Lowering serum urate does not improve endothelial function in patients with type 2 diabetes

[1]  F. Zannad,et al.  Endothelial dysfunction and type 2 diabetes , 2008 .

[2]  T. Rabelink,et al.  Endothelial function and dysfunction: testing and clinical relevance. , 2007, Circulation.

[3]  A. Struthers,et al.  High-Dose Allopurinol Improves Endothelial Function by Profoundly Reducing Vascular Oxidative Stress and Not by Lowering Uric Acid , 2006, Circulation.

[4]  M. Tuck,et al.  Uric acid and the vasculature , 2006, Current hypertension reports.

[5]  C. Zoccali,et al.  Uric acid and endothelial dysfunction in essential hypertension. , 2006, Journal of the American Society of Nephrology : JASN.

[6]  L. Bouter,et al.  Endothelial Dysfunction and Low-Grade Inflammation Explain Much of the Excess Cardiovascular Mortality in Individuals With Type 2 Diabetes: The Hoorn Study , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[7]  T. Nakagawa,et al.  Serum uric acid: a risk factor and a target for treatment? , 2006, Journal of the American Society of Nephrology : JASN.

[8]  T. Rabelink,et al.  Endothelial nitric oxide synthase: host defense enzyme of the endothelium? , 2005, Arteriosclerosis, thrombosis, and vascular biology.

[9]  C. Perry,et al.  Rasburicase: a review of its use in the management of anticancer therapy-induced hyperuricaemia. , 2006, Drugs.

[10]  K. Kotani,et al.  Status of endothelial dependent vasodilation in patients with hyperuricemia. , 2005, The American journal of cardiology.

[11]  In-kyu Lee,et al.  Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells. , 2005, Journal of the American Society of Nephrology : JASN.

[12]  D. Chemla,et al.  Cardiovascular outcome of patients with abnormal coronary vasomotion and normal coronary arteriography is worse in type 2 diabetes mellitus than in arterial hypertension: a 10 year follow-up study. , 2005, Atherosclerosis.

[13]  U. R. Kuppusamy,et al.  Glycaemic control in relation to xanthine oxidase and antioxidant indices in Malaysian Type 2 diabetes patients , 2005, Diabetic medicine : a journal of the British Diabetic Association.

[14]  D. Giugliano,et al.  Effect of Atorvastatin and Irbesartan, Alone and in Combination, on Postprandial Endothelial Dysfunction, Oxidative Stress, and Inflammation in Type 2 Diabetic Patients , 2005, Circulation.

[15]  E. Block,et al.  Hyperuricemia induces endothelial dysfunction. , 2005, Kidney international.

[16]  Gian Paolo Rossi,et al.  Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension. , 2005, Journal of hypertension.

[17]  M. Quon,et al.  Additive Beneficial Effects of Losartan Combined With Simvastatin in the Treatment of Hypercholesterolemic, Hypertensive Patients , 2004, Circulation.

[18]  G. Rosano,et al.  Effect of hyperuricemia upon endothelial function in patients at increased cardiovascular risk. , 2004, The American journal of cardiology.

[19]  M. Tarpey,et al.  Binding of Xanthine Oxidase to Glycosaminoglycans Limits Inhibition by Oxypurinol* , 2004, Journal of Biological Chemistry.

[20]  J. Hare,et al.  Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications , 2004, The Journal of physiology.

[21]  Michael T. Watkins,et al.  Predictive value of noninvasivelydetermined endothelial dysfunction for long-term cardiovascular events inpatients with peripheral vascular disease , 2003 .

[22]  D. Webb,et al.  Noninvasive assessment of arterial stiffness and risk of atherosclerotic events. , 2003, Arteriosclerosis, thrombosis, and vascular biology.

[23]  H. Koyama,et al.  Preferential stiffening of central over peripheral arteries in type 2 diabetes. , 2003, Diabetes.

[24]  W. Haynes,et al.  Xanthine Oxidase Inhibition Reverses Endothelial Dysfunction in Heavy Smokers , 2003, Circulation.

[25]  R. Henning,et al.  Protective role of endothelial nitric oxide synthase , 2003, The Journal of pathology.

[26]  P. Raskin,et al.  Report of the expert committee on the diagnosis and classification of diabetes mellitus. , 1999, Diabetes care.

[27]  Seil Oh,et al.  Effects of acute hyperglycemia on endothelium-dependent vasodilation in patients with diabetes mellitus or impaired glucose metabolism. , 2003, Endothelium : journal of endothelial cell research.

