Integrins as Signal Transducing Receptors

[1]  M. Schwartz,et al.  Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown , 1993, The Journal of cell biology.

[2]  M. Schwartz,et al.  Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms , 1993, The Journal of cell biology.

[3]  J. Brugge,et al.  Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets , 1993, Molecular and cellular biology.

[4]  Jang-Soo Chun,et al.  Requirement for diacylglycerol and protein kinase C in HeLa cell-substratum adhesion and their feedback amplification of arachidonic acid production for optimum cell spreading. , 1993, Molecular biology of the cell.

[5]  M. Schwartz,et al.  Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium , 1993, The Journal of cell biology.

[6]  J. Parsons,et al.  Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets , 1992, The Journal of cell biology.

[7]  C. Turner,et al.  Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly , 1992, The Journal of cell biology.

[8]  C. Klee,et al.  Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. , 1992, Science.

[9]  S. Haskill,et al.  Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[10]  A. Levinson,et al.  Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells. , 1992, Molecular biology of the cell.

[11]  D. Shalloway,et al.  Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation , 1992, Nature.

[12]  C. Lechene,et al.  Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[13]  B. Jacobson,et al.  Spreading of HeLa cells on a collagen substratum requires a second messenger formed by the lipoxygenase metabolism of arachidonic acid released by collagen receptor clustering. , 1992, Molecular biology of the cell.

[14]  M. Bissell,et al.  Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity , 1991, The Journal of cell biology.

[15]  R L Juliano,et al.  Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[16]  A. Kuramoto,et al.  Electrophysiological evidence that glycoprotein IIb-IIIa complex is involved in calcium channel activation on human platelet plasma membrane. , 1991, The Journal of biological chemistry.

[17]  C. Lechene,et al.  Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[18]  J. Barnwell,et al.  Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[19]  T. Springer,et al.  Multiple integrins share the ability to induce elevation of intracellular pH. , 1991, Experimental cell research.

[20]  T. Andersson,et al.  Calcium signaling capacity of the CD11b/CD18 integrin on human neutrophils. , 1991, Experimental cell research.

[21]  S. Haskill,et al.  Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity , 1991, Cell.

[22]  W. Schlegel,et al.  Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family , 1991, The Journal of cell biology.

[23]  F. Maxfield,et al.  Attachment to fibronectin or vitronectin makes human neutrophil migration sensitive to alterations in cytosolic free calcium concentration , 1991, The Journal of cell biology.

[24]  I. Olsson,et al.  Tumor necrosis factor-induced degranulation in adherent human neutrophils is dependent on CD11b/CD18-integrin-triggered oscillations of cytosolic free Ca2+. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[25]  J. Bixby,et al.  Extracellular matrix molecules and cell adhesion molecules induce neurites through different mechanisms , 1990, The Journal of cell biology.

[26]  J. Brugge,et al.  Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins , 1990, The Journal of cell biology.

[27]  R. Clark,et al.  Adherence-dependent increase in human monocyte PDGF(B) mRNA is associated with increases in c-fos, c-jun, and EGR2 mRNA , 1990, The Journal of cell biology.

[28]  D. Salant,et al.  Extracellular matrix regulates proliferation and phospholipid turnover in glomerular epithelial cells. , 1990, The American journal of physiology.

[29]  S. Farmer,et al.  Regulation of alpha 1 (I)-collagen gene expression in response to cell adhesion in Swiss 3T3 fibroblasts. , 1990, The Journal of biological chemistry.

[30]  J. Parsons,et al.  Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[31]  D. Ingber,et al.  Control of intracellular pH and growth by fibronectin in capillary endothelial cells , 1990, The Journal of cell biology.

[32]  R. Tucker,et al.  Cell shape and increased free cytosolic calcium [Ca2+]i induced by growth factors. , 1990, Cell calcium.

[33]  C. Lechene,et al.  pH regulation in spread cells and round cells. , 1990, The Journal of biological chemistry.

[34]  M. Hemler.  VLA proteins in the integrin family: structures, functions, and their role on leukocytes. , 1990, Annual review of immunology.

[35]  J. Frangioni,et al.  Cytoplasmic pH and anchorage-independent growth induced by v-Ki-ras, v-src or polyoma middle T. , 1990, Oncogene.

[36]  R. Pardi,et al.  Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets. , 1989, Journal of immunology.

[37]  M. Rybak,et al.  Ligand inhibition of the platelet glycoprotein IIb-IIIa complex function as a calcium channel in liposomes. , 1989, The Journal of biological chemistry.

[38]  C. Nathan,et al.  Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins , 1989, The Journal of cell biology.

[39]  Z. Werb,et al.  Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression , 1989, The Journal of cell biology.

[40]  S. Dedhar.  Signal transduction via the β1 integrins is a required intermediate in interleukin-1β induction of alkaline phosphatase activity in human osteosarcoma cells☆ , 1989 .

[41]  C. Wagener,et al.  Activation of the phosphatidylinositol cycle in spreading cells. , 1989, Experimental cell research.

[42]  C. Lechene,et al.  Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[43]  H. Yamamura,et al.  Thrombin and collagen induce rapid phosphorylation of a common set of cellular proteins on tyrosine in human platelets. , 1989, The Journal of biological chemistry.

[44]  J. Ferrell,et al.  Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[45]  S Grinstein,et al.  Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation. , 1989, Biochimica et biophysica acta.

[46]  S. Farmer,et al.  Cell adhesion induces expression of growth-associated genes in suspension-arrested fibroblasts. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[47]  R. Serrano,et al.  Increased pH and tumorigenicity of fibroblasts expressing a yeast proton pump , 1988, Nature.

[48]  L. Margolis,et al.  Intracellular pH and cell adhesion to solid substrate , 1988, FEBS letters.

[49]  E. Ruoslahti.  Fibronectin and its receptors. , 1988, Annual review of biochemistry.

[50]  L. Brass,et al.  Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[51]  Z. Werb,et al.  Reorganization of polymerized actin: a possible trigger for induction of procollagenase in fibroblasts cultured in and on collagen gels , 1986, The Journal of cell biology.

[52]  K. Burridge.  Substrate adhesions in normal and transformed fibroblasts organization and regulation of cytoskeletal membrane and extracellular matrix components at focal contacts , 1986 .

[53]  S. Wright,et al.  Communication between receptors for different ligands on a single cell: ligation of fibronectin receptors induces a reversible alteration in the function of complement receptors on cultured human monocytes , 1984, The Journal of cell biology.

[54]  Z. Werb,et al.  Changes in cell shape correlate with collagenase gene expression in rabbit synovial fibroblasts , 1984, The Journal of cell biology.

[55]  M J Bissell,et al.  How does the extracellular matrix direct gene expression? , 1982, Journal of theoretical biology.