Online Optic Disk Segmentation Using Fractals

Optic disk segmentation plays a key role in the mass screening of individuals with diabetic retinopathy and glaucoma ailments. An efficient hardware-based algorithm for optic disk localization and segmentation would aid for developing an automated retinal image analysis system for real time applications. Herein, TMS320C6416DSK DSP board pixel intensity based fractal analysis algorithm for an automatic localization and segmentation of the optic disk is reported. The experiment has been performed on color and fluorescent angiography retinal fundus images. Initially, the images were pre-processed to reduce the noise and enhance the quality. The retinal vascular tree of the image was then extracted using canny edge detection technique. Finally, a pixel intensity based fractal analysis is performed to segment the optic disk by tracing the origin of the vascular tree. The proposed method is examined on three publicly available data sets of the retinal image and also with the data set obtained from an eye clinic. The average accuracy achieved is 96.2%. To the best of the knowledge, this is the first work reporting the use of TMS320C6416DSK DSP board and pixel intensity based fractal analysis algorithm for an automatic localization and segmentation of the optic disk. This will pave the way for developing devices for detection of retinal diseases in the future. Keywords—Color retinal fundus images, Diabetic retinopathy, Fluorescein angiography retinal fundus images, Fractal analysis.

[1]  Aliaa A. A. Youssif,et al.  Optic Disc Detection From Normalized Digital Fundus Images by Means of a Vessels' Direction Matched Filter , 2008, IEEE Transactions on Medical Imaging.

[2]  Xiangjian He,et al.  Canny edge detection on a virtual hexagonal image structure , 2009, 2009 Joint Conferences on Pervasive Computing (JCPC).

[3]  T. Chaichana,et al.  Edge Detection of the Optic Disc in Retinal Images Based on Identification of a Round Shape , 2008, 2008 International Symposium on Communications and Information Technologies.

[4]  Ahmed S. Fahmy,et al.  Ultrafast optic disc localization using projection of image features , 2009, 2009 16th IEEE International Conference on Image Processing (ICIP).

[5]  R S Harwerth,et al.  Experimental glaucoma in primates: changes in cytochrome oxidase blobs in V1 cortex. , 2001, Investigative ophthalmology & visual science.

[6]  E. Kodeekha,et al.  Brute Force Method for Lot Streaming in FMS Scheduling Problems , 2007, 2007 11th International Conference on Intelligent Engineering Systems.

[7]  David R. Bull,et al.  Retinal image registration based on multiscale products and optic disc detection , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[8]  Roberto Brunelli Optimal histogram partitioning using a simulated annealing technique , 1992, Pattern Recognit. Lett..

[9]  M.A. Ullah,et al.  Automatic Extraction of Features from Retinal Fundus Image , 2007, 2007 International Conference on Information and Communication Technology.

[10]  Karel J. Zuiderveld,et al.  Contrast Limited Adaptive Histogram Equalization , 1994, Graphics Gems.

[11]  Sh Gharibzadeh,et al.  The new approach to automatic detection of Optic Disc from non-dilated retinal images , 2010, 2010 17th Iranian Conference of Biomedical Engineering (ICBME).

[12]  Yan Lindsay Sun,et al.  Detect of optic disc center based on Gaussian vessel detector and tangent information transform , 2011, 2011 4th International Conference on Biomedical Engineering and Informatics (BMEI).

[13]  Jean Vuillemin Fast linear Hough transform , 1994, Proceedings of IEEE International Conference on Application Specific Array Processors (ASSAP'94).

[14]  Mira Park,et al.  Locating the Optic Disc in Retinal Images , 2006, International Conference on Computer Graphics, Imaging and Visualisation (CGIV'06).

[15]  G. Landini,et al.  Local Connected Fractal Dimensions and Lacunarity Analyses of 60 ° Fluorescein Angiograms , 2005 .

[16]  J. Burleson,et al.  Pixel intensity and fractal analyses: detecting osteoporosis in perimenopausal and postmenopausal women by using digital panoramic images. , 2006, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[17]  Rached Tourki,et al.  Automated optic disc detection in retinal images by applying region-based active aontour model in a variational level set formulation , 2012, 2012 International Conference on Computer Vision in Remote Sensing.

[18]  Enrico Grisan,et al.  Detection of optic disc in retinal images by means of a geometrical model of vessel structure , 2004, IEEE Transactions on Medical Imaging.

[19]  Pascale Massin,et al.  A contribution of image processing to the diagnosis of diabetic retinopathy-detection of exudates in color fundus images of the human retina , 2002, IEEE Transactions on Medical Imaging.

[20]  Nasser Kehtarnavaz,et al.  Computationally efficient optic nerve head detection in retinal fundus images , 2014, Biomed. Signal Process. Control..