Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice

[1]  I. Ferrer,et al.  αB‐crystallin and HSP27 in glial cells in tauopathies , 2014, Neuropathology : official journal of the Japanese Society of Neuropathology.

[2]  T. Bredy,et al.  Activation‐induced cytidine deaminase regulates activity‐dependent BDNF expression in post‐mitotic cortical neurons , 2014, The European journal of neuroscience.

[3]  J. Kleinman,et al.  Increased expression of MARCKS in post-mortem brain of violent suicide completers is related to transcription of a long, noncoding, antisense RNA , 2014, Molecular Psychiatry.

[4]  Patrick R Hof,et al.  Developmental changes in the transcriptome of human cerebral cortex tissue: long noncoding RNA transcripts. , 2014, Cerebral cortex.

[5]  Yong-Bin Yan,et al.  The N-terminal extension of βB1-crystallin chaperones β-crystallin folding and cooperates with αA-crystallin. , 2014, Biochemistry.

[6]  J. Mattick,et al.  The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing , 2014, Molecular Psychiatry.

[7]  J. Ravanat,et al.  DNA binding of the p21 repressor ZBTB2 is inhibited by cytosine hydroxymethylation. , 2014, Biochemical and biophysical research communications.

[8]  Adrian G. Palacios,et al.  Alzheimer's disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers , 2014, Alzheimer's & Dementia.

[9]  H. Deng,et al.  Molecular genetics of congenital nuclear cataract. , 2014, European journal of medical genetics.

[10]  J. Medina,et al.  BDNF and memory processing , 2014, Neuropharmacology.

[11]  S. Siris,et al.  Anxiety comorbidity in schizophrenia , 2013, Psychiatry Research.

[12]  J. Rinn,et al.  Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2 , 2013, Genome Biology.

[13]  Hongbo Liu,et al.  Long non-coding RNA identification over mouse brain development by integrative modeling of chromatin and genomic features , 2013, Nucleic acids research.

[14]  C. Wahlestedt,et al.  Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome , 2013, Human Genetics.

[15]  J. F. Maya-Vetencourt Activity-Dependent NPAS4 Expression and the Regulation of Gene Programs Underlying Plasticity in the Central Nervous System , 2013, Neural plasticity.

[16]  L. Stanton,et al.  The long noncoding RNA RMST interacts with SOX2 to regulate neurogenesis. , 2013, Molecular cell.

[17]  H. Ding,et al.  Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation , 2013, Oncogene.

[18]  J. Mattick,et al.  Understanding the regulatory and transcriptional complexity of the genome through structure , 2013, Genome research.

[19]  Shane J. Neph,et al.  DNase I–hypersensitive exons colocalize with promoters and distal regulatory elements , 2013, Nature Genetics.

[20]  M. Serresi,et al.  In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis. , 2013, Cancer cell.

[21]  M. Esteller,et al.  Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model , 2013, RNA biology.

[22]  G. Grassi,et al.  Anxiety as a Core Aspect of Schizophrenia , 2013, Current Psychiatry Reports.

[23]  J. Mattick,et al.  Structure and function of long noncoding RNAs in epigenetic regulation , 2013, Nature Structural &Molecular Biology.

[24]  M. Gorospe,et al.  Long Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYB , 2013, PLoS genetics.

[25]  Yoko Furukawa-Hibi,et al.  Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist‐bound glucocorticoid receptor to its promoter , 2012, Journal of neurochemistry.

[26]  G. Wistow The human crystallin gene families , 2012, Human Genomics.

[27]  Yan Li,et al.  Transcriptome analysis of long non‐coding RNAs of the nucleus accumbens in cocaine‐conditioned mice , 2012, Journal of neurochemistry.

[28]  L. Lipovich,et al.  Activity-Dependent Human Brain Coding/Noncoding Gene Regulatory Networks , 2012, Genetics.

[29]  M. Ziats,et al.  Aberrant Expression of Long Noncoding RNAs in Autistic Brain , 2012, Journal of Molecular Neuroscience.

[30]  J. Davie,et al.  Pre-mRNA splicing: role of epigenetics and implications in disease. , 2012, Advances in biological regulation.

