Mueller matrix decomposition of diffuse reflectance imaging in skeletal muscle.

Propagation of polarized light in skeletal muscle is significantly affected by anisotropic muscle structures. To completely characterize muscle polarization properties, we acquired the whole Mueller matrix images of the diffuse reflectance. A polar decomposition algorithm was applied to extract the individual diattenuation, retardance, and depolarization images from the measured Mueller matrix. The decomposed polarization properties in muscle show distinctly different patterns from those obtained in isotropic scattering media. Stretching the prerigor muscle sample induced clear changes in the raw polarization reflectance images. However, muscle stretching induced minimal changes in the decomposed Mueller matrix images.

[1]  G. Yao,et al.  Two-dimensional depth-resolved Mueller matrix characterization of biological tissue by optical coherence tomography. , 1999, Optics letters.

[2]  Gang Yao,et al.  Polarization-sensitive reflectance imaging in skeletal muscle. , 2008, Optics express.

[3]  S G Demos,et al.  Advances in Optical Imaging of Biomedical Media a , 1997, Annals of the New York Academy of Sciences.

[4]  Diana M. Hayes Error propagation in decomposition of Mueller matrices , 1997, Optics & Photonics.

[5]  A. de Martino,et al.  Forward and reverse product decompositions of depolarizing Mueller matrices. , 2007, Optics letters.

[6]  Gang Yao,et al.  Imaging 2D optical diffuse reflectance in skeletal muscle. , 2007, Optics express.

[7]  Michael S. Feld,et al.  Polarized light scattering spectroscopy for quantitative measurement of epithelial cellular structures in situ , 1999 .

[8]  Matthew H. Smith,et al.  Interpreting Mueller matrix images of tissues , 2001, SPIE BiOS.

[9]  Yanfang Li,et al.  Polarization-based optical imaging and processing techniques with application to the cancer diagnostics , 2002, SPIE BiOS.

[10]  S. Jacques,et al.  Imaging Superficial Tissues With Polarized Light , 2000 .

[11]  M. K. Swami,et al.  Polar decomposition of 3 x 3 Mueller matrix: a tool for quantitative tissue polarimetry. , 2006, Optics express.

[12]  Asima Pradhan,et al.  Discrimination of normal and dysplasia in cervix tissue by Mueller matrix analysis , 2008, SPIE BiOS.

[13]  J P Freyer,et al.  Polarized angular dependent spectroscopy of epithelial cells and epithelial cell nuclei to determine the size scale of scattering structures. , 2002, Journal of biomedical optics.

[14]  Zhongping Chen,et al.  Use of polar decomposition for the diagnosis of oral precancer. , 2007, Applied optics.

[15]  D. Huffman,et al.  Application of polarization effects in light scattering: a new biophysical tool. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[16]  R. Chipman,et al.  Interpretation of Mueller matrices based on polar decomposition , 1996 .

[17]  A Hielscher,et al.  Diffuse backscattering Mueller matricesof highly scattering media. , 1997, Optics express.

[18]  Gang Yao,et al.  Monitoring sarcomere structure changes in whole muscle using diffuse light reflectance. , 2006, Journal of biomedical optics.

[19]  M. K. Swami,et al.  Mueller matrix approach for determination of optical rotation in chiral turbid media in backscattering geometry. , 2006, Optics express.

[20]  Jérôme Morio,et al.  Influence of the order of diattenuator, retarder, and polarizer in polar decomposition of Mueller matrices. , 2004, Optics letters.

[21]  Stephen A. Boppart,et al.  In vivo detection of exercised-induced ultrastructural changes in genetically-altered murine skeletal muscle using polarization-sensitive optical coherence tomography. , 2006, Optics express.

[22]  Nirmalya Ghosh,et al.  Mueller matrix decomposition for extraction of individual polarization parameters from complex turbid media exhibiting multiple scattering, optical activity, and linear birefringence. , 2008, Journal of biomedical optics.