Antimykotisch wirksame Imidazolyl‐alkene: Synthese und Röntgenstrukturanalyse von Omoconazol

Antimycotic Imidazolyl-alkenes: Synthesis and X-Ray Crystal Structure of Omoconazol The synthesis of omoconazol 4 from 2′,4′-dichloro-α-(1H-imidazol-1-yl)propiophenon (5) and 1-bromo-2-(4-chlorophenoxy)ethane (6) is described. Omoconazol, C20H17Cl3N2O2, crystallises in the monoclinic space group P21/n, a = 14.329, b = 8.703, c = 16.791 A, β = 105.75°. The crystal structure showed that omoconazol has the (Z)-configuration, in accordance with previous NMR results.