Construction of 3,5-substituted 1,2,4-oxadiazole rings triggered by tetrabutylammonium hydroxide: a highly efficient and fluoride-free ring closure reaction of O-acylamidoximes

[1]  Sung‐Ho Jin,et al.  Synthesis of polymers containing 1,2,4‐oxadiazole as an electron‐acceptor moiety in their main chain and their solar cell applications , 2013 .

[2]  Jonas Boström,et al.  Oxadiazoles in medicinal chemistry. , 2012, Journal of medicinal chemistry.

[3]  Antonio Di Pascale,et al.  Structure and cytotoxicity of phidianidines A and B: first finding of 1,2,4-oxadiazole system in a marine natural product. , 2011, Organic letters.

[4]  D. Grigoriadis,et al.  Discovery of NBI-77860/GSK561679, a potent corticotropin-releasing factor (CRF1) receptor antagonist with improved pharmacokinetic properties. , 2010, Bioorganic & medicinal chemistry letters.

[5]  A. Pace,et al.  The new era of 1,2,4-oxadiazoles. , 2009, Organic & biomolecular chemistry.

[6]  M. Soares,et al.  Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents. , 2009, Bioorganic & medicinal chemistry.

[7]  P. Alagarsamy,et al.  PTSA-ZnCl2: an efficient catalyst for the synthesis of 1,2,4-oxadiazoles from amidoximes and organic nitriles. , 2009, The Journal of organic chemistry.

[8]  J. Barberá,et al.  New 1,2,4‐ and 1,3,4‐oxadiazole materials: synthesis, and mesomorphic and luminescence properties , 2006 .

[9]  P. Wagner,et al.  Oximes as intermediates or final products in reactions of nitroheteroarenes with nucleophiles in the presence of sodium methoxide-methanol system , 2003 .

[10]  A. Gangloff,et al.  Synthesis of 3,5-disubstituted-1,2,4-oxadiazoles using tetrabutylammonium fluoride as a mild and efficient catalyst , 2001 .

[11]  A. Pace,et al.  Fluoro heterocycles. A photochemical methodology for the synthesis of 3-amino- and 3-(N-alkylamino)-5-perfluoroalkyl-1,2,4-oxadiazoles , 2000 .

[12]  L. Terenius,et al.  Design, synthesis, and evaluation of Phe-Gly mimetics: heterocyclic building blocks for pseudopeptides. , 1999, Journal of medicinal chemistry.

[13]  K. Kubo,et al.  A new class of diacidic nonpeptide angiotensin II receptor antagonists: candesartan cilexetil. , 1999, Current pharmaceutical design.

[14]  T. Hirota,et al.  Polycyclic N-heterocyclic compounds. 55†. A novel reaction of N-(5,6-dihydro[1]benzothiepino[5,4-d]pyrimidin-4-yl)amidine or its amide oxime derivatives with hydroxylamine , 1999 .

[15]  G. Liang,et al.  An improved oxadiazole synthesis using peptide coupling reagents , 1996 .

[16]  J. C. Barnes,et al.  Novel 1, 2, 4-oxadiazoles as potent and selective histamine H3 receptor antagonists , 1996 .

[17]  C. Braestrup,et al.  Oxadiazoles as bioisosteric transformations of carboxylic functionalities. II , 1996 .

[18]  R. Grigg Asymmetric cascade 1,3-dipolar cycloaddition reactions of imines , 1995 .

[19]  U. Hacksell,et al.  Synthesis of 1,2,4-Oxadiazole-, 1,3,4-Oxadiazole-, and 1,2,4-Triazole-Derived Dipeptidomimetics , 1995 .

[20]  T. J. Nitz,et al.  Oxadiazoles as ester bioisosteric replacements in compounds related to disoxaril. Antirhinovirus activity. , 1994, Journal of medicinal chemistry.

[21]  J. Jung,et al.  Synthesis and thermal properties of copoly(1,4-arylene-1,2-4-oxadiazole)s with dimethyl substituent , 1992 .

[22]  S. Freedman,et al.  Synthesis and biological activity of 1,2,4-oxadiazole derivatives: highly potent and efficacious agonists for cortical muscarinic receptors. , 1990, Journal of medicinal chemistry.

[23]  S. Chiou,et al.  A simplified procedure for preparing 3,5-disubstituted-1,2,4-oxadiazoles by reaction of amidoximes with Acyl chlorides in pyridine solution , 1989 .

[24]  F. G. Bordwell,et al.  Equilibrium Acidities in Dimethyl Sulfoxide Solution , 1988 .

[25]  M. Krayushkin,et al.  Reaction of organic nitriles with benzamidoxime , 1986 .

[26]  E. Kawashima,et al.  Cyclization of O-Acetoacetylbenzamide Oxime Derivatives , 1982 .

[27]  David A. Wilson,et al.  Formation and thermal reaction of O-(N-acetylbenzimidoyl)benzamidoxime: comparison with the formation of 3,5-disubstituted 1,2,4-oxadiazoles from O-acetylarylamidoximes and O-aroylacetamidoximes , 1981 .

[28]  I. Kolthoff,et al.  Dissociation constants of uncharged and monovalent cation acids in dimethyl sulfoxide , 1968 .

[29]  F. Tiemann,et al.  Ueber Amidoxime und Azoxime , 1884 .