mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia

[1]  W. Spooren,et al.  Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic pain , 2001, Neuropharmacology.

[2]  G. Seabrook,et al.  Mobilisation of intracellular Ca2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones , 2000, Neuropharmacology.

[3]  D. Jane,et al.  Pharmacological agents acting at subtypes of metabotropic glutamate receptors , 1999, Neuropharmacology.

[4]  Roland Heckendorn,et al.  2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist , 1999, Neuropharmacology.

[5]  J. Valtschanoff,et al.  Metabotropic glutamate receptors in superficial laminae of the rat dorsal horn , 1999, The Journal of comparative neurology.

[6]  F. Gasparini,et al.  Antagonism of the mGlu5 agonist 2‐chloro‐5‐hydroxyphenylglycine by the novel selective mGlu5 antagonist 6‐methyl‐2‐(phenylethynyl)‐pyridine (MPEP) in the thalamus , 1999, British journal of pharmacology.

[7]  W. Willis,et al.  Role of metabotropic glutamate receptor subtype mGluR1 in brief nociception and central sensitization of primate STT cells. , 1999, Journal of neurophysiology.

[8]  Y. Smith,et al.  Activation of N‐Methyl‐D‐Aspartate Receptors Reverses Desensitization of Metabotropic Glutamate Receptor, mGluR5, in Native and Recombinant Systems , 1999, Annals of the New York Academy of Sciences.

[9]  S. Heinemann,et al.  Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems , 1999, Nature Neuroscience.

[10]  W. Zieglgänsberger,et al.  Distribution and developmental changes in metabotropic glutamate receptor messenger RNA expression in the rat lumbar spinal cord. , 1999, Brain research. Developmental brain research.

[11]  M. J. Johnson,et al.  Antisense Ablation of Type I Metabotropic Glutamate Receptor mGluR1 Inhibits Spinal Nociceptive Transmission , 1998, The Journal of Neuroscience.

[12]  T. Brennan,et al.  Intrathecal Metabotropic Glutamate Receptor Antagonists Do Not Decrease Mechanical Hyperalgesia in a Rat Model of Postoperative Pain , 1998, Anesthesia and analgesia.

[13]  A. Basbaum,et al.  The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli , 1998, Neuron.

[14]  Louise C. Stanfa,et al.  Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. , 1998, European journal of pharmacology.

[15]  T. Salt,et al.  Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine , 1998, Neuroscience.

[16]  T. Coderre,et al.  Hyperalgesia and allodynia induced by intrathecal (RS)‐dihydroxyphenylglycine in rats , 1998, Neuroreport.

[17]  W. Zieglgänsberger,et al.  mGluR activation reveals a tonic NMDA component in inflammatory hyperalgesia , 1998, Neuroreport.

[18]  K. Omote,et al.  Formalin-induced release of excitatory amino acids in the skin of the rat hindpaw , 1998, Brain Research.

[19]  G. Guilbaud,et al.  The enhancement of morphine antinociception by a CCKB receptor antagonist in the rat depends on the phase of inflammation and the intensity of carrageenin-induced hyperalgesia , 1998, Pain.

[20]  D. Laurie,et al.  Enhanced expression of metabotropic glutamate receptor 3 messenger RNA in the rat spinal cord during ultraviolet irradiation induced peripheral inflammation , 1997, Neuroscience.

[21]  M. Memo,et al.  mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study , 1997, Neuroscience Research.

[22]  W. Willis,et al.  Excitatory amino acid receptor involvement in peripheral nociceptive transmission in rats. , 1997, European journal of pharmacology.

[23]  S. Wakisaka,et al.  Regeneration of periodontal primary afferents of the rat incisor following injury of the inferior alveolar nerve with special reference to neuropeptide Y-like immunoreactive primary afferents , 1997, Brain Research.

[24]  R. Coggeshall,et al.  Peripheral NMDA and non‐NMDA glutamate receptors contribute to nociceptive behaviors in the rat formalin test , 1997, Neuroreport.

[25]  D. Schoepp,et al.  Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties. , 1997, Journal of medicinal chemistry.

[26]  T. Coderre,et al.  The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception , 1996, Pain.

[27]  T. Coderre,et al.  Comparison of nociceptive effects produced by intrathecal administration of mGluR agonists. , 1996, Neuroreport.

[28]  S. Carlton,et al.  Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats , 1996, Neuroreport.

[29]  A. Dray,et al.  Development of hyperthermia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists , 1996, British journal of pharmacology.

[30]  J. D. Richardson,et al.  Glutamate participates in the peripheral modulation of thermal hyperalgesia in rats. , 1995, European journal of pharmacology.

[31]  R. Coggeshall,et al.  Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin , 1995, Neuroscience Letters.

[32]  J. Bockaert,et al.  Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses , 1995, Neuropharmacology.

[33]  D. Lodge,et al.  Pharmacology of metabotropic glutamate receptor-mediated enhancement of responses to excitatory and inhibitory amino acids on rat spinal neurones in vivo , 1995, Neuropharmacology.

[34]  D. Lodge,et al.  Pharmacological analysis of 4-carboxyphenylglycine derivatives: Comparison of effects on mGluR1α and mGluR5a subtypes , 1995, Neuropharmacology.

[35]  A. N. van den Pol,et al.  Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain , 1995, The Journal of comparative neurology.

[36]  T. Knöpfel,et al.  Metabotropic glutamate receptors: novel targets for drug development. , 1995, Journal of medicinal chemistry.

[37]  Shigetada Nakanishi,et al.  Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain , 1993, Neuroscience Letters.

[38]  A. Herz,et al.  Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: Alterations in behavior and nociceptive thresholds , 1988, Pharmacology Biochemistry and Behavior.

[39]  A. Dickenson,et al.  Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following c fibre stimulation. , 1987, Neuropharmacology.

[40]  T. Salt,et al.  Mediation of thalamic sensory input by both NMDA receptors and non-NMDA receptors , 1986, Nature.

[41]  G. Wilcox,et al.  Intrathecal morphine in mice: a new technique. , 1980, European journal of pharmacology.

[42]  B. Cairns,et al.  Development of inflammation after application of mustard oil or glutamate to the rat temporomandibular joint. , 1999, Archives of oral biology.

[43]  J. Pin,et al.  Pharmacology and functions of metabotropic glutamate receptors. , 1997, Annual review of pharmacology and toxicology.

[44]  W. Willis.  Hyperalgesia and allodynia , 1992 .