Macrocytosis and dysplastic anemia is associated with the cyclin-dependent kinase 4/6 inhibitor palbociclib in metastatic breast cancer

Palbociclib is a cyclin-dependent kinase (CDK) inhibitor of CDK4 and CDK6 that has been approved by the US Food and Drug Administration (FDA) for the treatment of estrogen receptor (ER)-positive, HER2-negative metastatic breast cancer (MBC), demonstrating an improvement in progression-free survival

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