The genetic impact of the Q551R interleukin-4 receptor alpha polymorphism for aggressive or chronic periodontitis and the occurrence of periodontopathic bacteria.

[1]  R. Bödeker,et al.  Production of Interleukin‐13 is Influenced by the Interleukin‐4 −34TT and −590TT Genotype in Patients with Aggressive Periodontitis , 2011, Scandinavian journal of immunology.

[2]  K. Ho,et al.  Investigation of interleukin-13 gene polymorphisms in individuals with chronic and generalized aggressive periodontitis in a Taiwanese (Chinese) population. , 2010, Journal of periodontal research.

[3]  B. Holtfreter,et al.  Prevalence of periodontal disease and treatment demands based on a German dental survey (DMS IV). , 2010, Journal of clinical periodontology.

[4]  J. Cirelli,et al.  Polymorphisms and haplotypes in the interleukin-4 gene are associated with chronic periodontitis in a Brazilian population. , 2010, Journal of periodontology.

[5]  J. Klapproth,et al.  Interleukin-2 -330 and 166 gene polymorphisms in relation to aggressive or chronic periodontitis and the presence of periodontopathic bacteria. , 2009, Journal of periodontal research.

[6]  P. Augustin,et al.  The association of interleukin-4 haplotypes with chronic periodontitis in a Czech population. , 2008, Journal of periodontology.

[7]  R. Bödeker,et al.  Single-nucleotide polymorphisms in the IL-4 and IL-13 promoter region in aggressive periodontitis. , 2007, Journal of clinical periodontology.

[8]  M. Tonetti,et al.  Gene Polymorphisms and the Prevalence of Key Periodontal Pathogens , 2007, Journal of dental research.

[9]  F. Serio,et al.  The contribution of interleukin-13 and -15 to the cytokine network within normal and diseased gingiva. , 2007, Journal of periodontology.

[10]  Tetsuo Kobayashi,et al.  The role of genetic polymorphisms in periodontitis. , 2007, Periodontology 2000.

[11]  L. Padyukov,et al.  Association of the -159 CD14 gene polymorphism and lack of association of the -308 TNFA and Q551R IL-4RA polymorphisms with severe chronic periodontitis in Swedish Caucasians. , 2005, Journal of clinical periodontology.

[12]  B. Żelazowska,et al.  Evaluation of selected peripheral blood leukocyte functions in patients with various forms of periodontal disease. , 2004, Archivum immunologiae et therapiae experimentalis.

[13]  RAM R. Singh,et al.  IL-4 and many roads to lupuslike autoimmunity. , 2003, Clinical immunology.

[14]  Jonathan A. Bernstein,et al.  V75R576 IL-4 Receptor α Is Associated with Allergic Asthma and Enhanced IL-4 Receptor Function1 , 2002, The Journal of Immunology.

[15]  J. Lindhe,et al.  The presence of local and circulating autoreactive B cells in patients with advanced periodontitis. , 2002, Journal of clinical periodontology.

[16]  D. Metcalfe,et al.  Association of the Q576R polymorphism in the interleukin-4 receptor alpha chain with indolent mastocytosis limited to the skin. , 2001, Blood.

[17]  J. C. Pratt,et al.  A Murine IL-4 Receptor Antagonist That Inhibits IL-4- and IL-13-Induced Responses Prevents Antigen-Induced Airway Eosinophilia and Airway Hyperresponsiveness1 , 2001, The Journal of Immunology.

[18]  J. Meyle,et al.  Interleukin-4 polymorphisms in early onset periodontitis. , 2001, Journal of clinical periodontology.

[19]  F. Weber,et al.  Analysis of interleukin-4 receptor α chain variants in multiple sclerosis , 2001, Journal of Neuroimmunology.

[20]  J C Gunsolley,et al.  Evidence of a substantial genetic basis for risk of adult periodontitis. , 2000, Journal of periodontology.

[21]  S. Socransky,et al.  Microbiological parameters associated with IL-1 gene polymorphisms in periodontitis patients. , 2000, Journal of clinical periodontology.

[22]  S. Hwang,et al.  Association of the interleukin-4 receptor α variant Q576R with Th1/Th2 imbalance in connective tissue disease , 2000, Immunogenetics.

[23]  M. Marinaro,et al.  IL-4 Promotes the Migration of Circulating B Cells to the Spleen and Increases Splenic B Cell Survival1 , 2000, The Journal of Immunology.

[24]  G. Armitage,et al.  Development of a classification system for periodontal diseases and conditions. , 1999, Annals of periodontology.

[25]  H. Hackstein,et al.  The IL-4 receptor alpha-chain variant Q576R is strongly associated with decreased kidney allograft survival. , 1999, Tissue antigens.