[31]  Danielle L. Pfaff,et al.  Anxiety Disorder Comorbidity in Bipolar Disorder, Schizophrenia and Schizoaffective Disorder , 2012, Psychopathology.

[32]  Stephen Maren,et al.  Neural and cellular mechanisms of fear and extinction memory formation , 2012, Neuroscience & Biobehavioral Reviews.

[33]  Chaolin Zhang,et al.  The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult. , 2012, Cell reports.

[34]  K. Lesch,et al.  Epigenetic regulation of the BDNF gene: implications for psychiatric disorders , 2012, Molecular Psychiatry.

[35]  A. Iwama,et al.  Bmi1 Confers Resistance to Oxidative Stress on Hematopoietic Stem Cells , 2012, PloS one.

[36]  K. Mirnics,et al.  Effects of maternal immune activation on gene expression patterns in the fetal brain , 2012, Translational Psychiatry.

[37]  Weidong Tian,et al.  Epigenetic features are significantly associated with alternative splicing , 2012, BMC Genomics.

[38]  Zhen Yan,et al.  Repeated Stress Causes Cognitive Impairment by Suppressing Glutamate Receptor Expression and Function in Prefrontal Cortex , 2012, Neuron.

[39]  David R. Kelley,et al.  Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks , 2012, Nature Protocols.

[40]  G. Bernier,et al.  Bmi1 Is Down-Regulated in the Aging Brain and Displays Antioxidant and Protective Activities in Neurons , 2012, PloS one.

[41]  Rory Johnson,et al.  Human long non‐coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors , 2012, The EMBO journal.

[42]  Hui Xiao,et al.  NONCODE v3.0: integrative annotation of long noncoding RNAs , 2011, Nucleic Acids Res..

[43]  Cole Trapnell,et al.  Targeted RNA sequencing reveals the deep complexity of the human transcriptome , 2011, Nature Biotechnology.

[44]  B. Schreurs,et al.  Incubation of conditioning-specific reflex modification: implications for Post Traumatic Stress Disorder. , 2011, Journal of psychiatric research.

[45]  J. Rinn,et al.  Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. , 2011, Genes & development.

[46]  D. Zheng,et al.  RNA-Seq of Human Neurons Derived from iPS Cells Reveals Candidate Long Non-Coding RNAs Involved in Neurogenesis and Neuropsychiatric Disorders , 2011, PloS one.

[47]  G. Schafe,et al.  The Neuronal PAS Domain Protein 4 (Npas4) Is Required for New and Reactivated Fear Memories , 2011, PloS one.

[48]  A. Achim,et al.  How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association. , 2011, Schizophrenia bulletin.

[49]  A. Arnsten Prefrontal cortical network connections: key site of vulnerability in stress and schizophrenia , 2011, International Journal of Developmental Neuroscience.

[50]  Iole Indovina,et al.  Fear-Conditioning Mechanisms Associated with Trait Vulnerability to Anxiety in Humans , 2011, Neuron.

[51]  G. Rebec,et al.  Chronic stress alters neural activity in medial prefrontal cortex during retrieval of extinction , 2011, Neuroscience.

[52]  Leonard Lipovich,et al.  Mining Affymetrix microarray data for long non‐coding RNAs: altered expression in the nucleus accumbens of heroin abusers , 2011, Journal of neurochemistry.

[53]  R. F. Luco,et al.  Epigenetics in Alternative Pre-mRNA Splicing , 2011, Cell.

[54]  John S. Mattick,et al.  lncRNAdb: a reference database for long noncoding RNAs , 2010, Nucleic Acids Res..

[55]  A. Liou,et al.  Heat shock proteins: Cellular and molecular mechanisms in the central nervous system , 2010, Progress in Neurobiology.

[56]  B. Blencowe,et al.  The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. , 2010, Molecular cell.

[57]  Michael Q. Zhang,et al.  A long nuclear‐retained non‐coding RNA regulates synaptogenesis by modulating gene expression , 2010, The EMBO journal.

