A membrane-associated MHC-I inhibitory axis for cancer immune evasion
暂无分享,去创建一个
Hong Zhang | M. Pagano | P. Cresswell | Jia Liu | M. Cammer | Xufeng Chen | G. Róna | I. Aifantis | Audrey Lasry | B. Nadorp | Hua Zhou | Baoling Lai | Jun Wang | Debrup Sengupta | J. You | Kun Wang | Zhengxi Sun | Qiao Lu | Qianjin Guo | Jiangyan Zhang | P. Dahia | Wafa Al-Santli | Ahmad Boukhris | Zoe B. Ciantra | Cheng Liu
[1] J. Byrd,et al. An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia , 2022, Nature Cancer.
[2] Xiao-Dan Zhu,et al. Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression , 2022, Nature Communications.
[3] G. De Libero,et al. Mitochondrial Proteins as Source of Cancer Neoantigens , 2022, International journal of molecular sciences.
[4] M. Bhasin,et al. Survival Genie, a web platform for survival analysis across pediatric and adult cancers , 2021, Scientific Reports.
[5] T. Rodríguez,et al. MHC-I presents: tumor surveillance in the epithelia by cell competition , 2021, Nature Immunology.
[6] D. Dima,et al. Is There a Place for PD-1-PD-L Blockade in Acute Myeloid Leukemia? , 2021, Pharmaceuticals.
[7] K. Rock,et al. Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation , 2021, Frontiers in Immunology.
[8] C. Hammer,et al. Antigen presentation in cancer: insights into tumour immunogenicity and immune evasion , 2021, Nature Reviews Cancer.
[9] R. Tampé,et al. MHC I assembly and peptide editing - chaperones, clients, and molecular plasticity in immunity. , 2021, Current opinion in immunology.
[10] Clifford A. Meyer,et al. Therapeutically increasing MHC-I expression potentiates immune checkpoint blockade. , 2021, Cancer discovery.
[11] M. Raaben,et al. The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses. , 2021, Immunity.
[12] John G Doench,et al. In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma. , 2021, Immunity.
[13] Chunsheng Zhang,et al. STUB1 is an intracellular checkpoint for interferon gamma sensing , 2020, Scientific Reports.
[14] Jesse H. Arbuckle,et al. Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas. , 2020, Immunity.
[15] Chuan-Yuan Li,et al. PCSK9 inhibition potentiates cancer immune checkpoint therapy , 2020, Nature.
[16] J. Yewdell,et al. A few good peptides: MHC class I-based cancer immunosurveillance and immunoevasion , 2020, Nature Reviews Immunology.
[17] R. Aguiar,et al. Functional characterization of TMEM127 variants reveals novel insights into its membrane topology and trafficking. , 2020, The Journal of clinical endocrinology and metabolism.
[18] J. Pruneda,et al. The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules , 2020, Cell host & microbe.
[19] J. Debnath,et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I , 2020, Nature.
[20] Shixiang Wang,et al. Antigen presentation and tumor immunogenicity in cancer immunotherapy response prediction , 2019, eLife.
[21] E. Mardis. Neoantigens and genome instability: impact on immunogenomic phenotypes and immunotherapy response , 2019, Genome Medicine.
[22] R. Tothill,et al. An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer , 2019, Cancer cell.
[23] A. Brass,et al. Frequent Loss of IRF2 in Cancers Leads to Immune Evasion through Decreased MHC Class I Antigen Presentation and Increased PD-L1 Expression , 2019, The Journal of Immunology.
[24] T. Sakellaropoulos,et al. Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment. , 2019, Cancer discovery.
[25] Zemin Zhang,et al. GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis , 2019, Nucleic Acids Res..
[26] P. van Endert,et al. Endocytic Recycling of MHC Class I Molecules in Non-professional Antigen Presenting and Dendritic Cells , 2019, Front. Immunol..
[27] T. Schumacher,et al. Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers , 2018, Nature Medicine.
[28] Lieping Chen,et al. A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization , 2018, Cell.
[29] P. Cresswell,et al. A novel probe to assess cytosolic entry of exogenous proteins , 2018, Nature Communications.
[30] P. Cresswell,et al. Tumor-associated calreticulin variants functionally compromise the peptide loading complex and impair its recruitment of MHC-I , 2018, The Journal of Biological Chemistry.
[31] Guoping Cai,et al. Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer. , 2017, Cancer discovery.
[32] I. Melero,et al. Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy , 2017, Annals of oncology : official journal of the European Society for Medical Oncology.
[33] A. Sharpe,et al. The diverse functions of the PD1 inhibitory pathway , 2017, Nature Reviews Immunology.
[34] C. Foglieni,et al. Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins , 2017, Scientific Reports.
