Effect of At-Home Bleaching on Oxygen Saturation Levels in the Dental Pulp of Maxillary Central Incisors.

The present study assessed oxygen saturation (SaO2) levels before, during, and after at-home bleaching treatment in the pulps of healthy maxillary central incisors. SaO2 levels were measured in 136 healthy maxillary central incisors using a pulse oximeter. The bleaching protocol consisted of 10% carbamide peroxide gel placed in individual trays and used for four hours daily for 14 days. SaO2 levels were assessed before bleaching (T0), immediately after the first session (T1), on the 7th day of treatment (T2), on the 15th day (the day following the last session) (T3), and 30 days after completion of the bleaching protocol (T4). Data were statistically analyzed using generalized estimating equations (GEE), Student's t test (p<0.05) and Pearson's correlation. Mean pulp SaO2 levels were 85.1% at T0, 84.9% at T1, 84.7% at T2, 84.3% at T3, and 85.0% at T4. Gradual reductions in SaO2 levels were observed, with significant differences (p<0.001) during the course of home bleaching treatment. However, 30 days after the end of the bleaching protocol, SaO2 levels returned to baseline levels. Home bleaching caused a reversible transient decrease in SaO2 levels in the pulps.

[1]  Cyntia R A Estrela,et al.  Oxygen Saturation in the Dental Pulp of Maxillary and Mandibular Molars - Part 2. , 2017, Brazilian dental journal.

[2]  Cyntia R A Estrela,et al.  Oxygen Saturation in the Dental Pulp of Maxillary Premolars in Different Age Groups - Part 1. , 2017, Brazilian Dental Journal.

[3]  Q. Zheng,et al.  Self‐repaired Process of a Traumatized Maxillary Central Incisor with Pulp Infarct after Horizontal Root Fracture Monitored by Laser Doppler Flowmetry Combined with Tissue Oxygen Monitor , 2017, Journal of endodontics.

[4]  G. Gavini,et al.  Pulse oximetry: a useful test for evaluating pulp vitality in traumatized teeth. , 2016, Dental Traumatology.

[5]  F. Setzer,et al.  Late Effects of Head and Neck Radiotherapy on Pulp Vitality Assessed by Pulse Oximetry. , 2016, Journal of endodontics.

[6]  K. Kilaru,et al.  An in vivo evaluation of the change in the pulpal oxygen saturation after administration of preoperative anxiolytics and local anesthesia , 2016, Journal of dental research, dental clinics, dental prospects.

[7]  Mehdi Ahmadi,et al.  The use of pulse oximetry in evaluation of pulp vitality in immature permanent teeth. , 2016, Dental traumatology : official publication of International Association for Dental Traumatology.

[8]  C. Estrela,et al.  Oxygen Saturation in Dental Pulp of Permanent Teeth: Difference between Children/Adolescents and Adults. , 2015, Journal of endodontics.

[9]  P. Martins-Filho,et al.  Effect of preventive use of nonsteroidal anti-inflammatory drugs on sensitivity after dental bleaching: a systematic review and meta-analysis. , 2015, Journal of the American Dental Association.

[10]  C. Estrela,et al.  Assessment of oxygen saturation in dental pulp of permanent teeth with periodontal disease. , 2014, Journal of endodontics.

[11]  C. Estrela,et al.  Oxygen saturation in the dental pulp of permanent teeth: a critical review. , 2014, Journal of endodontics.

[12]  M. L. Ratón,et al.  Randomized clinical trial on the efficacy and safety of four professional at-home tooth whitening gels. , 2014 .

[13]  H. Jafarzadeh,et al.  Comparison of the efficacy of a custom-made pulse oximeter probe with digital electric pulp tester, cold spray, and rubber cup for assessing pulp vitality. , 2012, Journal of endodontics.

[14]  F. Setzer,et al.  Clinical diagnosis of pulp inflammation based on pulp oxygenation rates measured by pulse oximetry. , 2012, Journal of endodontics.

[15]  Paulo Henrique dos Santos,et al.  Clinical evaluation of the effectiveness of different bleaching therapies in vital teeth , 2012, BDJ.

[16]  R. Basting,et al.  Clinical comparative study of the effectiveness of and tooth sensitivity to 10% and 20% carbamide peroxide home-use and 35% and 38% hydrogen peroxide in-office bleaching materials containing desensitizing agents. , 2012, Operative dentistry.

[17]  L. Baratieri,et al.  Clinical effectiveness and tooth sensitivity associated with different bleaching times for a 10 percent carbamide peroxide gel. , 2010, Journal of the American Dental Association.

[18]  J. Hebling,et al.  Human pulp responses to in-office tooth bleaching. , 2010, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[19]  R. I. Ferreira,et al.  Mesiodistal width and proximal enamel thickness of maxillary first bicuspids. , 2010, Brazilian oral research.

[20]  J. Hebling,et al.  Trans-enamel and trans-dentinal cytotoxic effects of a 35% H2O2 bleaching gel on cultured odontoblast cell lines after consecutive applications. , 2009, International endodontic journal.

[21]  G. Gavini,et al.  Determination of pulp vitality in vivo with pulse oximetry. , 2008, International endodontic journal.

[22]  Velayutham Gopikrishna,et al.  Comparison of electrical, thermal, and pulse oximetry methods for assessing pulp vitality in recently traumatized teeth. , 2007, Journal of endodontics.

[23]  A. Moule,et al.  The endodontic management of traumatized permanent anterior teeth: a review. , 2007, Australian dental journal.

[24]  I. Mjör,et al.  Pulp reaction to vital bleaching. , 2004, Operative dentistry.

[25]  Amitha M Hegde,et al.  Pulse oximetry: a diagnostic instrument in pulpal vitality testing. , 2002, The Journal of clinical pediatric dentistry.

[26]  R. Emling,et al.  Sensory response to thermal stimulation in human teeth. , 1980, Journal of endodontics.