Irido-lenticular abscess as the initial sign of Candida albicans endogenous endophthalmitis.

A-33-year-old man presented with 9 days of conjunctival erythema, pain, and worsening vision in the left eye. Anterior segment examination was significant for a well-defined, cream-colored iridociliary mass. Ultrasound biomicroscopy demonstrated an iris lesion with ciliary body and lenticular involvement. The authors performed a pars plana vitrectomy and lensectomy with an iris biopsy. Culture of the vitreous cassette and iris mass yielded a diagnosis of Candida albicans endophthalmitis. Clinicians encountering an iris nodule with lenticular involvement, even in an immunocompetent adult, are urged to consider a diagnosis of an endogenous endophthalmitis secondary to C. albicans.

[1]  K. Pelz,et al.  Endogenous endophthalmitis: microorganisms, disposition and prognosis. , 2007, Acta ophthalmologica Scandinavica.

[2]  U. Stenevi,et al.  Endophthalmitis after cataract surgery: a nationwide prospective study evaluating incidence in relation to incision type and location. , 2007, Ophthalmology.

[3]  H. Flynn,et al.  Culture-proven endogenous endophthalmitis: clinical features and visual acuity outcomes. , 2004, American journal of ophthalmology.

[4]  W. Powderly,et al.  A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients. , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[5]  P. Kaiser,et al.  Endogenous Endophthalmitis: An 18-Year Review of Culture-Positive Cases at a Tertiary Care Center , 2003, Medicine.

[6]  J. Rosenbaum,et al.  Iris nodules associated with infectious uveitis , 2002, The British journal of ophthalmology.

[7]  N. Rao,et al.  Endogenous mycotic endophthalmitis: variations in clinical and histopathologic changes in candidiasis compared with aspergillosis. , 2001, American journal of ophthalmology.

[8]  J. Vander,et al.  Intralenticular Candida species abscess in a premature infant. , 2000, American journal of ophthalmology.

[9]  P. A. Thomas,et al.  Keratomycotic malignant glaucoma. , 1991, Indian journal of ophthalmology.

[10]  J. Duker,et al.  Infantile endogenous Candida endophthalmitis presenting as a cataract. , 1989, Survey of ophthalmology.

[11]  B. Jones,et al.  Principles in the management of oculomycosis. XXXI Edward Jackson memorial lecture. , 1975, American journal of ophthalmology.

[12]  R. Monshizadeh,et al.  Isolated anterior uveitis as the initial sign of systemic candidemia. , 2003, Archives of ophthalmology.