Non-contact acoustic trapping in circular cross-section glass capillaries: a numerical study.

Ultrasonic particle manipulation has many applications in microfluidic systems. Such manipulation is achievable by establishing an ultrasonic standing wave in fluid filled micromachined chambers. In this work, the focus is on analyzing the trapping potential of water filled capillary tubes actuated ultrasonically. The curved walls necessitate the use of a finite element modeling approach. Multiple arrangements of the piezoelectric transducers were studied along with the effects of changing the capillary and piezoelectric transducer thicknesses. Additionally, different modes of driving the piezoelectric transducers were investigated. It was found that positioning four piezoelectric transducers equally spaced around the capillary tube provided the best force potential field for trapping polystyrene spheres in the center of the capillary.

[1]  T. Ng,et al.  Brownian rod scheme in microenvironment sensing , 2012 .

[2]  G. Silva.  An expression for the radiation force exerted by an acoustic beam with arbitrary wavefront (L). , 2011, The Journal of the Acoustical Society of America.

[3]  Adrian Neild,et al.  Selective particle trapping using an oscillating microbubble. , 2011, Lab on a chip.

[4]  A. Neild,et al.  Towards the automation of micron-sized particle handling by use of acoustic manipulation assisted by microfluidics. , 2008, Ultrasonics.

[5]  Martyn Hill,et al.  Modelling for the robust design of layered resonators for ultrasonic particle manipulation. , 2008, Ultrasonics.

[6]  H. Hertz,et al.  Wedge transducer design for two-dimensional ultrasonic manipulation in a microfluidic chip , 2008 .

[7]  Hans M. Hertz,et al.  A three-dimensional ultrasonic cage for characterization of individual cells , 2008 .

[8]  Adrian Neild,et al.  Simultaneous positioning of cells into two-dimensional arrays using ultrasound. , 2007, Biotechnology and bioengineering.

[9]  S M Hagsäter,et al.  Acoustic resonances in microfluidic chips: full-image micro-PIV experiments and numerical simulations. , 2007, Lab on a chip.

[10]  Adrian Neild,et al.  Design, modeling and characterization of microfluidic devices for ultrasonic manipulation , 2007 .

[11]  B. Nelson,et al.  Monolithically Fabricated Microgripper With Integrated Force Sensor for Manipulating Microobjects and Biological Cells Aligned in an Ultrasonic Field , 2007, Journal of Microelectromechanical Systems.

[12]  Adrian Neild,et al.  Manipulation of micrometer sized particles within a micromachined fluidic device to form two-dimensional patterns using ultrasound. , 2007, The Journal of the Acoustical Society of America.

[13]  A. Neild,et al.  Finite element modeling of a microparticle manipulator. , 2006, Ultrasonics.

[14]  Achim Wixforth,et al.  Acoustic mixing at low Reynold's numbers , 2006 .

[15]  T. Laurell,et al.  Continuous separation of lipid particles from erythrocytes by means of laminar flow and acoustic standing wave forces. , 2005, Lab on a chip.

[16]  David A. Hutchins,et al.  A model for the radiated field of a plane piston after reflection from a curved surface , 2004 .

[17]  Theodore C Marentis,et al.  Ultrasonic mixing in microfluidic channels using integrated transducers. , 2004, Analytical chemistry.

[18]  A. Manz,et al.  Micro total analysis systems. Recent developments. , 2004, Analytical chemistry.

[19]  Jeremy J Hawkes,et al.  Ultrasonic deposition of cells on a surface. , 2004, Biosensors & bioelectronics.

[20]  D. Erickson,et al.  Integrated microfluidic devices , 2004 .

[21]  Martyn Hill,et al.  The selection of layer thicknesses to control acoustic radiation force profiles in layered resonators. , 2003, The Journal of the Acoustical Society of America.

[22]  Gregory Goddard,et al.  Ultrasonic particle concentration in a line-driven cylindrical tube. , 2003, The Journal of the Acoustical Society of America.

[23]  A. Pisano,et al.  Ultrasonic particle manipulation in microchannels using phased co-planar transducers , 2003, TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664).

[24]  P. Marmottant,et al.  Controlled vesicle deformation and lysis by single oscillating bubbles , 2003, Nature.

[25]  Martyn Hill,et al.  Modelling of layered resonators for ultrasonic separation. , 2002, Ultrasonics.

[26]  David A. Hutchins,et al.  Surface metrology using reflected ultrasonic signals in air , 2002 .

[27]  M. Groschl,et al.  Ultrasonic separation of suspended particles , 2001, 2001 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.01CH37263).

[28]  Hans M. Hertz,et al.  Ultrasonic trapping in capillaries for trace-amount biomedical analysis , 2001 .

[29]  Jeremy J. Hawkes,et al.  Force field particle filter, combining ultrasound standing waves and laminar flow , 2001 .

[30]  Hill,et al.  Modelling in the design of a flow-through ultrasonic separator , 2000, Ultrasonics.

[31]  K. Shuster,et al.  The effect of centreline particle concentration in a wave tube , 1996, Journal of Fluid Mechanics.

[32]  Hans M. Hertz,et al.  Standing-wave Acoustic Trap For Nonintrusive Positioning of Microparticles , 1995 .

[33]  S. Chu,et al.  Observation of a single-beam gradient force optical trap for dielectric particles. , 1986, Optics letters.

[34]  D. Kerrisk,et al.  Containerless processing technologies at the Jet Propulsion Laboratory , 1984 .

[35]  Mark C. Lee,et al.  Acoustic levitating apparatus for submillimeter samples , 1982 .

[36]  W. Coakley,et al.  Bacterial spore capture on an immunosensor surface in a BAW resonator , 2004, Proceedings of IEEE Sensors, 2004..

[37]  M. Wiklunda,et al.  Ultrasonic trapping in capillaries for trace-amount biomedical analysis , 2001 .

[38]  N. Riley.  Acoustic Streaming , 1998 .

[39]  Wesley Le Mars Nyborg,et al.  11 - Acoustic Streaming , 1965 .

[40]  K. Yosioka,et al.  Acoustic radiation pressure on a compressible sphere , 1955 .

[41]  Lawrence E. Kinsler,et al.  Fundamentals of acoustics , 1950 .