[35] R. Palmqvist,et al. TAP1 down-regulation elicits immune escape and poor prognosis in colorectal cancer , 2017, Oncoimmunology.
[36] T. Graeber,et al. Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations. , 2017, Cancer discovery.
[37] N. Sato,et al. Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition , 2017, Oncoimmunology.
[38] R. Yuan,et al. PD-1, PD-L1 (B7-H1) and Tumor-Site Immune Modulation Therapy: The Historical Perspective , 2017, Journal of Hematology & Oncology.
[39] S. Burrows,et al. CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold , 2016, Immunology and cell biology.
[40] V. Driss,et al. A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model , 2016, Journal of visualized experiments : JoVE.
[41] I. Cebrian,et al. Rab22a controls MHC‐I intracellular trafficking and antigen cross‐presentation by dendritic cells , 2016, EMBO reports.
[42] Christine E Brown,et al. Targeting Alpha-Fetoprotein (AFP)–MHC Complex with CAR T-Cell Therapy for Liver Cancer , 2016, Clinical Cancer Research.
[43] M. Shipp,et al. NLRC5/MHC class I transactivator is a target for immune evasion in cancer , 2016, Proceedings of the National Academy of Sciences.
[44] Brock F. Binkowski,et al. NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells. , 2016, ACS chemical biology.
[45] H. Einsele,et al. Karyotype complexity and prognosis in acute myeloid leukemia , 2016, Blood Cancer Journal.
[46] Meagan E. Sullender,et al. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 , 2015, Nature Biotechnology.
[47] Ole Winther,et al. BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis , 2015, Nucleic Acids Res..
[48] A. Bax,et al. A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR* , 2015, The Journal of Biological Chemistry.
[49] K. Cibulskis,et al. Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes , 2015, Nature Biotechnology.
[50] T. Rau,et al. Loss of tapasin correlates with diminished CD8+ T-cell immunity and prognosis in colorectal cancer , 2015, Journal of Translational Medicine.
[51] N. Hacohen,et al. Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity , 2015, Cell.
[52] S. Srikantan,et al. The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function. , 2014, Human molecular genetics.
[53] Christof Fellmann,et al. An optimized microRNA backbone for effective single-copy RNAi. , 2013, Cell reports.
[54] J. D. Fitzpatrick,et al. Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. , 2013, The New England journal of medicine.
[55] Hau B. Nguyen,et al. A New Protein-Protein Interaction Sensor Based on Tripartite Split-GFP Association , 2013, Scientific Reports.
[56] P. Lehner,et al. MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation , 2013, Proceedings of the National Academy of Sciences.
[57] Chunlei Wu,et al. BioGPS and MyGene.info: organizing online, gene-centric information , 2012, Nucleic Acids Res..
[58] Kevin W Eliceiri,et al. NIH Image to ImageJ: 25 years of image analysis , 2012, Nature Methods.
[59] Jing Liu,et al. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin , 2011, Proceedings of the National Academy of Sciences.
[60] Sébastien Lemieux,et al. The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation , 2011, Molecular systems biology.
[61] Chi-Jung Huang,et al. A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment , 2011, Journal of Translational Medicine.
[62] Christof Fellmann,et al. Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi , 2011, Nature Biotechnology.
[63] Patricia L. M. Dahia,et al. Germline mutations in TMEM127 confer susceptibility to pheochromocytoma , 2010, Nature Genetics.
[64] M. Ressing,et al. The Epstein-Barr Virus G-Protein-Coupled Receptor Contributes to Immune Evasion by Targeting MHC Class I Molecules for Degradation , 2009, PLoS pathogens.
[65] P. Cresswell,et al. Regulation of MHC class I assembly and peptide binding. , 2008, Annual review of cell and developmental biology.
[66] R. Weigert,et al. Rab22a regulates the recycling of membrane proteins internalized independently of clathrin. , 2004, Molecular biology of the cell.
[67] S. Batalov,et al. A gene atlas of the mouse and human protein-encoding transcriptomes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[68] K. Schroder,et al. Interferon‐γ: an overview of signals, mechanisms and functions , 2004 .
[69] P. Shannon,et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.
[70] G. Balendiran,et al. Definition and transfer of a serological epitope specific for peptide-empty forms of MHC class I. , 1999, International immunology.
[71] J. Bryant,et al. Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen. , 1996, The Journal of clinical investigation.
[72] C. Meijer,et al. Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas , 1994, The Journal of experimental medicine.
[73] N. Shastri,et al. Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[74] Hidde L. Ploegh,et al. Empty MHC class I molecules come out in the cold , 1990, Nature.
[75] A. Ribas,et al. Mechanisms of Resistance to PD-1 and PD-L1 Blockade , 2018, Cancer journal.