[58]  T. Nabeshima,et al.  Chronic restraint stress impairs neurogenesis and hippocampus‐dependent fear memory in mice: possible involvement of a brain‐specific transcription factor Npas4 , 2010, Journal of neurochemistry.

[59]  Howard Y. Chang,et al.  Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes , 2010, Science.

[60]  C. Ponting,et al.  Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes , 2010, Genome Biology.

[61]  Xin-Yao Yu,et al.  Identification and Characterization of Bmi-1-responding Element within the Human p16 Promoter* , 2010, The Journal of Biological Chemistry.

[62]  S. Raguz,et al.  Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. , 2010, Molecular cell.

[63]  G. Kreiman,et al.  Widespread transcription at neuronal activity-regulated enhancers , 2010, Nature.

[64]  J. Rinn,et al.  RNA traffic control of chromatin complexes. , 2010, Current opinion in genetics & development.

[65]  J. Mattick,et al.  Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation , 2010, BMC Neuroscience.

[66]  S. Rauch,et al.  Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder , 2009, Biological Psychiatry.

[67]  C. Peterson,et al.  Chromatin immunoprecipitation (ChIP). , 2009, Cold Spring Harbor protocols.

[68]  Yingying Lian,et al.  Role of human noncoding RNAs in the control of tumorigenesis , 2009, Proceedings of the National Academy of Sciences.

[69]  C. Ponting,et al.  Genomic and Transcriptional Co-Localization of Protein-Coding and Long Non-Coding RNA Pairs in the Developing Brain , 2009, PLoS genetics.

[70]  S. Cheung,et al.  A 1q42 deletion involving DISC1, DISC2, and TSNAX in an autism spectrum disorder , 2009, American journal of medical genetics. Part A.

[71]  J. Rinn,et al.  Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression , 2009, Proceedings of the National Academy of Sciences.

[72]  E. Stone,et al.  Initiation codon mutation in βB1-crystallin (CRYBB1) associated with autosomal recessive nuclear pulverulent cataract , 2009, Molecular vision.

[73]  Linda Greensmith,et al.  Induction of heat shock proteins for protection against oxidative stress. , 2009, Advanced drug delivery reviews.

[74]  Dafydd G. Thomas,et al.  Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo. , 2009, Developmental biology.

[75]  J. Mattick The Genetic Signatures of Noncoding RNAs , 2009, PLoS genetics.

[76]  S. Salzberg,et al.  TopHat: discovering splice junctions with RNA-Seq , 2009, Bioinform..

[77]  John T. Dimos,et al.  Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. , 2009, Genes & development.

[78]  J. Mattick,et al.  Long non-coding RNAs: insights into functions , 2009, Nature Reviews Genetics.

[79]  C. Ponting,et al.  Evolution and Functions of Long Noncoding RNAs , 2009, Cell.

[80]  Michael F. Lin,et al.  Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals , 2009, Nature.

[81]  Marie-Pier Champagne,et al.  The Polycomb Group Gene Bmi1 Regulates Antioxidant Defenses in Neurons by Repressing p53 Pro-Oxidant Activity , 2009, The Journal of Neuroscience.

[82]  Paulo P. Amaral,et al.  RNA regulation of epigenetic processes , 2009, BioEssays : news and reviews in molecular, cellular and developmental biology.

[83]  Melike Nebioğlu,et al.  The prevalence of comorbid anxiety disorders in outpatients with schizophrenia , 2009, International journal of psychiatry in clinical practice.

[84]  E. Ullian,et al.  Neuronal pentraxins mediate silent synapse conversion in the developing visual system , 2008, International Journal of Developmental Neuroscience.

[85]  A. Ramos Animal models of anxiety: do I need multiple tests? , 2008, Trends in pharmacological sciences.

[86]  A. Arnsten,et al.  Molecular mechanisms of stress-induced prefrontal cortical impairment: implications for mental illness. , 2008, Learning & memory.

[87]  Paulo P. Amaral,et al.  The Eukaryotic Genome as an RNA Machine , 2008, Science.

[88]  S. Sunkin,et al.  Specific expression of long noncoding RNAs in the mouse brain , 2008, Proceedings of the National Academy of Sciences.

