Improved surgical margin definition by narrow band imaging for resection of oral squamous cell carcinoma: A prospective gene expression profiling study

Incomplete primary tumor excision contributes to localized postsurgical recurrence of oral squamous cell carcinoma (OSCC). The purpose of this study was to provide molecular evidence that surgical margin definition using narrow band imaging (NBI) resulted in more complete OSCC excision than conventional white light (WL) panendoscopy.

[1]  K. Lê Cao,et al.  A retrospective analysis of clinical features of oral malignant and potentially malignant disorders with and without oral epithelial dysplasia. , 2013, Oral surgery, oral medicine, oral pathology and oral radiology.

[2]  S. Warnakulasuriya Global epidemiology of oral and oropharyngeal cancer. , 2009, Oral oncology.

[3]  H. Kurita,et al.  Impact of different surgical margin conditions on local recurrence of oral squamous cell carcinoma. , 2010, Oral oncology.

[4]  High specificity of combined narrow band imaging and autofluorescence mucosal assessment of patients with head and neck cancer , 2013, Head & neck.

[5]  Crispin J. Miller,et al.  Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis , 2005, Bioinform..

[6]  A. Karabulut,et al.  Observer variability in the histologic assessment of oral premalignant lesions. , 1995, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[7]  Maryam Jessri,et al.  Next generation sequencing and its application in deciphering head and neck cancer. , 2014, Oral oncology.

[8]  D. Botstein,et al.  Cluster analysis and display of genome-wide expression patterns. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[9]  Gordon K Smyth,et al.  Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2004, Statistical applications in genetics and molecular biology.

[10]  M. Varvares,et al.  Surgical margin determination in head and neck oncology: Current clinical practice. The results of an International American Head and Neck Society Member Survey , 2005, Head & neck.

[11]  Chris T. A. Evelo,et al.  User-friendly solutions for microarray quality control and pre-processing on ArrayAnalysis.org , 2013, Nucleic Acids Res..

[12]  R. González-García,et al.  Local recurrences and second primary tumors from squamous cell carcinoma of the oral cavity: A retrospective analytic study of 500 patients , 2009, Head & neck.

[13]  Michael L. Hinni,et al.  Surgical margins in head and neck cancer: A contemporary review , 2013, Head & neck.

[14]  G. Bradley,et al.  Observer agreement in the grading of oral epithelial dysplasia. , 2003, Community dentistry and oral epidemiology.

[15]  C. Farah,et al.  Efficacy of narrow band imaging for detection and surveillance of potentially malignant and malignant lesions in the oral cavity and oropharynx: a systematic review. , 2014, Oral oncology.

[16]  Camile S. Farah,et al.  Advances in Optical Adjunctive Aids for Visualisation and Detection of Oral Malignant and Potentially Malignant Lesions , 2013, International journal of dentistry.

[17]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[18]  J. Reibel,et al.  Subjectivity in evaluating oral epithelial dysplasia, carcinoma in situ and initial carcinoma. , 1985, Journal of oral pathology.

[19]  H Lumerman,et al.  Oral epithelial dysplasia and the development of invasive squamous cell carcinoma. , 1995, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[20]  Robert Gentleman,et al.  Using GOstats to test gene lists for GO term association , 2007, Bioinform..

[21]  A. Ochiai,et al.  Microvascular irregularities are associated with composition of squamous epithelial lesions and correlate with subepithelial invasion of superficial‐type pharyngeal squamous cell carcinoma , 2010, Histopathology.

[22]  R. Nason,et al.  The clinical significance of the positive surgical margin in oral cancer. , 2007, Oral oncology.

[23]  I. Asahina,et al.  Clinicopathological risk factors for local recurrence in oral squamous cell carcinoma. , 2012, International journal of oral and maxillofacial surgery.

[24]  I. Kato,et al.  Simultaneous detection and typing of genital human papillomavirus DNA using the polymerase chain reaction. , 1991, The Journal of general virology.

[25]  Ignacio González,et al.  integrOmics: an R package to unravel relationships between two omics datasets , 2009, Bioinform..

[26]  E. Eisenberg,et al.  Intraexaminer and interexaminer reliability in the diagnosis of oral epithelial dysplasia. , 1995, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[27]  M. Lingen,et al.  Genetics/epigenetics of oral premalignancy: current status and future research. , 2011, Oral diseases.

[28]  Zhijin Wu,et al.  Preprocessing of oligonucleotide array data , 2004, Nature Biotechnology.