[28]  M. Watkins,et al.  Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events in patients with peripheral vascular disease. , 2003, Journal of the American College of Cardiology.

[29]  D. Webb,et al.  Uric acid concentrations and the mechanisms of cardiovascular disease. , 2002, European heart journal.

[30]  M. Bots,et al.  Aggressive lipid lowering does not improve endothelial function in type 2 diabetes: the Diabetes Atorvastatin Lipid Intervention (DALI) Study: a randomized, double-blind, placebo-controlled trial. , 2002, Diabetes care.

[31]  Rainer Hambrecht,et al.  Effects of Xanthine Oxidase Inhibition With Allopurinol on Endothelial Function and Peripheral Blood Flow in Hyperuricemic Patients With Chronic Heart Failure: Results From 2 Placebo-Controlled Studies , 2002, Circulation.

[32]  G. Seghieri,et al.  Increase in serum uric acid is selectively associated with stroke in type 2 diabetes. , 2002, Diabetes care.

[33]  H. Yki-Järvinen,et al.  Endothelial dysfunction in human diabetes , 2002, Current diabetes reports.

[34]  M. O'Rourke,et al.  Prospective Evaluation of a Method for Estimating Ascending Aortic Pressure From the Radial Artery Pressure Waveform , 2001, Hypertension.

[35]  F. Zannad,et al.  Endothelial dysfunction and type 2 diabetes. Part 1: physiology and methods for exploring the endothelial function. , 2001, Diabetes & metabolism.

[36]  Jing Fang,et al.  Serum Uric Acid and Cardiovascular Mortality: The NHANES I Epidemiologic Follow-up Study, 1971-1992 , 2000 .

[37]  M. Rich.  Uric acid: is it a risk factor for cardiovascular disease? , 2000, The American journal of cardiology.

[38]  A. Morris,et al.  Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension. , 2000, Hypertension.

[39]  M. Alderman,et al.  Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. , 2000, JAMA.

[40]  J. Pinkney,et al.  Endothelial dysfunction in Type 1 diabetes mellitus: relationship with LDL oxidation and the effects of vitamin E , 1999, Diabetic medicine : a journal of the British Diabetic Association.

[41]  G. Zhao,et al.  Reduced coronary NO production in conscious dogs after the development of alloxan-induced diabetes. , 1999, The American journal of physiology.

[42]  D. Webb,et al.  Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis , 1998, Journal of hypertension.

[43]  P. Poole‐Wilson,et al.  Uric acid in chronic heart failure: a marker of chronic inflammation. , 1998, European heart journal.

[44]  D. Winfield,et al.  Efficacy of urate oxidase (uricozyme) in tumour lysis induced urate nephropathy. , 1998, Clinical and laboratory haematology.

[45]  C. Patte,et al.  Advances in the management of malignancy-associated hyperuricaemia. , 1998, British Journal of Cancer.

[46]  L. Niskanen,et al.  Serum uric acid is a strong predictor of stroke in patients with non-insulin-dependent diabetes mellitus. , 1998, Stroke.

[47]  D. Lyons,et al.  Impairment and restoration of nitric oxide-dependent vasodilation in cardiovascular disease. , 1997, International journal of cardiology.

[48]  F. Mee,et al.  Evaluation of three devices for self-measurement of blood pressure according to the revised British Hypertension Society Protocol: the Omron HEM-705CP, Philips HP5332, and Nissei DS-175. , 1996, Blood pressure monitoring.

[49]  K. Takazawa,et al.  Estimation of ascending aortic pressure from radial arterial pressure using a generalised transfer function. , 1996, Zeitschrift fur Kardiologie.

[50]  P Vallance,et al.  Measuring forearm blood flow and interpreting the responses to drugs and mediators. , 1995, Hypertension.

[51]  P. Whincup,et al.  Prospective study of risk factors for development of non-insulin dependent diabetes in middle aged British men , 1995, BMJ.

[52]  R. Radi,et al.  Physiologic Levels of Uric Acid Inhibit Xanthine Oxidase in Human Plasma , 1993, Pediatric Research.

[53]  W. Rathmann,et al.  Association of elevated serum uric acid with coronary heart disease in diabetes mellitus. , 1993, Diabete & metabolisme.

[54]  R. Radi,et al.  Inhibition of xanthine oxidase by uric acid and its influence on superoxide radical production. , 1992, Biochimica et biophysica acta.