[89]  C. Wotjak,et al.  A mouse model of posttraumatic stress disorder that distinguishes between conditioned and sensitised fear. , 2007, Journal of psychiatric research.

[90]  T. Gilliam,et al.  Selection for contextual fear conditioning affects anxiety‐like behaviors and gene expression , 2007, Genes, brain, and behavior.

[91]  Michelle P. Salyers,et al.  Anxiety symptoms in schizophrenia spectrum disorders: associations with social function, positive and negative symptoms, hope and trauma history , 2007, Acta psychiatrica Scandinavica.

[92]  P. Calabresi,et al.  The Brain Cytoplasmic RNA BC1 Regulates Dopamine D2 Receptor-Mediated Transmission in the Striatum , 2007, The Journal of Neuroscience.

[93]  M. Takeichi,et al.  The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons , 2007, Journal of Cell Science.

[94]  J. Mattick,et al.  Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease. , 2007, Physiological reviews.

[95]  Howard Y. Chang,et al.  Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs , 2007, Cell.

[96]  John T. Dimos,et al.  shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. , 2007, Cell stem cell.

[97]  T. Bredy,et al.  Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. , 2007, Learning & memory.

[98]  Kristian Helin,et al.  The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. , 2007, Genes & development.

[99]  K. Davis,et al.  The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophrenia. , 2006, The American journal of psychiatry.

[100]  R. Greene,et al.  Postreactivation Glucocorticoids Impair Recall of Established Fear Memory , 2006, The Journal of Neuroscience.

[101]  N. Jareborg,et al.  Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[102]  C. Wellman,et al.  Chronic stress impairs recall of extinction of conditioned fear , 2006, Neurobiology of Learning and Memory.

[103]  U. Pettersson,et al.  Human QKI, a new candidate gene for schizophrenia involved in myelination , 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[104]  S. Batalov,et al.  Antisense Transcription in the Mammalian Transcriptome , 2005, Science.

[105]  S. Salzberg,et al.  The Transcriptional Landscape of the Mammalian Genome , 2005, Science.

[106]  S. Morrison,et al.  Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. , 2005, Genes & development.

[107]  G. Helt,et al.  Transcriptional Maps of 10 Human Chromosomes at 5-Nucleotide Resolution , 2005, Science.

[108]  C. Wotjak,et al.  Nonassociative learning processes determine expression and extinction of conditioned fear in mice. , 2004, Learning & memory.

[109]  J. Brosius,et al.  Role of a neuronal small non-messenger RNA: behavioural alterations in BC1 RNA-deleted mice , 2004, Behavioural Brain Research.

[110]  D. Stein,et al.  Anxiety disorders and schizophrenia , 2004, Current psychiatry reports.

[111]  J. Mattick RNA regulation: a new genetics? , 2004, Nature Reviews Genetics.

[112]  Masato Matsuura,et al.  Significant linkage to chromosome 22q for exploratory eye movement dysfunction in schizophrenia , 2003, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[113]  S. Morrison,et al.  Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation , 2003, Nature.

[114]  John Stewart,et al.  A genome-wide scan for linkage to chromosomal regions in 382 sibling pairs with schizophrenia or schizoaffective disorder. , 2002, The American journal of psychiatry.

[115]  J. Buccafusco Methods of Behavior Analysis in Neuroscience , 2000 .

[116]  Martin S. Taylor,et al.  Disruption of two novel genes by a translocation co-segregating with schizophrenia. , 2000, Human molecular genetics.

[117]  R. Murray,et al.  A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22). , 1996, American journal of medical genetics.

[118]  D. Housman,et al.  Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12-q13.1: Part 1. , 1994, American journal of medical genetics.

[119]  Jacqueline N. Crawley,et al.  Anxiety-Related Behaviors in Mice , 2009 .

[120]  J. Gorman,et al.  The Human Dimension: How the Prefrontal Cortex Modulates the Subcortical Fear Response , 2007, Reviews in the neurosciences.

[121]  HighWire Press The journal of neuroscience : the official journal of the Society for Neuroscience. , 1981 .