Retina Structure / Psychophysical Relationships in X-Linked Retinoschisis

Citation: Bennett LD, Wang Y-Z, Klein M, Pennesi ME, Jayasundera T, Birch DG. Structure/psychophysical relationships in X-linked retinoschisis. Invest Ophthalmol Vis Sci. 2016;57:332–337. DOI:10.1167/ iovs.15-18354 PURPOSE. To compare structural properties from spectral-domain optical coherence tomography (SDOCT) and psychophysical measures from a subset of patients enrolled in a larger multicenter natural history study of X-linked retinoschisis (XLRS). METHODS. A subset of males (n 1⁄4 24) participating in a larger natural history study of XLRS underwent high-resolution SDOCT. Total retina (TR) thickness and outer segment (OS) thickness were measured manually. Shape discrimination hyperacuity (SDH) and contour integration perimetry (CIP) were performed on an iPad with the myVisionTrack application. Sensitivity was measured with fundus-guided perimetry (4-2 threshold testing strategy; 10-2 grid, spot size 3, 68 points). Correlation was determined with Pearson’s r correlation. Values are presented as the mean 6 SD.

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