Zirconium ions integrated in 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) as a metalorganic-like complex coating on biodegradable magnesium for corrosion control

Abstract In this study, a coating of ionic Zr integrated in 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) metalorganic-like complexes was applied on Mg for corrosion control. HEDP was first immobilized on alkaline pretreated Mg followed by an alternating dip-coating process of Zr ions and HEDP to build a complex coating on Mg. This coating was demonstrated to be homogeneous, compact and with a metalorganic-like framework firmly anchored on Mg. This coating led to reduced corrosion current densities and remarkably suppressed long-term in vitro degradation of Mg in phosphate buffer saline (PBS). This complex coating showed promise for surface modification of Mg in biodegradable applications.

[1]  A R Boccaccini,et al.  Biomedical coatings on magnesium alloys - a review. , 2012, Acta biomaterialia.

[2]  X. Cui,et al.  Poly (3,4-ethylenedioxythiophene) graphene oxide composite coatings for controlling magnesium implant corrosion. , 2017, Acta biomaterialia.

[3]  K. Han,et al.  Conversion of glucose into levulinic acid with solid metal(IV) phosphate catalysts , 2013 .

[4]  G. Yuan,et al.  Facile Preparation of Poly(lactic acid)/Brushite Bilayer Coating on Biodegradable Magnesium Alloys with Multiple Functionalities for Orthopedic Application. , 2017, ACS applied materials & interfaces.

[5]  Yu-peng Lu,et al.  Phosphate chemical conversion coatings on metallic substrates for biomedical application: a review. , 2015, Materials science & engineering. C, Materials for biological applications.

[6]  C. Liang,et al.  Conversion coating treatment for AZ91 magnesium alloys by a permanganate‐REMS bath , 2007 .

[7]  S. Gnedenkov,et al.  Protective properties of inhibitor-containing composite coatings on a Mg alloy , 2016 .

[8]  Yufeng Zheng,et al.  Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats , 2016, Nature Medicine.

[9]  G. Yuan,et al.  The in vivo degradation and bone-implant interface of Mg-Nd-Zn-Zr alloy screws: 18 months post-operation results , 2016 .

[10]  M. Maitz,et al.  Sandwiched polydopamine (PDA) layer for titanium dioxide (TiO2) coating on magnesium to enhance corrosion protection , 2015 .

[11]  M. Maitz,et al.  Epigallocatechin gallate (EGCG) induced chemical conversion coatings for corrosion protection of biomedical MgZnMn alloys , 2015 .

[12]  B. Duan,et al.  A versatile dopamine-induced intermediate layer for polyether imides (PEI) deposition on magnesium to render robust and high inhibition performance , 2017 .

[13]  Frank Witte,et al.  Current status on clinical applications of magnesium-based orthopaedic implants: A review from clinical translational perspective. , 2017, Biomaterials.

[14]  E. Han,et al.  Corrosion resistance of a self-healing micro-arc oxidation/polymethyltrimethoxysilane composite coating on magnesium alloy AZ31 , 2017 .

[15]  Frank Witte,et al.  Reprint of: The history of biodegradable magnesium implants: A review. , 2015, Acta biomaterialia.

[16]  Di Ning,et al.  An Fe(II) metal–organic framework as a visible responsive photo-Fenton catalyst for the degradation of organophosphates , 2018 .

[17]  N. Huang,et al.  Controlling the corrosion rate and behavior of biodegradable magnesium by a surface-immobilized ultrathin 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) film , 2016 .

[18]  N Birbilis,et al.  Assessing the corrosion of biodegradable magnesium implants: a critical review of current methodologies and their limitations. , 2012, Acta biomaterialia.

[19]  N. Huang,et al.  Corrosion-controlling and osteo-compatible Mg ion-integrated phytic acid (Mg-PA) coating on magnesium substrate for biodegradable implants application. , 2014, ACS applied materials & interfaces.

[20]  D. Knight,et al.  Surface modification using phosphonic acids and esters. , 2012, Chemical reviews.

[21]  Yufeng Zheng,et al.  Magnesium alloy based interference screw developed for ACL reconstruction attenuates peri-tunnel bone loss in rabbits. , 2018, Biomaterials.

[22]  P. Chu,et al.  Surface design of biodegradable magnesium alloys — A review , 2013 .

