Interactions between stem cell factor and c-Kit are required for intestinal immune system homeostasis.

[1]  L. Lefrançois,et al.  A novel pathway of thymus-directed T lymphocyte maturation. , 1994, Journal of immunology.

[2]  A. Zlotnik,et al.  Control points in early T-cell development. , 1993, Immunology today.

[3]  G. Matsuzaki,et al.  Thymus influences the development of extrathymically derived intestinal intraepithelial lymphocytes , 1993, European journal of immunology.

[4]  R. de Waal Malefyt,et al.  Untransfected and SV40-transfected fetal and postnatal human thymic stromal cells. Analysis of phenotype, cytokine gene expression and cytokine production. , 1993, Thymus.

[5]  S. Wolf,et al.  Expression of cytokines and their receptors by human thymocytes and thymic stromal cells. , 1992, Immunology.

[6]  S. Nishikawa,et al.  Requirement of c-kit for development of intestinal pacemaker system. , 1992, Development.

[7]  A. Zlotnik,et al.  Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. , 1992, Journal of immunology.

[8]  M. Binnie,et al.  Thymus-independent development and negative selection of T cells expressing T cell receptor alpha/beta in the intestinal epithelium: evidence for distinct circulation patterns of gut- and thymus-derived T lymphocytes , 1992, The Journal of experimental medicine.

[9]  D. Williams,et al.  The Steel factor. , 1992, Developmental biology.

[10]  P. Vassalli,et al.  Different expression of the recombination activity gene RAG‐1 in various populations of thymocytes, peripheral T cells and gut thymus‐independent intraepithelial lymphocytes suggests two pathways of T cell receptor rearrangement , 1992, European journal of immunology.

[11]  G. Evans,et al.  A low-temperature method for the isolation of small-intestinal epithelium along the crypt-villus axis. , 1991, The Biochemical journal.

[12]  L. Lefrançois,et al.  Phenotypic complexity of intraepithelial lymphocytes of the small intestine. , 1991, Journal of immunology.

[13]  D. Williams,et al.  Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[14]  D. Harrison,et al.  Lymphoid and erythroid repopulation in B6 W-anemic mice: a new unirradiated recipient. , 1991, Experimental hematology.

[15]  P. Leder,et al.  Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant , 1991, Cell.

[16]  B. Rocha,et al.  The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation , 1991, The Journal of experimental medicine.

[17]  B. Malissen,et al.  Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation , 1991, The Journal of experimental medicine.

[18]  J. Bluestone,et al.  Extrathymic selection of TCR γδ + T cells by class II major histocompatibility complex molecules , 1990, Cell.

[19]  P. Leder,et al.  The kit ligand: A cell surface molecule altered in steel mutant fibroblasts , 1990, Cell.

[20]  David A. Williams,et al.  Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor , 1990, Cell.

[21]  P. Leder,et al.  The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus , 1990, Cell.

[22]  C. March,et al.  Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms , 1990, Cell.

[23]  N. Copeland,et al.  Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles , 1990, Cell.

[24]  R. Mosley,et al.  Differentiation and functional maturation of bone marrow-derived intestinal epithelial T cells expressing membrane T cell receptor in athymic radiation chimeras. , 1990, Journal of immunology.

[25]  N. Brousse,et al.  Subsets of CD3+ (T cell receptor α/β or γ/δ) and CD3− lymphocytes isolated from normal human gut epithelium display phenotypical features different from their counterparts in peripheral blood , 1990 .

[26]  R. Mosley,et al.  CD4+CD8+ murine intestinal intraepithelial lymphocytes. , 1990, International immunology.

[27]  J. Allison,et al.  Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors , 1990, Nature.

[28]  A. Reith,et al.  W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor. , 1990, Genes & development.

[29]  B. de Geus,et al.  Phenotype of intraepithelial lymphocytes in euthymic and athymic mice: Implications for differentiation of cells bearing a CD3‐associated γδ T cell receptor , 1990 .

[30]  L. Lefrançois,et al.  Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function , 1989, The Journal of experimental medicine.

[31]  A. Bernstein,et al.  Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice. , 1989, Genes & development.

[32]  J. Allison,et al.  Limited diversity of T-cell receptor gamma-chain expression of murine Thy-1+ dendritic epidermal cells revealed by V gamma 3-specific monoclonal antibody. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[33]  P. Marrack,et al.  Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. , 1989, Journal of immunology.

[34]  D. Housman,et al.  The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene , 1988, Cell.

[35]  V. Chapman,et al.  The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus , 1988, Nature.

[36]  L. Lefrançois,et al.  Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes , 1988, Nature.

[37]  F. Ruddle,et al.  Primary structure of c‐kit: relationship with the CSF‐1/PDGF receptor kinase family–oncogenic activation of v‐kit involves deletion of extracellular domain and C terminus. , 1988, The EMBO journal.

[38]  J. Bluestone,et al.  Identification of a monoclonal antibody specific for a murine T3 polypeptide. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[39]  J. Streilein,et al.  FACS purification of bone marrow-derived epidermal populations in mice: Langerhans cells and Thy-1+ dendritic cells. , 1985, The Journal of investigative dermatology.

[40]  J. Lowenthal,et al.  Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells , 1985, Nature.

[41]  G. Church,et al.  Genomic sequencing. , 1993, Methods in molecular biology.

[42]  J. Sprent,et al.  A monoclonal antibody discriminating between subsets of T and B cells. , 1981, Journal of immunology.

[43]  A. Glasebrook,et al.  IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. , 1980, Journal of immunology.

[44]  S. Tonegawa,et al.  Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[45]  P. Bergstresser,et al.  Detection by immunochemical techniques of cell surface markers on epidermal Langerhans cells. , 1984, Methods in enzymology.

[46]  E. Russell.  Hereditary anemias of the mouse: a review for geneticists. , 1979, Advances in genetics.