Combinatorial Chemistry andCombinatorialTechnology(CC/CT) are a new interdisciplinary field joining computer-assistedcombinatorialchemistrywithautomatedparallelsyn-thesis of chemical ilibrariesi followed by automated screen-ing.The main purpose of computer assisted combinatorialchemistry is to generate thousands structurally diverse com-poundsaslibraries,maximisingtheirdiversity,whicharethenconsidered in an experimental parallel automated synthesisandscreeningonthebasisoftheirproperties.ThekeyissueistointegrateallimportantstepsofCC/CTinasingle,multidis-ciplinary approach.Thisnascenttechnologyalreadyproducedmorenewcom-pounds in just a few years than the pharmaceutical industrydidin itsentire history.Combinatorial chemistry has turned traditional chemistryupsidedown.Itrequiredchemistsnottothinkintermsofsyn-thesizing single, well-characterized compounds but in termsof simultaneously synthesizing large populations of com-pounds.Italsorequiredthatthosepeopleinvolvedwithinfor-mation management and computational chemistry systemsaddressthese same issuesas the chemists.WhileCC/CThadthegreatestimpactonthedrugindustry,combinatorialmethodsneednotberestrictedtopharmaceuti-calapplications.Wheneverhighnumbersofcompoundshaveto be prepared for testing, this technique can be used. Forexample, agricultural research, new materials and new cata-lysts research and development stand to gain from this tech-nology.However,forthetimebeing,mainemphasisisstillonpharmaceutical research. Most major pharmaceutical compa-nies are active in the field. It is generally accepted that themethod has a great potential for finding leads in the drugdiscoveryprocesswherethetechnologyisexpectedtocontri-bute to the reduction in time and cost.Many countries have emphasized the urgent need to getacquainted with Combinatorial Technologies in order to en-ablelocalenterprisestoremaincompetitiveandeconomicallyviableinthecomingdecadesandgainexpertiseonapplicationpracticesofcombinatorialtechnology.Inviewofglobalcom-petition, CC/CT together with molecular modeling may beconsideredaspowerfultoolsfortheimplementationand/ortheincreaseofacountryiscapabilitiesindrugdesign,agrochem-istry, new materials and new catalysts. The above considera-tions become even more significant if it is taken into accountthatmanycountrieshaveabundantnaturalresourceswhicharepresentlywellbelowtheirproperexploitation.Combinatorialchemistry can enhancethe potential of theseresources.