Thiopurine pharmacogenetics in leukemia: Correlation of erythrocyte thiopurine methyltransferase activity and 6‐thioguanine nucleotide concentrations
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R. Weinshilboum | J. Lilleyman | L. Lennard | J. van Loon | Lynne Lennard | Jon A Van Loon | John S Lilleyman | Richard M Weinshilboum
[1] R. Weinshilboum,et al. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. , 1980, American journal of human genetics.
[2] R. Thomas,et al. AZATHIOPRINE AND SEVERE BONE MARROW DEPRESSION , 1986, The Lancet.
[3] R. Weinshilboum,et al. Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties. , 1978, Clinica chimica acta; international journal of clinical chemistry.
[4] D. Tidd,et al. A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine. , 1974, Cancer research.
[5] F. James Rohlf,et al. Biometry: The Principles and Practice of Statistics in Biological Research , 1969 .
[6] J. Maddocks,et al. Assay of 6‐thioguanine nucleotide, a major metabolite of azathioprine, 6‐mercaptopurine and 6‐thioguanine, in human red blood cells , 1983, The Journal of pharmacy and pharmacology.
[7] J. Chessells. Risks and benefits of intensive treatment of acute leukaemia. , 1985, Archives of disease in childhood.
[8] R. Weinshilboum,et al. Thiopurine methyltransferase. Aromatic thiol substrates and inhibition by benzoic acid derivatives. , 1983, Molecular pharmacology.
[9] J. Lilleyman,et al. Childhood leukaemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia. , 1983, British journal of clinical pharmacology.
[10] R. Weinshilboum. Human pharmacogenetics of methyl conjugation. , 1984, Federation proceedings.
[11] R. Weinshilboum,et al. Thiol S‐methylation in uremia: Erythrocyte enzyme activities and plasma inhibitors , 1980, Clinical pharmacology and therapeutics.
[12] C. Remy. Metabolism of thiopyrimidines and thiopurines. S-Methylation with S-adenosylmethionine transmethylase and catabolism in mammalian tissues. , 1963, The Journal of biological chemistry.
[13] C. Brown,et al. Azathioprine metabolism in kidney transplant recipients. , 1984, British journal of clinical pharmacology.
[14] R. Weinshilboum,et al. Cephalosporin-induced hypoprothrombinemia: possible role for thiol methylation of 1-methyltetrazole-5-thiol and 2-methyl-1,3,4-thiadiazole-5-thiol. , 1985, The Journal of pharmacology and experimental therapeutics.
[15] R. Aur,et al. Drug dosage and remission duration in childhood lymphocytic leukemia , 1971, Cancer.
[16] J. Maddocks,et al. Assay of thioinosinic acid, an active metabolite of azathioprine, in human lymphocytes. , 1980, British journal of clinical pharmacology.
[17] R. Weinshilboum. ‘Methylator status’ and assessment of variation in drug metabolism , 1980 .
[18] M. Murphy,et al. Severe megaloblastic anaemia associated with abnormal azathioprine metabolism. , 1984, British journal of clinical pharmacology.
[19] R. Weinshilboum,et al. Thiopurine methyltransferase: structure-activity relationships for benzoic acid inhibitors and thiophenol substrates. , 1986, Journal of medicinal chemistry.
[20] R. Weinshilboum,et al. Pharmacogenetics of human thiopurine methyltransferase: kidney-erythrocyte correlation and immunotitration studies. , 1982, The Journal of pharmacology and experimental therapeutics.
[21] A. Sartorelli,et al. Antineoplastic and Immunosuppressive Agents: Part I , 1974 .