[26]  H. Hackstein,et al.  Definition of human interleukin-4 receptor alpha chain haplotypes and allelic association with atopy markers. , 1999, Human immunology.

[27]  J. Bernstein,et al.  The R576 IL-4 receptor α allele correlates with asthma severity☆☆☆★ , 1999 .

[28]  C. Meduri,et al.  Effects of Cytokines and Endotoxin on the Intracellular Growth of Bacteria , 1999, Infection and Immunity.

[29]  I. Lamster,et al.  The Influence of Interleukin Gene Polymorphism on Expression of Interleukin-1β and Tumor Necrosis Factor-α in Periodontal Tissue and Gingival Crevicular Fluid. , 1999, Journal of periodontology.

[30]  Sparholt,et al.  The polymorphisms S503P and Q576R in the interleukin‐4 receptor α gene are associated with atopy and influence the signal transduction , 1999, Immunology.

[31]  R. Puri,et al.  Interleukin-13 Receptor α′ But Not α Chain: A Functional Component of Interleukin-4 Receptors , 1998 .

[32]  J. Banchereau,et al.  An update on interleukin-4 and its receptor. , 1997, European cytokine network.

[33]  T. Chatila,et al.  The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor. , 1997, The New England journal of medicine.

[34]  S. Akira,et al.  STAT6: its role in interleukin 4-mediated biological functions , 1997, Journal of Molecular Medicine.

[35]  R. Puri,et al.  cDNA Cloning and Characterization of the Human Interleukin 13 Receptor α Chain* , 1996, The Journal of Biological Chemistry.

[36]  J. G. Zhang,et al.  Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[37]  J. Banchereau,et al.  The Primary Binding Subunit of the Human Interleukin-4 Receptor Is Also a Component of the Interleukin-13 Receptor (*) , 1995, The Journal of Biological Chemistry.

[38]  K. Arai,et al.  Involvement of the interleukin‐2 receptor γ subunit in interleukin‐4‐dependent activation of mouse hematopoietic cells and splenic B cells , 1995, European journal of immunology.

[39]  Y. Yang,et al.  JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes. , 1994, The Journal of biological chemistry.

[40]  G. Seymour,et al.  IL-4- and IL-6-producing cells in human periodontal disease tissue. , 1994, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[41]  M. Marazita,et al.  Evidence for autosomal dominant inheritance and race-specific heterogeneity in early-onset periodontitis. , 1994, Journal of periodontology.

[42]  S. Socransky,et al.  Microbial etiological agents of destructive periodontal diseases. , 1994, Periodontology 2000.

[43]  W. Paul,et al.  Lymphocyte responses and cytokines , 1994, Cell.

[44]  G. Seymour,et al.  Immunopathogenesis of chronic inflammatory periodontal disease: cellular and molecular mechanisms. , 1993, Journal of periodontal research.

[45]  R. Ashman,et al.  Apoptosis in splenic B lymphocytes. Regulation by protein kinase C and IL-4. , 1993, Journal of immunology.

[46]  L. Shapira,et al.  A localized absence of interleukin-4 triggers periodontal disease activity: a novel hypothesis. , 1992, Medical hypotheses.

[47]  F. Pociot,et al.  A Taql polymorphism in the human interleukin‐1β (IL‐1β) gene correlates with IL‐1β secretion in vitro , 1992 .

[48]  C. Dinarello,et al.  Enhancement of growth of virulent strains of Escherichia coli by interleukin-1. , 1991, Science.

[49]  N. Copeland,et al.  The interleukin-4 receptor gene (IL4R) maps to 16p11.2-16p12.1 in human and to the distal region of mouse chromosome 7. , 1991, Genomics.

[50]  W. Paul Interleukin-4: a prototypic immunoregulatory lymphokine. , 1991, Blood.

[51]  J. Banchereau,et al.  Molecular cloning of a cDNA encoding the human interleukin 4 receptor. , 1990, International immunology.

[52]  C. March,et al.  Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily , 1990, The Journal of experimental medicine.

[53]  F. Abbas,et al.  Prevalence of periodontal breakdown in adolescents and presence of Actinobacillus actinomycetemcomitans in subjects with attachment loss. , 1989, Journal of periodontology.

[54]  D. Kinane,et al.  The 'high risk' group in periodontitis , 1989, British Dental Journal.

[55]  H. Mühlemann,et al.  Gingival sulcus bleeding--a leading symptom in initial gingivitis. , 1971, Helvetica odontologica acta.

[56]  R. Bödeker,et al.  The interleukin-4 -34TT and -590TT genotype is correlated with increased expression and protein production in aggressive periodontitis. , 2010, Molecular immunology.

[57]  D. Lange,et al.  [Clinical methods for the objective evaluation of oral hygiene]. , 1977, Deutsche zahnarztliche Zeitschrift.