Topical ophthalmic use of cyclosporin A for Splendore‐Hoeppli phenomenon

The Splendore‐Hoeppli reaction is a rare phenomenon characterised by the formation of eosinophilic material around infectious or non‐infectious agents. A 33‐year‐old patient with persistent Splendore‐Hoeppli phenomenon was previously treated with topical steroids but this resulted in a rise in intraocular pressure. The patient was treated with topical cyclosporin A one per cent twice daily as an alternative immunosuppression. After three weeks of treatment the patient had complete resolution of her conjunctival granuloma. This case report introduces cyclosporin A as a treatment option for the Splendore‐Hoeppli phenomenon. This is a safe drug for long‐term topical use in this condition.