Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
暂无分享,去创建一个
B. Stockwell | Yanyan Cai | F. Zandkarimi | Deguang Liang | Zeda Zhang | Hua Wang | Xuejun Jiang | Yan Feng | Wei Gu | Jinnie Kim | Fereshteh Zandkarimi
[1] Xuejun Jiang,et al. H3K4me3 regulates RNA polymerase II promoter-proximal pause-release , 2023, Nature.
[2] J. Tobias,et al. Ferroptosis of tumour neutrophils causes immune suppression in cancer , 2022, Nature.
[3] B. Stockwell. Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications , 2022, Cell.
[4] T. Vanden Berghe,et al. Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity , 2022, Nature Communications.
[5] E. Leung,et al. In vitro breast cancer models for studying mechanisms of resistance to endocrine therapy , 2022, Exploration of targeted anti-tumor therapy.
[6] Xuejun Jiang,et al. Ferroptosis at the intersection of lipid metabolism and cellular signaling. , 2022, Molecular cell.
[7] V. O’Donnell. New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease , 2022, Biochemical Society transactions.
[8] W. Zou,et al. CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4. , 2022, Cancer cell.
[9] OUP accepted manuscript , 2022, Nucleic Acids Research.
[10] H. Shindou,et al. Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity , 2021, The Journal of biological chemistry.
[11] J. Dittmer. Nuclear Mechanisms Involved in Endocrine Resistance , 2021, Frontiers in Oncology.
[12] B. Stockwell,et al. iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4 , 2021, Nature Communications.
[13] Kellen L. Olszewski,et al. DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer , 2021, Nature.
[14] W. Figg,et al. Resistance to second-generation androgen receptor antagonists in prostate cancer , 2021, Nature Reviews Urology.
[15] Maojie Yang,et al. CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability. , 2021, Cell metabolism.
[16] B. Stockwell,et al. Ferroptosis: mechanisms, biology and role in disease , 2021, Nature Reviews Molecular Cell Biology.
[17] I. Bahar,et al. Phospholipase iPLA2β Averts Ferroptosis By Eliminating A Redox Lipid Death Signal , 2020, Nature Chemical Biology.
[18] C. Rudin,et al. Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer , 2020, Cell reports.
[19] C. Thompson,et al. Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis , 2020, Proceedings of the National Academy of Sciences.
[20] Callen T. Wallace,et al. PLA2G6 guards placental trophoblasts against ferroptotic injury , 2020, Proceedings of the National Academy of Sciences.
[21] Konnor C. La,et al. Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers , 2020, Nature Chemical Biology.
[22] Vianne R. Gao,et al. Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer , 2020, Cancer cell.
[23] D. Pe’er,et al. Regenerative potential of prostate luminal cells revealed by single-cell analysis , 2020, Science.
[24] Stephen A. Sastra,et al. Cysteine depletion induces pancreatic tumor ferroptosis in mice , 2020, Science.
[25] C. Arteaga,et al. Overcoming Endocrine Resistance in Breast Cancer. , 2020, Cancer cell.
[26] I. Bahar,et al. Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death , 2020, Nature Chemical Biology.
[27] B. Stockwell,et al. GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling , 2019, ACS central science.
[28] Edward W. Tate,et al. FSP1 is a glutathione-independent ferroptosis suppressor , 2019, Nature.
[29] J. Olzmann,et al. The CoQ oxidoreductase FSP1 acts in parallel to GPX4 to inhibit ferroptosis , 2019, Nature.
[30] B. Stockwell,et al. Intercellular interaction dictates cancer cell ferroptosis via Merlin-YAP signalling , 2019, Nature.
[31] P. Dobrzyn,et al. Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer , 2019, Cancers.
[32] D. Green. The Coming Decade of Cell Death Research: Five Riddles , 2019, Cell.
[33] B. Stockwell,et al. Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model. , 2019, Cell chemical biology.
[34] Shibing Deng,et al. Cystine–glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity , 2019, Proceedings of the National Academy of Sciences.
[35] A. Chinnaiyan,et al. CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy , 2019, Nature.
[36] J. Olzmann,et al. Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State. , 2019, Cell chemical biology.
[37] Asher Mullard. First targeted protein degrader hits the clinic , 2019, Nature Reviews Drug Discovery.
[38] Minghui Gao,et al. Role of Mitochondria in Ferroptosis. , 2019, Molecular cell.
[39] F. Torti,et al. Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death. , 2019, Cancer research.
[40] Kendall R. Sanson,et al. Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities , 2018, Nature Communications.
[41] Jason S. Lewis,et al. A PET Imaging Strategy for Interrogating Target Engagement and Oncogene Status in Pancreatic Cancer , 2018, Clinical Cancer Research.
[42] Wei Li,et al. BAP1 links metabolic regulation of ferroptosis to tumor suppression , 2018, Nature Cell Biology.
[43] David S. Wishart,et al. MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis , 2018, Nucleic Acids Res..
[44] Henry W. Long,et al. Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer , 2017, eLife.
[45] A. Walch,et al. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. , 2017, Nature chemical biology.
[46] Simon C Watkins,et al. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. , 2017, Nature chemical biology.
[47] I. Goldstein,et al. Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions , 2016, Cell.
[48] V. Arora,et al. Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer , 2015, Nature Reviews Cancer.
[49] G. Superti-Furga,et al. Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death , 2015, ACS chemical biology.
[50] W. Gu,et al. Ferroptosis as a p53-mediated activity during tumour suppression , 2015, Nature.
[51] Steven L Salzberg,et al. HISAT: a fast spliced aligner with low memory requirements , 2015, Nature Methods.
[52] Alexandro E. Trevino,et al. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex , 2014, Nature.
[53] Jun S. Liu,et al. MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens , 2014, Genome Biology.
[54] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[55] E. Cuppen,et al. Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures , 2014, Cell.
[56] Jindan Yu,et al. Cooperativity and Equilibrium with FOXA1 Define the Androgen Receptor Transcriptional Program , 2014, Nature Communications.
[57] Matthew E. Welsch,et al. Regulation of Ferroptotic Cancer Cell Death by GPX4 , 2014, Cell.
[58] Wei Shi,et al. featureCounts: an efficient general purpose program for assigning sequence reads to genomic features , 2013, Bioinform..
[59] Christof Fellmann,et al. An optimized microRNA backbone for effective single-copy RNAi. , 2013, Cell reports.
[60] D. Zheng,et al. Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade , 2013, Cell.
[61] D. Zheng,et al. ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss , 2013, Nature Medicine.
[62] J. Balsinde,et al. Phospholipid sources for adrenic acid mobilization in RAW 264.7 macrophages. Comparison with arachidonic acid. , 2012, Biochimica et biophysica acta.
[63] M. R. Lamprecht,et al. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death , 2012, Cell.
[64] H. Scher,et al. Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer , 2009, Science.
[65] R. Murphy,et al. Lysophospholipid Acyltransferases and Arachidonate Recycling in Human Neutrophils* , 2008, Journal of Biological Chemistry.
[66] Takao Shimizu,et al. Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity , 2008, Proceedings of the National Academy of Sciences.
[67] M. Gelb,et al. Cloning and recombinant expression of human group IIF-secreted phospholipase A(2). , 2000, Biochemical and biophysical research communications.
[68] R. Branch,et al. Estrogen and tamoxifen metabolites protect smooth muscle cell membrane phospholipids against peroxidation and inhibit cell growth. , 1999, Circulation research.