Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose-response relationships.
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Stephen D Dertinger | Steven M Bryce | Jeffrey C Bemis | J. Bemis | S. Dertinger | Steven M. Bryce | Svetlana L Avlasevich | Souk Phonethepswath | Svetlana L. Avlasevich | S. Phonethepswath
[1] C. Cox,et al. Threshold dose-response models in toxicology. , 1987, Biometrics.
[2] A Elhajouji,et al. Indications for a threshold of chemically‐induced aneuploidy in vitro in human lymphocytes , 1995, Environmental and molecular mutagenesis.
[3] M. Kirsch‐Volders,et al. Flow cytometry peripheral blood micronucleus test in vivo: Determination of potential thresholds for aneuploidy induced by spindle poisons , 2009, Environmental and molecular mutagenesis.
[4] J. Bemis,et al. Miniaturized flow cytometry‐based CHO‐K1 micronucleus assay discriminates aneugenic and clastogenic modes of action , 2011, Environmental and molecular mutagenesis.
[5] Lutz Müller,et al. A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity. , 2006, Regulatory toxicology and pharmacology : RTP.
[6] S. Hecht. Bleomycin: new perspectives on the mechanism of action. , 2000, Journal of natural products.
[7] H. Kay. Environmental Health Criteria , 1980 .
[8] F. Nesslany,et al. Study of oxidative DNA damage in TK6 human lymphoblastoid cells by use of the in vitro micronucleus test: Determination of No-Observed-Effect Levels. , 2009, Mutation research.
[9] R. W. Lutz,et al. Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose-response relationships, exemplified for mutagenicity data. , 2009, Mutation research.
[10] M. Nüsse,et al. Chapter 9 Measurement of Micronuclei by Flow Cytometry , 1994 .
[11] S Albertini,et al. Aneuploidy: a report of an ECETOC task force. , 1998, Mutation research.
[12] Stephen D Dertinger,et al. In vitro micronucleus scoring by flow cytometry: Differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability , 2006, Environmental and molecular mutagenesis.
[13] S. Dertinger,et al. Practical threshold for micronucleated reticulocyte induction observed for low doses of mitomycin C, Ara-C and colchicine. , 2006, Mutagenesis.
[14] Lutz Müller,et al. In vivo studies in the mouse to define a threshold for the genotoxicity of EMS and ENU. , 2009, Mutation research.
[15] E. Moustacchi,et al. DNA damage and repair: consequences on dose-responses. , 2000, Mutation research.
[16] Stephen D Dertinger,et al. In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity. , 2007, Mutation research.
[17] 岩崎 民子. SOURCES AND EFFECTS OF IONIZING RADIATION : United Nations Scientific Committee on the Effects of Atomic Radiation UNSCEAR 2000 Report to the General Assembly, with Scientific Annexes , 2002 .
[18] Fagen Zhang,et al. Dose-response and operational thresholds/NOAELs for in vitro mutagenic effects from DNA-reactive mutagens, MMS and MNU. , 2009, Mutation research.
[19] M. Nüsse,et al. Flow cytometric analysis of micronuclei found in cells after irradiation. , 1984, Cytometry.
[20] G. Jenkins,et al. Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens. , 2007, Cancer research.
[21] Lutz Müller,et al. Ethyl methanesulfonate toxicity in Viracept--a comprehensive human risk assessment based on threshold data for genotoxicity. , 2009, Toxicology letters.
[22] D. Skibinski,et al. Non-linear dose-response of DNA-reactive genotoxins: recommendations for data analysis. , 2009, Mutation research.
[23] A Elhajouji,et al. Concepts of threshold in mutagenesis and carcinogenesis. , 2000, Mutation research.
[24] L. Müller,et al. MNT and MutaMouse studies to define the in vivo dose response relations of the genotoxicity of EMS and ENU. , 2009, Toxicology letters.
[25] H Greim,et al. International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC publication no. 10. Review of the evidence for the presence or absence of thresholds in the induction of genetic effects by genotoxic chemicals. , 1983, Mutation research.