Determination of Roxarsone Using Carbon Paste and Amberlite LA2 Modified Carbon Paste Electrodes

The methods for determination of the growth promoter 4-hydroxy-3-nitrobenzenearsonic acid (Roxarsone) in veterinary product and in poultry drinks have been developed using differential pulse voltammetry with carbon paste and Amberlite LA2 chemically modified carbon paste electrodes. Optimal conditions have been found for Roxarsone determination with nonmodified carbon paste electrodes with limit of determination being 3 µmol L–1. The sensitivity of the determination was further improved through Amberlite LA2 modification of the carbon paste with limit of determination being 0.1 µmol L–1. Modification also enabled preliminary accumulation of Roxarsone with the exchange of the supporting electrolyte.

[1]  P. Ugo,et al.  Ion-exchange voltammetry at polymer-coated electrodes: Principles and analytical prospects , 1995 .

[2]  Xiaohua Cai,et al.  Voltammetric determination of trace amounts of mercury with a carbon paste electrode modified with an anion-exchanger , 1993 .

[3]  K. Kalcher Chemically modified carbon paste electrodes in voltammetric analysis , 1990 .

[4]  W. Cullen,et al.  Liquid chromatography and mass spectrometry for the speciation of arsenic animal feed additives. , 1997, Journal of chromatography. A.

[5]  N. F. Morehouse,et al.  The effect of some aryl arsonic acids on experimental coccidiosis infection in chickens. , 1946, The Journal of parasitology.

[6]  P. Tuzhi,et al.  Selective extraction and voltammetric determination of gold at a chemically modified carbon paste electrode , 1993 .

[7]  K. Irgolic,et al.  Polarographic Reduction of Aromatic Arsonic and Arsinic Acids , 1977 .

[8]  D. Baker,et al.  Toxic effects of supplemental copper and roxarsone when fed alone or in combination to young pigs. , 1986, Journal of animal science.

[9]  C. C. Calvert Arsenicals in Animal Feeds and Wastes , 1975 .

[10]  W. Geiger,et al.  Voltammetric determination of agriculturally-significant benzenearsonic acids , 1981 .

[11]  J. Delplancke,et al.  Surfactant modified carbon paste electrode: part 1: electrochemical and microscopic characterization , 1994 .

[12]  Xiaohua Cai,et al.  Voltammetric behaviour of thallium(III) on carbon paste electrodes chemically modified with an anion exchanger , 1993 .

[13]  S. Pergantis,et al.  Speciation of arsenic animal feed additives by microbore high-performance liquid chromatography with inductively coupled plasma mass spectrometry. , 1997, The Analyst.

[14]  K. H. Mancy,et al.  Differential pulse polarography of phenylarsine oxide , 1978 .

[15]  M. Sevilla,et al.  Cathodic stripping voltammetry of paraquat on a carbon paste electrode modified with amberlite XAD-2 resin , 1992 .

[16]  R. Massey,et al.  Determination of the growth promoter, 4-hydroxy-3-nitrophenyl-arsonic acid in chicken tissue by coupled high-performance liquid chromatography–inductively coupled plasma mass spectrometry , 1994 .

[17]  S. Pergantis,et al.  Microscale Flow Injection and Microbore High-Performance Liquid Chromatography Coupled with Inductively Coupled Plasma Mass Spectrometry via a High-Efficiency Nebulizer , 1995 .

[18]  Jean-Michel Kauffmann,et al.  Sensors based on carbon paste in electrochemical analysis: A review with particular emphasis on the period 1990–1993 , 1995 .

[19]  S. Pergantis,et al.  Determination of Ten Organoarsenic Compounds Using Microbore High-performance Liquid Chromatography Coupled With Electrospray Mass Spectrometry–Mass Spectrometry , 1997 .