Impact of rapid near-patient STI testing on service delivery outcomes in an integrated sexual health service in the United Kingdom: a controlled interrupted time series study

Objectives To evaluate the impact of a new clinic-based rapid sexually transmitted infection testing, diagnosis and treatment service on healthcare delivery and resource needs in an integrated sexual health service. Design Controlled interrupted time series study. Setting Two integrated sexual health services (SHS) in UK: Unity Sexual Health in Bristol, UK (intervention site) and Croydon Sexual Health in London (control site). Participants Electronic patient records for all 58 418 attendances during the period 1 year before and 1 year after the intervention. Intervention Introduction of an in-clinic rapid testing system for gonorrhoea and chlamydia in combination with revised treatment pathways. Outcome measures Time-to-test notification, staff capacity, cost per episode of care and overall service costs. We also assessed rates of gonorrhoea culture swabs, follow-up attendances and examinations. Results Time-to-notification and the rate of gonorrhoea swabs significantly decreased following implementation of the new system. There was no evidence of change in follow-up visits or examination rates for patients seen in clinic related to the new system. Staff capacity in clinics appeared to be maintained across the study period. Overall, the number of episodes per week was unchanged in the intervention site, and the mean cost per episode decreased by 7.5% (95% CI 5.7% to 9.3%). Conclusions The clear improvement in time-to-notification, while maintaining activity at a lower overall cost, suggests that the implementation of clinic-based testing had the intended impact, which bolsters the case for more widespread rollout in sexual health services.

[1]  A. Lorenc,et al.  What can be learnt from a qualitative evaluation of implementing a rapid sexual health testing, diagnosis and treatment service? , 2021, BMJ Open.

[2]  S. Katikireddi,et al.  Conceptualising natural and quasi experiments in public health , 2020, BMC Medical Research Methodology.

[3]  W. Hollingworth,et al.  Modelling patient flows and resource use within a sexual health clinic through discrete event simulation to inform service redesign , 2020, BMJ Open.

[4]  S. Sadiq,et al.  2018 UK national guideline for the management of infection with Neisseria gonorrhoeae , 2019, International journal of STD & AIDS.

[5]  K. Looker,et al.  Online testing for sexually transmitted infections: A whole systems approach to predicting value , 2019, PloS one.

[6]  James Lopez Bernal,et al.  The use of controls in interrupted time series studies of public health interventions. , 2018, International journal of epidemiology.

[7]  K. Looker,et al.  Web-Based Activity Within a Sexual Health Economy: Observational Study , 2018, Journal of medical Internet research.

[8]  N. Longford,et al.  Rapid testing and treatment for sexually transmitted infections improve patient care and yield public health benefits , 2017, International journal of STD & AIDS.

[9]  E. Harding-Esch,et al.  Modelling-based evaluation of the costs, benefits and cost-effectiveness of multipathogen point-of-care tests for sexually transmitted infections in symptomatic genitourinary medicine clinic attendees , 2017, BMJ Open.

[10]  C. White Sexual health services on the brink , 2017, British Medical Journal.

[11]  J. Macleod,et al.  Cross-sectional study to evaluate Trichomonas vaginalis positivity in women tested for Neisseria gonorrhoeae and Chlamydia trachomatis, attending genitourinary medicine and primary care clinics in Bristol, South West England , 2017, Sexually Transmitted Infections.

[12]  M. Price,et al.  The natural history of Chlamydia trachomatis infection in women: a multi-parameter evidence synthesis. , 2016, Health technology assessment.

[13]  J. Horwood,et al.  Sexual health risks, service use, and views of rapid point-of-care testing among men who have sex with men attending saunas: a cross-sectional survey , 2015, International journal of STD & AIDS.

[14]  J. Kaldor,et al.  “I Do Feel Like a Scientist at Times”: A Qualitative Study of the Acceptability of Molecular Point-Of-Care Testing for Chlamydia and Gonorrhoea to Primary Care Professionals in a Remote High STI Burden Setting , 2015, PloS one.

[15]  K. Turner,et al.  Mapping patient pathways and estimating resource use for point of care versus standard testing and treatment of chlamydia and gonorrhoea in genitourinary medicine clinics in the UK , 2014, BMJ Open.

[16]  A. Miners Is nucleic acid amplification point-of-care testing for chlamydia and gonorrhoea cost-effective? , 2014, Sexually Transmitted Infections.

[17]  K. Turner,et al.  An early evaluation of clinical and economic costs and benefits of implementing point of care NAAT tests for Chlamydia trachomatis and Neisseria gonorrhoea in genitourinary medicine clinics in England , 2013, Sexually Transmitted Infections.

[18]  Jill S. Huppert,et al.  Point-of-care tests for sexually transmissible infections: what do 'end users' want? , 2013, Sexual health.

[19]  A. Miners,et al.  Testing for sexually transmitted infections among students: a discrete choice experiment of service preferences , 2013, BMJ Open.

[20]  J. Cairns,et al.  Understanding patient choices for attending sexually transmitted infection testing services: a qualitative study , 2012, Sexually Transmitted Infections.

[21]  P. Aggleton,et al.  Promoting the uptake of HIV testing among men who have sex with men: systematic review of effectiveness and cost-effectiveness , 2011, Sexually Transmitted Infections.

[22]  Dean Keith Simonton,et al.  Cross-sectional time-series experiments: Some suggested statistical analyses , 1977 .