in inclusion‐body myositis , 1996, Neuroreport.

[82]  S. Prusiner,et al.  Human prion diseases , 1994, Annals of neurology.

[83]  J. Beckman,et al.  The role of peroxynitrite in nitric oxide-mediated toxicity. , 1995, Current topics in microbiology and immunology.

[84]  N. Katunuma,et al.  Abnormal expression of a serine protease in human dystrophic muscle. , 1978, Journal of biochemistry.

[85]  G. Glenner,et al.  Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein , 1984 .

[86]  D. Bredt,et al.  Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains , 1996, Cell.

[87]  Walter Schubert,et al.  Localization of Alzheimer βA4 amyloid precursor protein at central and peripheral synaptic sites , 1991, Brain Research.

[88]  G. Salvesen,et al.  Human plasma proteinase inhibitors. , 1983, Annual review of biochemistry.

[89]  S. Froehner,et al.  Dystrophin-associated proteins and synapse formation: Is α-dystroglycan the agrin receptor? , 1994, Cell.

[90]  S. Prusiner,et al.  Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene , 1986, Cell.