Clinical studies of induction agents. XV. A comparison of the cumulative effects of thiopentone, methohexitone and propidid.

SUMMARY Thiopentone, methohexitone and propanidid have been given by intermittent dosage as main agent for a series of body surface operations. The requirements over the first hour show a marked falling off with the barbiturates but little decline with propanidid. This supports the experimental findings that propanidid is rapidly destroyed in the body whereas the other agents are translocated into storage depots.

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