Longitudinal changes in maternal corin and mid‐regional proatrial natriuretic peptide in women at risk of pre‐eclampsia

Corin, an atrial natriuretic peptide‐converting enzyme, has been found to promote trophoblast invasion and spiral artery remodeling. Yet, elevated maternal plasma atrial natriuretic peptide (ANP) and corin levels have been reported in pregnancies complicated by pre‐eclampsia (PE). The aim of this study was to investigate longitudinal changes in maternal plasma levels of corin and mid‐regional proatrial natriuretic peptide (MR‐PANP) in pregnancies that develop PE and gestational hypertension (GH).

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