Marie-Jean-Pierre Flourens (1794–1867) and Cortical Localization

The child prodigy Marie-Jean-Pierre Flourens received his medical degree at Montpellier when aged 19. As a young promising physician Flourens was asked to investigate Gall’s controversial views on cerebral localization. To test Gall’s assertions, Flourens developed ablation as a procedure to explore the workings of the brain. By removing anatomically defined areas of the brain of an animal and watching its behaviour, he thought he might localize certain functions. Flourens did not favour the idea of cerebral localization and concluded that the brain functioned as a whole and thus arose the concept of ‘cerebral equipotentiality’. This culminated in his 1824 Recherches expérimentales sur les propriétés et les fonctions du système nerveux. His techniques were, however, crude and imperfect, and his experiments were mainly on birds. Much criticism and debate ensued. A gifted man, Flourens also advanced the physiology of the vestibular apparatus and described the anaesthetic properties of ether.

[1]  J. Pearce.  Brodmann’s cortical maps , 2005, Journal of Neurology, Neurosurgery & Psychiatry.

[2]  K. Lashley.  The problem of serial order in behavior , 1951 .

[3]  F. Schiller,et al.  Paul Broca: Founder of French Anthropology, Explorer of the Brain , 1992 .

[4]  C. Goetz,et al.  Battle of the titans , 2000, Neurology.

[5]  J. Pearce.  Sir David Ferrier MD, FRS , 2003, Journal of neurology, neurosurgery, and psychiatry.

[6]  E. Clarke,et al.  An illustrated history of brain function : imaging the brain from antiquity to the present , 1996 .

[7]  K. Brodmann.  Vergleichende Lokalisationslehre der Großhirnrinde : in ihren Prinzipien dargestellt auf Grund des Zellenbaues , 1985 .

[8]  J. Bouillaud.  Recherches cliniques propres à démontrer que la perte de la parole correspond à la lésion des lobules antérieures du cerveau, et à confirmer l’opinion de M. Gall sur le siège de l’organe du language articulé , 1825 .

[9]  L. Garey.  Brodmann's localisation in the cerebral cortex , 1999 .

[10]  P. Flourens.  Recherches expérimentales sur les propriétés et les fonctions du système nerveux dans les animaux vertébrés , 1842 .

[11]  F. Freemon.  Paul Broca: Founder of French Anthropology, Explorer of the Brain , 1993 .

[12]  E. Boring.  A History of Experimental Psychology. , 1930 .

[13]  D. Ferrier.  The Functions of the Brain , 1887, Edinburgh Medical Journal.

[14]  D. Ferrier,et al.  Experimental Researches in Cerebral Physiology and Pathology , 1873, Journal of anatomy and physiology.

[15]  E. S. Robinson.  A History of Experimental Psychology , 1930 .