Breast cancer detection using MRF-based probable texture feature and decision-level fusion-based classification using HMM on thermography images

Breast cancer is one of the major causes of death for women in the last decade. Thermography is a breast imaging technique that can detect cancerous masses much faster than the conventional mammography technology. In this paper, a breast cancer detection algorithm based on asymmetric analysis as primitive decision and decision-level fusion by using Hidden Markov Model (HMM) is proposed. In this decision structure, by using primitive decisions obtained from extracted features from left and right breasts and also asymmetric analysis, final decision is determined by a new application of HMM. For this purpose, a novel texture feature based on Markov Random Field (MRF) model that is named MRF-based probable texture feature and another texture feature based on a new scheme in Local Binary Pattern (LBP) of the images are extracted. In the MRF-based probable texture feature, we try to capture breast texture information by using proper definition of neighborhood system and clique and also determination of new potential functions. Ultimately, our proposed breast cancer detection algorithm is evaluated on a variety dataset of thermography images and false negative rate of 8.3% and false positive rate of 5% are obtained on test image dataset. We propose a two-stage breast cancer detection algorithm by decision-level fusion.We tried to improve false accept of previous algorithms by our proposed algorithm.We used Hidden Markov Model as a fusion algorithm to fuse primitive decisions.We propose a novel texture feature based on Markov Random Field model.To extract color and edge information of images, we modified Local Binary Pattern.

[1]  Jun Zhou,et al.  Object Classification via Feature Fusion Based Marginalized Kernels , 2015, IEEE Geoscience and Remote Sensing Letters.

[2]  Xuelong Li,et al.  Optimized graph-based segmentation for ultrasound images , 2014, Neurocomputing.

[3]  Javad Haddadnia,et al.  Diagnosing Breast Cancer with the Aid of Fuzzy Logic Based on Data Mining of a Genetic Algorithm in Infrared Images , 2012 .

[4]  Edwin R. Hancock,et al.  Graph characteristics from the heat kernel trace , 2009, Pattern Recognit..

[5]  Hossein Pourghassem,et al.  Facial Expression Recognition Using ALGBP-TOP , 2013 .

[6]  Hossein Pourghassem,et al.  Breast cancer detection using spectral probable feature on thermography images , 2013, 2013 8th Iranian Conference on Machine Vision and Image Processing (MVIP).

[7]  Caro Lucas,et al.  Analysis of Breast Thermography Using Fractal Dimension to Establish Possible Difference between Malignant and Benign Patterns , 2010 .

[8]  Hossein Pourghassem,et al.  Medical X-ray Image Hierarchical Classification Using a Merging and Splitting Scheme in Feature Space , 2013, Journal of medical signals and sensors.

[9]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.

[10]  C. A. Lipari,et al.  The important role of infrared imaging in breast cancer , 2000, IEEE Engineering in Medicine and Biology Magazine.

[11]  D. Kennedy,et al.  A Comparative Review of Thermography as a Breast Cancer Screening Technique , 2009, Integrative cancer therapies.

[12]  Hossein Pourghassem,et al.  Content-based medical image classification using a new hierarchical merging scheme , 2008, Comput. Medical Imaging Graph..

[13]  H. Pourghassem,et al.  Mental Task Classification Based on HMM and BPNN , 2013, 2013 International Conference on Communication Systems and Network Technologies.

[14]  Hui Li,et al.  A New Infrared Thermal Imaging and Its Preliminary Investigation of Breast Disease Assessment , 2007, 2007 IEEE/ICME International Conference on Complex Medical Engineering.

[15]  Matti Pietikäinen,et al.  Multiresolution Gray-Scale and Rotation Invariant Texture Classification with Local Binary Patterns , 2002, IEEE Trans. Pattern Anal. Mach. Intell..

[16]  Pragati Kapoor,et al.  Image Segmentation and Asymmetry Analysis of Breast Thermograms for Tumor Detection , 2012 .

[17]  Tanya Lee,et al.  A Comparative Review of Thermography as a Breast Screening Technique , 2008 .