[23]  M. Maitz,et al.  In situ incorporation of heparin/bivalirudin into a phytic acid coating on biodegradable magnesium with improved anticorrosion and biocompatible properties. , 2017, Journal of materials chemistry. B.

[24]  M. Maitz,et al.  Comparative corrosion behavior of Zn with Fe and Mg in the course of immersion degradation in phosphate buffered saline , 2016 .

[25]  F. Witte,et al.  Biodegradable Metals , 2018, Biomaterials Science.

[26]  T. narayanan,et al.  Strategies to improve the corrosion resistance of microarc oxidation (MAO) coated magnesium alloys for degradable implants: Prospects and challenges , 2014 .

[27]  G. Blanchard,et al.  Design and Demonstration of Hybrid Multilayer Structures: Layer-by-Layer Mixed Covalent and Ionic Interlayer Linking Chemistry , 2000 .

[28]  M. Easton,et al.  Controlling initial biodegradation of magnesium by a biocompatible strontium phosphate conversion coating. , 2014, Acta biomaterialia.

[29]  M. Sakamoto,et al.  Corrosion resistance and durability of superhydrophobic surface formed on magnesium alloy coated with nanostructured cerium oxide film and fluoroalkylsilane molecules in corrosive NaCl aqueous solution. , 2011, Langmuir : the ACS journal of surfaces and colloids.

[30]  Andrej Atrens,et al.  Measurement of the corrosion rate of magnesium alloys using Tafel extrapolation , 2010 .

[31]  Fu-hui Wang,et al.  Designing for the chemical conversion coating with high corrosion resistance and low electrical contact resistance on AZ91D magnesium alloy , 2018 .

[32]  Yufeng Zheng,et al.  In vitro and in vivo studies on the degradation of high-purity Mg (99.99wt.%) screw with femoral intracondylar fractured rabbit model. , 2015, Biomaterials.

[33]  G. Song,et al.  2-Hydroxy-4-methoxy-acetophenone as an environment-friendly corrosion inhibitor for AZ91D magnesium alloy , 2013 .

[34]  Chao-Sung Lin,et al.  Permanganate conversion coating on AZ31 magnesium alloys with enhanced corrosion resistance , 2015 .

[35]  S. Pourbeyram.  Effective Removal of Heavy Metals from Aqueous Solutions by Graphene Oxide–Zirconium Phosphate (GO–Zr-P) Nanocomposite , 2016 .

[36]  G. Grundmeier,et al.  Adsorption and stability of self-assembled organophosphonic acid monolayers on plasma modified Zn–Mg–Al alloy surfaces , 2013 .

[37]  Guang-Ling Song,et al.  Control of biodegradation of biocompatable magnesium alloys , 2007 .

[38]  D. Mckenzie,et al.  Effects of Zirconium and Oxygen Plasma Ion Implantation on the Corrosion Behavior of ZK60 Mg Alloy in Simulated Body Fluids , 2014 .

[39]  Yufeng Zheng,et al.  Corrosion resistance of dicalcium phosphate dihydrate/poly(lactic-co-glycolic acid) hybrid coating on AZ31 magnesium alloy , 2016 .

[40]  Prashant N. Kumta,et al.  In vivo study of magnesium plate and screw degradation and bone fracture healing. , 2015, Acta biomaterialia.

[41]  James F Curtin,et al.  Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications. , 2016, Materials science & engineering. C, Materials for biological applications.

[42]  N. Huang,et al.  Strengthened corrosion control of poly (lactic acid) (PLA) and poly (ε-caprolactone) (PCL) polymer-coated magnesium by imbedded hydrophobic stearic acid (SA) thin layer , 2016 .

[43]  Rongjun Qu,et al.  Biosorption of heavy metal ions onto agricultural residues buckwheat hulls functionalized with 1-hydroxylethylidenediphosphonic acid. , 2012, Journal of agricultural and food chemistry.

[44]  John R. Scully,et al.  Accurate Electrochemical Measurement of Magnesium Corrosion Rates; a Combined Impedance, Mass-Loss and Hydrogen Collection Study , 2014 .

[45]  Yang Ke,et al.  Surface Modification on Biodegradable Magnesium Alloys as Orthopedic Implant Materials to Improve the Bio-adaptability: A Review , 2016 .