A census of amplified and overexpressed human cancer genes

[1]  Zoltan Dezso,et al.  Genome-wide functional synergy between amplified and mutated genes in human breast cancer. , 2008, Cancer research.

[2]  O. Delattre,et al.  Characterization of amplicons in neuroblastoma: High‐resolution mapping using DNA microarrays, relationship with outcome, and identification of overexpressed genes , 2008, Genes, chromosomes & cancer.

[3]  L. Trusolino,et al.  Drug development of MET inhibitors: targeting oncogene addiction and expedience , 2008, Nature Reviews Drug Discovery.

[4]  Antony V. Cox,et al.  Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing , 2008, Nature Genetics.

[5]  Andrew Menzies,et al.  Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution. , 2007, Genome research.

[6]  M. Ohira,et al.  Relationship of DDX1 and NAG gene amplification/overexpression to the prognosis of patients with MYCN-amplified neuroblastoma , 2007, Journal of Cancer Research and Clinical Oncology.

[7]  Kathy Pritchard-Jones,et al.  Amplification and Overexpression of CACNA1E Correlates with Relapse in Favorable Histology Wilms' Tumors , 2006, Clinical Cancer Research.

[8]  Alan Mackay,et al.  FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas , 2006, Clinical Cancer Research.

[9]  D. Albertson,et al.  Gene amplification in cancer. , 2006, Trends in genetics : TIG.

[10]  J. Pollack,et al.  RNA interference‐based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes , 2006, Genes, chromosomes & cancer.

[11]  M. Wigler,et al.  Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach , 2006, Cell.

[12]  S. Knuutila,et al.  Manifestation, mechanisms and mysteries of gene amplifications. , 2006, Cancer letters.

[13]  R. Huddart,et al.  Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults. , 2005, Cancer research.

[14]  I. Ellis,et al.  A 1 Mb minimal amplicon at 8p11–12 in breast cancer identifies new candidate oncogenes , 2005, Oncogene.

[15]  C. Vogel,et al.  Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with trastuzumab. , 2005, Clinical breast cancer.

[16]  F. Speleman,et al.  No evidence for correlation of DDX1 gene amplification with improved survival probability in patients with MYCN-amplified neuroblastomas. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[17]  G. Sauter,et al.  E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer , 2004, Oncogene.

[18]  H. Christiansen,et al.  Coamplification of DDX1 correlates with an improved survival probability in children with MYCN-amplified human neuroblastoma. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[19]  T. Hubbard,et al.  A census of human cancer genes , 2004, Nature Reviews Cancer.

[20]  R. Wooster,et al.  Amplification and overexpression of E2F3 in human bladder cancer , 2004, Oncogene.

[21]  Donna Albertson,et al.  Genomic and Expression Analysis of the 8p11–12 Amplicon in Human Breast Cancer Cell Lines , 2004, Cancer Research.

[22]  Robert L. Sutherland,et al.  Cyclin D1, EMS1 and 11q13 Amplification in Breast Cancer , 2003, Breast Cancer Research and Treatment.

[23]  J. Veltman,et al.  12p-Amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH , 2003, Oncogene.

[24]  N. Hayward Genetics of melanoma predisposition , 2003, Oncogene.

[25]  R. Huddart,et al.  Expression profile of genes from 12p in testicular germ cell tumors of adolescents and adults associated with i(12p) and amplification at 12p11.2–p12.1 , 2003, Oncogene.

[26]  R. Kucherlapati,et al.  Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes. , 2002, Cancer research.

[27]  Lyndsay N Harris,et al.  Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[28]  M. Schwab,et al.  Amplification of oncogenes revisited: from expression profiling to clinical application. , 2001, Cancer letters.

[29]  M. Schwab Oncogene amplification in solid tumors. , 1999, Seminars in cancer biology.

[30]  John N. Anderson,et al.  Novel formation and amplification of the PAX7-FKHR fusion gene in a case of alveolar rhabdomyosarcoma. , 1996, Genes, chromosomes & cancer.

[31]  A. Levine,et al.  Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. , 1994, Cancer research.

[32]  C. James,et al.  Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. , 1990, Proceedings of the National Academy of Sciences of the United States of America.