[18]  H. Pourghassem,et al.  Signature Identification Using Dynamic and HMM Features and KNN Classifier , 2013, 2013 International Conference on Communication Systems and Network Technologies.

[19]  Pragati Kapoor,et al.  Real Time Intelligent Thermal Analysis Approach for Early Diagnosis of Breast Cancer , 2010 .

[20]  L. Esserman,et al.  Efficacy of computerized infrared imaging analysis to evaluate mammographically suspicious lesions. , 2003, AJR. American journal of roentgenology.

[21]  Hossein Pourghassem,et al.  Clavulanic acid production estimation based on color and structural features of streptomyces clavuligerus bacteria using self-organizing map and genetic algorithm , 2014, Comput. Methods Programs Biomed..

[22]  Qolamreza R. Razlighi,et al.  Computation of Image Spatial Entropy Using Quadrilateral Markov Random Field , 2009, IEEE Transactions on Image Processing.

[23]  Gerald Schaefer,et al.  Thermography based breast cancer analysis using statistical features and fuzzy classification , 2009, Pattern Recognit..

[24]  Robert P. Sheridan,et al.  Random Forest: A Classification and Regression Tool for Compound Classification and QSAR Modeling , 2003, J. Chem. Inf. Comput. Sci..

[25]  Caro Lucas,et al.  Estimating the Mutual Information Between Bilateral Breast in Thermograms Using Nonparametric Windows , 2010, Journal of Medical Systems.

[26]  E. Y. K. Ng,et al.  Application of K- and Fuzzy c-Means for Color Segmentation of Thermal Infrared Breast Images , 2010, Journal of Medical Systems.

[27]  Monique Frize,et al.  Processing of thermal images to detect breast cancer: comparison with previous work , 2002, Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology.

[28]  N. M. Nandhitha,et al.  Image Processing Techniques and Neural Networks for Automated Cancer Analysis from Breast Thermographs-A Review , 2012 .

[29]  Hossein Pourghassem,et al.  Optimal Query-Based Relevance Feedback in Medical Image Retrieval Using Score Fusion-Based Classification , 2014, Journal of Digital Imaging.

[30]  Hossein Pourghassem,et al.  A framework for medical image retrieval using merging-based classification with dependency probability-based relevance feedback , 2013 .

[31]  Qing Wang,et al.  Morphological measurement of localized temperature increase amplitudes in breast infrared thermograms and its clinical application , 2008, Biomed. Signal Process. Control..

[32]  Shinto Eguchi,et al.  Image classification based on Markov random field models with Jeffreys divergence , 2006 .

[33]  E Y Ng,et al.  Statistical analysis of healthy and malignant breast thermography. , 2001, Journal of medical engineering & technology.

[34]  Nico Nagelkerke,et al.  Developing a Discrimination Rule between Breast Cancer Patients and Controls Using Proteomics Mass Spectrometric Data: A Three-Step Approach , 2008, Statistical applications in genetics and molecular biology.

[35]  Mohammad Ataei,et al.  Nonlinear analysis using Lyapunov exponents in breast thermograms to identify abnormal lesions , 2012 .

[36]  Vijay K. Jain,et al.  Markov random field for tumor detection in digital mammography , 1995, IEEE Trans. Medical Imaging.

[37]  M. Frize,et al.  Processing thermal images to detect breast cancer and assess pain , 2003, 4th International IEEE EMBS Special Topic Conference on Information Technology Applications in Biomedicine, 2003..

[38]  H. Qi,et al.  Detecting breast cancer from infrared images by asymmetry analysis , 2000, Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143).

[39]  Bryan F. Jones,et al.  A reappraisal of the use of infrared thermal image analysis in medicine , 1998, IEEE Transactions on Medical Imaging.

[40]  Mark Rosen,et al.  A Multichannel Markov Random Field Framework for Tumor Segmentation With an Application to Classification of Gene Expression-Based Breast Cancer Recurrence Risk , 2013, IEEE Transactions on Medical Imaging.

[41]  A. Jemal,et al.  Cancer Statistics, 2010 , 2010, CA: a cancer journal for clinicians.